Publications by authors named "Yubao Zhang"

Postoperative corneal biomechanical evaluation is of great significance in clinical monitoring and management since corneal transplantation is one of the main methods to improve visual function. In this paper, we propose an OCE system based on a small ultrasound transducer to realize the in vivo detection of postoperative corneal elasticity in different directions. It was first validated and analyzed by different agar, and then the elasticity changes in normal cornea and post-transplant corneal implants and implant beds were further investigated.

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Evaluating the biomechanical properties of the lens and lens capsule is important for the clinical diagnosis and treatment of age-related cataracts and presbyopia. In this study, we developed an optical coherent elastography technique to assess the elasticity of the lens and lens capsule in the human eye. With age, the mean Young's modulus of the lens increased from 12.

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The rhizosphere, where plant roots interact intensely with the soil, is a crucial but understudied area in terms of the impact of virus infection. In this study, we investigated the effects of lily symptomless virus (LSV) and cucumber mosaic virus (CMV) on the Lanzhou lily (Lilium davidii var. unicolor) rhizosphere using metagenomics and bioinformatics analysis.

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Article Synopsis
  • - The study focuses on the limbus's elasticity, which is important for eye health, but has not been thoroughly researched.
  • - Researchers used a technique called acoustic radiation force optical coherence elastography (ARF-OCE) to measure the limbus's biomechanical properties at different eye pressures and validated it with models.
  • - Findings revealed that ARF-OCE helps visualize the limbus's elasticity, which could improve the diagnosis of eye conditions by identifying variations in elasticity related to ocular diseases.
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Background: Pancreatic cancer is one of the deadliest cancers in the world. In recent years, the incidence and mortality rates of pancreatic cancer have shown an increasing trend year by year. This study investigates the independent effects of age, period, and cohort on the global incidence, mortality, and disability-adjusted life years (DALYs) of pancreatic cancer from 1990 to 2019, and evaluates the differences in the burden of pancreatic cancer across regions with different Sociodemographic Index (SDI) levels.

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  • Raspberry plants (Rubus corchorifolius) are economically and medicinally significant in China, but farmers in Gansu Province face issues with root rot disease affecting about 30% of crops.
  • A thorough field survey conducted in June 2022 led to the collection of both diseased and healthy plants for pathogen identification, resulting in the isolation of 22 distinct Fusarium strains.
  • One specific strain, RB10, was linked to observed symptoms and showed distinct morphological traits of Fusarium avenaceum, confirmed through genetic sequencing techniques.
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  • * A novel positron annihilation lifetime spectrometer is used to analyze liquid scintillator samples without touching the positron source, providing accurate measurements and low background interference.
  • * Results include a measured ortho-positronium lifetime of 3.02 ns, insights on oxygen's interaction with positronium, and calculations related to annihilation rate and free volume, which may improve understanding of gas solubility in liquids.
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Potato is an important crop due to its high contents of starch, protein, and various vitamins and minerals. Biofertilizers are composed of plant growth promoting microbes (PGPMs) which are essential for improving the growth and resistance of potato. However, little information has focused on the modes of inoculation of biofertilizers on plant growth and microecology.

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Quantifying the biomechanical properties of the tongue is significant for early diagnosis of tongue carcinoma. Therefore, an intraoral optical coherence elastography system based on a miniature probe was proposed here to evaluate the viscoelasticity of tongue for the first time. Results of experiments with Sprague-Dawley rats indicate that considerable elasticity diversity occurred between cancerous and normal tongues, and the corresponding ratio of their Young's modulus was evaluated to be 3.

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  • Triple-negative breast cancer (TNBC) is marked by high variability and currently has limited treatment options, leading to poor patient outcomes; Paris saponin VII (PSⅦ) shows promise for its anti-cancer effects but its role against TNBC is still not well understood.
  • This study utilized single-cell sequencing and gene analysis to identify STMN1 as a crucial biomarker linked to patient prognosis in TNBC and revealed its involvement in the MAPK signaling pathway.
  • Experimental results demonstrated that PSⅦ effectively inhibits TNBC cell proliferation, migration, and invasion while promoting cell death, suggesting it works by interacting with MEK protein and disrupting related signaling pathways.
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Background: This study used optical coherence tomography (OCT) to observe real-time internal gap formation in both bulk-fill and conventional resin composites. It aimed to provide a quantitative analysis of variations, addressing the inconclusive nature of microleakage assessment caused by differences in testing methods.

Methods: Fifty extracted third molars prepared with Class I cavities, were divided into five groups (n = 10).

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Astragalus mongholicus is a medicinal plant that is known to decrease in quality in response to continuous cropping. However, the differences in the root-associated microbiome and root exudates in the rhizosphere soil that may lead to these decreases are barely under studies. We investigated the plant biomass production, root-associated microbiota, and root exudates of A.

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The damage behavior and defect evolution in Si-doped and Fe-doped β-GaO crystals were investigated using an electron irradiation of 1 MeV at a dose of 1 × 10 cm in conjunction with structural and optoelectronic characterizations. Distinct decline in electron spin resonance (ESR) signal with = 1.96 and a UV luminesce of 375 nm were observed in Si-doped β-GaO due to the capture of free carriers by irradiation defects.

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Quantifying corneal elasticity after femtosecond laser-assisted in situ keratomileusis (FS-LASIK) procedure plays an important role in improving surgical safety and quality, since some latent complications may occur ascribing to changes in postoperative corneal biomechanics. Nevertheless, it is suggested that current research has been severely constrained due to the lack of an accurate quantification method to obtain postoperative corneal elasticity distribution. In this paper, an acoustic radiation force optical coherence elastography system combined with the improved phase velocity algorithm was utilized to realize elasticity distribution images of the in vivo rabbit cornea after FS-LASIK under various intraocular pressure levels.

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The constraint of phosphorus (P) fixation on crop production in alkaline calcareous soils can be alleviated by applying bioinoculants. However, the impact of bacterial inoculants on this process remains inadequately understood. Here, a field study was conducted to investigate the effect of a high-concentration, cost-effective, and slow-release granular bacterial inoculant (GBI) on maize (Zea mays L.

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Significance: Previous studies have demonstrated that the biomechanical properties of the optic nerve head (ONH) are associated with a variety of ophthalmic diseases; however, they have not been adequately studied.

Aim: We aimed to obtain a two-dimensional (2D) velocity distribution image based on the one-to-one correspondence between velocity values and position using the acoustic radiation force optical coherence elastography (ARF-OCE) technique combined with a 2D phase velocity algorithm.

Approach: An ARF-OCE system has the advantages of non-invasive detection, high resolution, high sensitivity, and high-speed imaging for quantifying the biomechanical properties of the ONH at different intraocular pressures (IOPs) and detection directions.

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The scleral elasticity is closely related with many ocular diseases, but the relevant research is still insufficient. Here, we utilized optical coherence elastography to carefully study biomechanical properties of the sclera at different positions and under different intraocular pressures. Meanwhile, elastic wave velocity and Young's modulus of each position were obtained using a phase velocity algorithm.

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  • Gravel mulch, commonly used in semi-arid regions of northwest China for water conservation, is showing reduced effectiveness due to soil degradation from prolonged use.
  • A 6-year study on the Loess Plateau revealed that gravel mulching increased total carbon and organic carbon levels but altered microbial diversity and abundance, with different gravel sizes affecting microbial communities differently.
  • The findings suggest that changes in soil composition due to gravel mulching contribute to land degradation, highlighting the need for more long-term studies to understand the underlying mechanisms.
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  • Triple-negative breast cancer (TNBC) is a challenging subtype of breast cancer with limited treatment options, prompting research into alternative therapies such as Matrine (MAT) from the plant Sophora flavescens.
  • Bioinformatics and network pharmacology analyses highlighted MAT's potential to inhibit TNBC cell proliferation and invasion, with experimental results showing MAT induced apoptosis, arrested the cell cycle, and triggered autophagy in TNBC cells.
  • MAT was found to inhibit the PI3K/AKT signaling pathway, which may serve as a key target for developing new treatments against TNBC.
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It is well established that forest type can have a profound impact on soil physicochemical properties but the associated changes in soil microbial communities and the mechanisms by which soil quality is improved by various plantations are not fully understood. In this study, soil physicochemical properties and microbial and enzyme activities were investigated in four forest types- pure forests (CHPF), - mixed forests (CHPEF), - mixed forests (CHMMF), and - mixed forests (CHMLF) in the subtropical region of China. The purpose of this study was to assess the effects of afforestation types on characteristics of soil-its physical, chemical, and biological properties.

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Background: Tooth bleaching imparts whitening effects along with adverse effects such as increased tooth sensitivity and enamel surface changes. Herein, we employed optical coherence tomography (OCT), a nondestructive optical detection technique, for evaluation of tooth enamel after treatment with peroxide-based bleaching agents.

Methods: Fifteen enamel samples were bleached using 38% acidic hydrogen peroxide-based bleach, subjected to OCT scanning, and then cross-sectioned and imaged under polarized light microscopy (PLM) and transverse microradiography (TMR).

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Celery (Apium graveolens L.) is an economically important vegetable crop in China. In recent years, celery has been widely planted in Yuzhong county, Gansu province.

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Hepatocellular carcinoma (HCC) is a grievous tumor with an increasing incidence worldwide. Basic transcription factor 3 (BTF3) is discovered to regulate the expression of glucose transporter 1 (GLUT1), which benefits glycolysis, a momentous signature of tumors, through transactivation of the forkhead box M1 (FOXM1) expression. BTF3 is highly expressed in HCC.

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Gansu Province is a district renowned for the cultivation of (Oliv.) Diels, accounting for greater than 90% of China's total annual production. However, virus infection has caused a reduction in yield.

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