Publications by authors named "Yuchen Cui"

Bilirubin exists as albumin-bound complexes in the bloodstream of patients with hyperbilirubinemia. Developing adsorbents with high removal efficiency for albumin-bound bilirubin and excellent hemocompatibility is essential for effective hemoperfusion therapy. Herein, microfibrillated cellulose-reinforced polyethyleneimine cryogels (PEI/MFC) with robust mechanical properties were fabricated through cryo-induced chemical crosslinking, using bis(vinylsulphonyl)methane (BVSM) as chemical cross-linker.

View Article and Find Full Text PDF

Introduction: Temporomandibular disorders (TMD) have a high prevalence and complex etiology. The purpose of this study was to apply a machine learning (ML) approach to identify risk factors for the occurrence of TMD in adults and to develop and validate an interpretable predictive model for the risk of TMD in adults.

Methods: A total of 949 adults who underwent oral examinations were enrolled in our study.

View Article and Find Full Text PDF

In the landscape of infectious diseases, human coronaviruses such as SARS-CoV, MERS-CoV, and SARS-CoV-2 pose significant threats, characterized by severe respiratory illnesses and notable resistance to conventional treatments due to their rapid evolution and the emergence of diverse variants, particularly within SARS-CoV-2. This study investigated the development of broad-spectrum coronavirus vaccines using heterodimeric RBD-Fc proteins engineered through the "Knob-into-Hole" technique. We constructed various recombinant proteins incorporating the receptor-binding domains (RBDs) of different coronaviruses.

View Article and Find Full Text PDF

Objectives: Temporomandibular disorders (TMDs) have a relatively high prevalence among university students. This study aimed to identify independent risk factors for TMD in university students and develop an effective risk prediction model.

Methods: This study included 1,122 university students from four universities in Changchun City, Jilin Province, as subjects.

View Article and Find Full Text PDF
Article Synopsis
  • Researchers discovered new magneto-electrical quantum transitions in perovskite oxides like rare-earth nickelate (NiO), which could lead to advancements in AI and multifunctional sensors.
  • * Previous studies mainly focused on light or middle rare-earth compositions, while heavy rare-earth NiO (after Gd) faced challenges due to high-pressure synthesis requirements.
  • * This study successfully synthesized NiO using much lower pressures and temperatures, unveiling unique electrical transport properties under high pressure that highlight its potential for future applications.
View Article and Find Full Text PDF

Cholesteric liquid crystal microcapsules (CLCMs) are used to improve the stability of liquid crystals while ensuring their stimulus response performance and versatility, with representative applications such as sensing, anticounterfeiting, and smart fabrics. However, the reflectivity and angular anisotropy decrease because of the anchoring effect of the polymer shell matrix, and the influence of particle size on this has not been thoroughly studied. In this study, the effect of synthesis technology on microcapsule particle size was investigated using a complex coalescence method, and the effect of particle size on the reflectivity and angular anisotropy of CLCMs was investigated in detail.

View Article and Find Full Text PDF
Article Synopsis
  • Fr. ex Bull. is a nutritious edible mushroom noted for its medicinal benefits, primarily rich in polysaccharides, including a newly identified one called BAPN-1.
  • BAPN-1 is a glucan with a unique molecular structure and shows potent antiproliferative effects on various non-Hodgkin lymphoma (NHL) cell lines, triggering cell cycle arrest and apoptosis.
  • The study indicates that BAPN-1 works by upregulating specific proteins and inhibiting significant signaling pathways, suggesting its potential use in health products.
View Article and Find Full Text PDF

Sodium-ion batteries (SIBs), owing to their abundant resources and cost-effectiveness, have garnered considerable interest in the realm of large-scale energy storage. The properties of cathode materials profoundly affect the cycle stability and specific capacity of batteries. Herein, a series of Cu-doped spherical P2-type NaFeCuMnO ( = 0, 0.

View Article and Find Full Text PDF
Article Synopsis
  • Acmella radicans is a newly identified invasive species in Yunnan Province, China, originally from Central America, posing potential ecological risks that need assessing.
  • Using the MaxEnt model, researchers found a high probability of suitable environments for A. radicans, mainly in southern China, with significant impacts on native plant species and soil health over a five-year period.
  • The study highlights the urgent need for ongoing monitoring of A. radicans due to its predicted expansion and negative effects on local biodiversity and soil nutrients.
View Article and Find Full Text PDF

The rapid mutation of SARS-CoV-2 has led to multiple rounds of large-scale breakthrough infection and reinfection worldwide. However, the dynamic changes of humoral and cellular immunity responses to several subvariants after infection remain unclear. In our study, a 6-month longitudinal immune response evaluation was conducted on 118 sera and 50 PBMC samples from 49 healthy individuals who experienced BA.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the link between levothyroxine (LT4) treatment and adverse pregnancy outcomes in pregnant women with elevated TSH levels (2.5-10.0 mIU/L) during the first trimester, focusing on those with varying TPOAb statuses.
  • Using a retrospective cohort analysis of 4,370 pregnant women, the research employed propensity score matching to compare outcomes between those treated with LT4 and those who were not.
  • Findings revealed that LT4 treatment significantly reduced the risk of pregnancy loss but increased the likelihood of small-for-gestational-age infants and preterm birth, particularly among TPOAb-positive women with high-normal TSH levels.
View Article and Find Full Text PDF

Arthritis causes Fos-like 2 (Fosl2) inactivation, and various immune cells contribute to its pathogenesis. However, little is known about the role of Fosl2 in hematopoiesis and the possible pathological role of Fosl2 inactivation in the hematopoietic system in arthritis. In this study, we show that Fosl2 maintains hematopoietic stem cell (HSC) quiescence and differentiation while controlling the inflammatory response via macrophages.

View Article and Find Full Text PDF

The current SARS-CoV-2 variants strikingly evade all authorized monoclonal antibodies and threaten the efficacy of serum-neutralizing activity elicited by vaccination or prior infection, urging the need to develop antivirals against SARS-CoV-2 and related sarbecoviruses. Here, we identified both potent and broadly neutralizing antibodies from a five-dose vaccinated donor who exhibited cross-reactive serum-neutralizing activity against diverse coronaviruses. Through single B-cell sorting and sequencing followed by a tailor-made computational pipeline, we successfully selected 86 antibodies with potential cross-neutralizing ability from 684 antibody sequences.

View Article and Find Full Text PDF
Article Synopsis
  • Emerging SARS-CoV-2 sub-lineages, such as XBB.1.5 and BA.2.86, have raised concerns regarding the efficacy of current vaccines against them.
  • A study compared the neutralization abilities of serum from individuals vaccinated with CoronaVac and a new tetravalent vaccine, SCTV01E, as well as those who had breakthrough infections.
  • Results indicate that while some variants show increased resistance, the SCTV01E booster provides stronger protection and promotes higher levels of virus-specific memory B cells, suggesting the need for multivalent vaccines for future protection.
View Article and Find Full Text PDF

Objectives: To investigate the displacement of dentition and stress distribution on periodontal ligament (PDL) during retraction and intrusion of anterior teeth under different proclination of incisors using clear aligner (CA) in cases involving extraction of the first premolars.

Methods: Models were constructed, consisting of the maxilla, PDLs, CA and maxillary dentition without first premolars. These models were then imported to finite element analysis (FEA) software.

View Article and Find Full Text PDF

Currently, severe shuttle effects and sluggish conversion kinetics are the main obstacles to the advancement of lithium-sulfur (Li-S) batteries. Modification of the battery separator by a catalyst is a promising approach to tackle these problems, but simultaneously obtaining rich catalytic active sites, high conductivity, and remarkable stability remains a great challenge. Herein, a flower-like MXene/MoS/SnS@C heterostructure as the functional intercalation of Li-S batteries was prepared for accelerating the synergistic adsorption-electrocatalysis of sulfur conversion.

View Article and Find Full Text PDF

Evidence of antibody-dependent enhancement (ADE) of other viruses has raised concerns about the safety of SARS-CoV-2 vaccines and antibody therapeutics. In vitro studies have shown ADE of SARS-CoV-2 infection. In this study, we also found that vaccination/convalescent sera and some approved monoclonal antibodies can enhance SARS-CoV-2 infection of FcR-expressing B cells in vitro.

View Article and Find Full Text PDF

Zeolites with uniform micropores are important shape-selective catalysts. However, the external acid sites of zeolites have a negative impact on shape-selective catalysis, and the microporosity may lead to serious diffusion limitation. Herein, we report on the direct synthesis of hierarchical hollow STW-type zeolite single crystals with a siliceous exterior.

View Article and Find Full Text PDF
Article Synopsis
  • Human enterovirus A71 (EV-A71) causes hand, foot, and mouth disease (HFMD) and poses serious health risks, but there is currently no effective treatment.
  • Previous research identified ROCK1 as a crucial factor for EV-A71 replication, making it a potential drug target.
  • A study found that Dasabuvir, an HCV polymerase inhibitor, effectively suppresses EV-A71 replication and proinflammatory responses, suggesting it could be a viable candidate for treating EV-A71 and potentially other Enteroviruses A.
View Article and Find Full Text PDF

Introduction: In natural systems, diverse plant communities tend to prevent a single species from dominating. Similarly, management of invasive alien plants may be achieved through various combinations of competing species.

Methods: We used a de Wit replacement series to compare different combinations of sweet potato ( (L.

View Article and Find Full Text PDF

Practical applications of lithium-sulfur (Li-S) batteries have been hindered by sluggish reaction kinetics and severe capacity decay during charge-discharge cycling due to the notorious shuttle effect of polysulfide and the unfavored deposition and dissolution of Li S. Herein, to address these issues, a double-defect engineering strategy is developed for preparing Co-doped FeP catalyst containing P vacancies on MXene, which effectively improves the bidirectional redox of Li S. Mechanism analysis indicates that P vacancy accelerates Li S nucleation via increased unsaturated sites, and Co doping generates local electric field to reduce the reaction energy barrier and accelerate Li S dissolution.

View Article and Find Full Text PDF

This paper presents an improved empirical modal decomposition (EMD) method to eliminate the influence of the external environment, accurately compensate for the temperature drift of MEMS gyroscopes, and improve their accuracy. This new fusion algorithm combines empirical mode decomposition (EMD), a radial basis function neural network (RBF NN), a genetic algorithm (GA), and a Kalman filter (KF). First, the working principle of a newly designed four-mass vibration MEMS gyroscope (FMVMG) structure is given.

View Article and Find Full Text PDF

In order to remove noise generated during the accelerometer calibration process, an accelerometer denoising method based on empirical mode decomposition (EMD) and time-frequency peak filtering (TFPF) is proposed in this paper. Firstly, a new design of the accelerometer structure is introduced and analyzed by finite element analysis software. Then, an algorithm combining EMD and TFPF is proposed for the first time to deal with the noise of the accelerometer calibration process.

View Article and Find Full Text PDF
Article Synopsis
  • The d-band correlations in metastable rare-earth ferrites allow for unique charge ordering transitions that exceed the capabilities of conventional semiconductors, but their synthesis often requires dangerous reducing atmospheres.
  • A new method called reactive spark plasma sintering (RSPS) has been developed to synthesize these materials in a much safer coarse vacuum environment, reducing reaction time significantly.
  • This process allows for greater control over the rare-earth compositions and charge ordering transition temperatures, revealing new insights into the electronic structure and transport properties of the synthesized FeO phases.
View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_sessionfo6ncakmjf94cortcp3dbh3055r2vsln): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once