Bilayer WS shows exceptional promise for excitonic devices due to its defect tolerance, high carrier density, and angle-tunable electronic properties. However, fundamental understanding of twist angle-dependent exciton transport remains limited due to challenges in sample preparation and interplays between interlayer coupling and moiré potential. Using transient reflection microscopy (TRM), we systematically studied exciton mobility in chemical vapor deposition-grown (CVD-grown) bilayer WS with different twist angles.
View Article and Find Full Text PDFDefect detection is crucial for quality control in industrial products. The defects in industrial products are typically subtle, leading to reduced accuracy in detection. Furthermore, industrial defect detection often necessitates high efficiency in order to meet operational demands.
View Article and Find Full Text PDFImproving nanomedicine uptake by tumor cells is key to achieving intracellular drug delivery. In this study, we found that methyl-β-cyclodextrin (MβCD) can significantly promote the intracellular accumulation of nanoparticulated α-linolenic acid-paclitaxel conjugates (ALA-PTX NPs) via enhanced clathrin-mediated endocytosis and limited degradation in lysosomes. Our in vitro results indicated that MβCD not only reduced the plasma membrane cholesterol content and increased plasma membrane fluidity, leading to ALA-PTX NPs being more easily incorporated into the plasma membrane, further enhancing membrane fluidity and making the plasma membrane more susceptible to tensile deformation, forming intracellular vesicles to enhance ALA-PTX NP cellular uptake, but also destroyed lysosomes and then limited ALA-PTX NPs' degradation in lysosomes.
View Article and Find Full Text PDFTuning the oxygen activity in perovskite oxides (ABO) is promising to surmount the trade-off between activity and selectivity in redox reactions. However, this remains challenging due to the limited understanding in its activation mechanism. Herein, we propose the discovery that generating subsurface A-site cation (La) vacancy beneath surface Fe-O layer greatly improved the oxygen activity in LaFeO, rendering enhanced methane conversion that is 2.
View Article and Find Full Text PDFAmmonium dinitramide (NHN(NO), ADN) is regarded as a promising oxidizer due to its low signature and high specific impulse. Generally, ADN undergoes exothermic decomposition above 140 °C accompanied by the byproduct of ammonium nitrate (AN). The inevitable endothermic decomposition of AN decreases the overall heat release, and so there is a need to develop efficient catalysts to guide ADN decomposition along desired pathways with a lower decomposition temperature and higher heat release.
View Article and Find Full Text PDFBackground: Neonatal pneumonia is a common disease in the neonatal period with high mortality. The present work concentrated on the role and mechanism of circular RNA extra spindle pole bodies like 1, separase (circESPL1) in LPS-induced dysfunction of lung fibroblasts. Methods: Reverse transcription-quantitative polymerase chain reaction and Western blot assay were conducted to analyze RNA and protein expression, respectively.
View Article and Find Full Text PDFThe growth status of 352 malnourished and anemic children aged 0-3 years in Minhang District, Shanghai, were analyzed, and the effectiveness of health interventions was evaluated. The work focused on 352 malnourished and anemic children aged 0-3 years, summarized their health status by conducting two questionnaire surveys, and evaluated the effects of health interventions. The results revealed that the proportion of malnourished and anemic boys (57.
View Article and Find Full Text PDFAs a highly representative traditional Chinese anti-tumor medicinal material, the biomass of Mylabris is collected from the wild. However, the living environments of Mylabris is differ, so Mylabris may be contaminated by heavy metal pollution depending on the environment. These environments may also affect the amount of biosynthesis of its medicinal ingredient, cantharidin, there by affecting the quality of Mylabris.
View Article and Find Full Text PDFVarious metal oxide nanomaterials have been widely used as carriers to prepare pH-sensitive nanomedicines to respond to the acidic tumor microenvironment promoting antitumor efficiency. Herein, we used zinc oxide nanoparticles (ZnO NPs) as metal oxide nanomaterial coated with low-molecular-weight heparin (LMHP) and doxorubicin (DOX) complex (LMHP-DOX) to prepare ZnO-LD NPs for controllable pH-triggered DOX release on the targeted site. Our results indicated that the released DOX from ZnO-LD NPs was pH-sensitive.
View Article and Find Full Text PDFThe biofilms produced by the aggregation of bacterial colonies are among the major obstacles of host immune system monitoring and antimicrobial treatment. Herein, we report PEGylated dihydromyricetin-loaded liposomes coated with tea saponin grafted on chitosan (TS/CTS@DMY-lips) as an efficient cationic antibacterial agent against () and (), which is supported by their deep penetration into bacterial biofilms and broad pH-stable release performance of dihydromyricetin (DMY). The successful construction of the drug delivery system relied on tea saponin grafted on chitosan (TS/CTS) formatted ester bonds or amido bonds as a polyelectrolyte layer of PEGylated dihydromyricetin-loaded liposomes (DMY lips), which achieved controlled release of DMY in weak acidic and neutral physiological environments.
View Article and Find Full Text PDFMylabris is the dried body of the Chinese blister beetle (Mylabris sp.), which has been used in traditional Chinese medicine and achieved significant positive effects in the treatment of cancer including liver cancer, lung cancer, and rectal cancer. However, heavy metal pollution and accumulation of Mylabris insects could pose threat to human health.
View Article and Find Full Text PDFThe results of this reported work indicated that gold nanoparticle arrays self-assembled on indium tin oxide (ITO) glasses can obtain broader localized surface plasmon resonance (LSPR) wavelength range and higher sensitivity than the bare quartz. The results of surface electric field calculated using finite difference time domain showed that the electric field of nanoparticles on ITO glasses is enhanced and the repulsive forces within each particle is weakened. According to the dipolar interaction mechanism, a weakened repulsive forces within each particle lead to a lower resonance frequency and a strong redshift of the LSPR spectra.
View Article and Find Full Text PDFInjectable neurostimulators are currently applied in clinical trials to minimize the side effects such as discomfort, risk of infection, and post-surgery trauma, which can be pronounced with conventional, bulky implantable neurostimulators. Owing to its smaller size, wireless-updatable software, and wireless power supply, the injectable neurostimulator is presumably less invasive, 'smarter', and has a longer lifetime. We discuss the concept and development of the injectable neurostimulator, persistent implementation challenges, and obstacles to be overcome in its evolution.
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