A photo-responsive self-healing hydrogel loaded with immunoadjuvants and MoS nanosheets for combating post-resection breast cancer recurrence.

Tumor recurrence after surgical resection remains a significant challenge in breast cancer treatment. Immune checkpoint blockade therapy, as a promising alternative therapy, faces limitations in combating tumor recurrence due to the low immune response rate. In this study, we developed an implantable photo-responsive self-healing hydrogel loaded with MoS nanosheets and the immunoadjuvant R837 (PVA-MoS-R837, PMR hydrogel) for generation of tumor-associated antigens at the post-surgical site of the primary tumor, enabling sustained and effective activation of the immune response.

Comparison of microbial communities from different Jinhua ham factories.

Microbes in different aged workshops play important roles in the flavor formation of Jinhua ham. However, microbial diversity, community structure and age related changes in workshops are poorly understood. The microbial community structure and diversity in Jinhua ham produced in factories that have 5, 15, and 30 years of history in processing hams were compared using the pyrosequencing technique.