Analysis of foodborne outbreaks in Wenzhou City, China, 2012-2022.

Foodborne diseases are ongoing and significant public health concerns. This study analysed data obtained from the Foodborne Outbreaks Surveillance System of Wenzhou to comprehensively summarise the characteristics of foodborne outbreaks from 2012 to 2022. A total of 198 outbreaks were reported, resulting in 2,216 cases, 208 hospitalisations, and eight deaths over 11 years.

[Relationship between macrophage pyroptosis and atherosclerosis based on theory of "spleen in correlation with endoplasmic reticulum"].

The key pathogenesis of atherosclerosis(AS) in traditional Chinese medicine(TCM) lies in the combination of phlegm and stasis due to spleen deficiency. In Western medicine, it is believed that pyroptosis can lead to atherosclerosis, and endoplasmic reticulum stress has been shown to promote pyroptosis. According to the theories of " spleen in correlation with endoplasmic reticulum",guided by spleen governing transportation and transformation, and endoplasmic reticulum processing proteins, it is believed that the syndrome of phlegm combined with stasis due to spleen deficiency has similarities with the mechanism of macrophage pyroptosis induced by endoplasmic reticulum stress in accelerating the progression of AS.

Construction and Biological Evaluation of Different Nanoshell Thickness Ni@SiO2 Nanotubes as Good Protein Separation Carriers for Bovine Hemoglobin.

Background: Nickel nanomaterials play an important role in biological applications, but they have high toxicity and poor biocompatibility. To overcome these defects, we coated the surface of Ni nanotubes with different thicknesses of SiO2 to reduce cytotoxicity, improve biocompatibility, and broaden their biological application value.

Objective: This study aimed to construct Ni nanotubes with different thicknesses of SiO2 nanoshells; investigate the effects of silicon layer thickness, incubation time, and cell line category on the cytotoxicity of the as-synthesized materials, and evaluate the biocompatibility of the materials by biological enzymes.

Conditional convolutional GAN-based adaptive demodulator for OAM-SK-FSO communication.

The perturbation of atmosphere turbulence is a significant challenge in orbital angular momentum shift keying-based free space optical communication (OAM-SK-FSO). In this study, we propose an adaptive optical demodulation system based on deep learning techniques. A conditional convolutional GAN (ccGAN) network is applied to recover the distorted intensity pattern and assign it to its specified class.

Association of interleukin-6, ferritin, and lactate dehydrogenase with venous thromboembolism in COVID-19: a systematic review and meta-analysis.

Background: Coronavirus disease 2019 (COVID-19) is frequntly accompanied by venous thromboembolism (VTE), and its mechanism may be related to the abnormal inflammation and immune status of COVID-19 patients. It has been proved that interleukin-6 (IL-6), ferritin and lactate dehydrogenase (LDH) may play an important role in the occurrence of VTE in COVID-19 infection. But whether they can server as predictors for VTE in COVID-19 is still unclear.

Radiomics-clinical nomogram for preoperative lymph node metastasis prediction in esophageal carcinoma.

Objectives: This research aimed to develop a radiomics-clinical nomogram based on enhanced thin-section CT radiomics and clinical features for the purpose of predicting the presence or absence of metastasis in lymph nodes among patients with resectable esophageal squamous cell carcinoma (ESCC).

Methods: This study examined the data of 256 patients with ESCC, including 140 cases with lymph node metastasis. Clinical information was gathered for each case, and radiomics features were derived from thin-section contrast-enhanced CT with the help of a 3D slicer.

Electron transfer coupled spin transition in cyano-bridged mixed-valence {FeIII2FeII2} molecular squares.

The research on electron transfer coupled spin transition regulating the valence state and spin state transition of metal ions is promising and challenging. Herein, we report a cyano-bridged {FeIII2FeII2} molecular square complex, {[Fe(Tp)(CN)] [Fe(bnbpen)]}(ClO)·8CHOH (1·8CHOH, bnbpen = ,'-bis-(2-naphthylmethyl)-,'-bis(2-picolayl)-ethylenediamine), and its free of solvents form (1). Combined single-crystal X-ray diffraction, temperature-dependent infrared (IR) spectra, magnetic measurements, and Mössbauer spectra reveal that 1·8CHOH and 1 exhibit reversible one-step and two-step electron transfer coupled spin transition (ETCST) with temperature change, between the low-temperature state {Fe(μ-CN)Fe} (LS = low spin, HS = high spin) and the high-temperature state {Fe(μ-CN)Fe}, respectively.

Closed-loop recovery of molybdenum and value-added reuse of tungsten from alloy waste in additive manufacturing.

As metal additive manufacturing (MAM) technology is booming in the aerospace sector, alternatives to the traditional production methods of metals such as mining, processing, and refining with severe emissions are urgently needed. This study proposed a closed-loop route for efficient recovery of molybdenum (Mo) and value-added reuse of tungsten (W) from Cr-Co-Ni-Mo-W alloy waste in MAM. The results showed that the leaching efficiency of Mo and W reached 99.

Molecular typing and characterization of isolates from burn wound infections in Fujian, China.

Background: () is the most common causative agent of burn wound infection, that often leads to high morbidity and mortality. However, there is not enough knowledge about the molecular epidemiology and antimicrobial susceptibility of isolates from burn wound infections in Fujian, China.

Methods: Between 2016 and 2021, 90 isolates were collected from burn wound infections in Fujian, China, including 59 methicillin-resistant (MRSA) strains and 31 methicillin-susceptible (MSSA) strains.

Comprehensive evaluation of time-varied outcomes for invasive and conservative strategies in patients with NSTE-ACS: a meta-analysis of randomized controlled trials.

Background: Results from randomized controlled trials (RCTs) and meta-analyses comparing invasive and conservative strategies in patients with non-ST-elevation acute coronary syndrome (NSTE-ACS) are highly debatable. We systematically evaluate the efficacy of invasive and conservative strategies in NSTE-ACS based on time-varied outcomes.

Methods: The RCTs for the invasive versus conservative strategies were identified by searching PubMed, Cochrane Central Register of Controlled Trials, Embase, and ClinicalTrials.

Comparative genomics of the medicinal plants Lonicera macranthoides and L. japonica provides insight into genus genome evolution and hederagenin-based saponin biosynthesis.

Lonicera macranthoides (LM) and L. japonica (LJ) are medicinal plants widely used in treating viral diseases, such as COVID-19. Although the two species are morphologically similar, their secondary metabolite profiles are significantly different.

Food safety in health: a model of extraction for food contaminants.

Contaminants are the critical targets of food safety supervision and risk assessment. In existing research, food safety knowledge graphs are used to improve the efficiency of supervision since they supply the relationship between contaminants and foods. Entity relationship extraction is one of the crucial technologies of knowledge graph construction.

A Kaposi's sarcoma-associated herpes virus-encoded microRNA contributes to dilated cardiomyopathy.

Dilated cardiomyopathy (DCM) is the leading cause of heart transplantation. By microRNA (miRNA) array, a Kaposi's sarcoma-associated herpes virus (KSHV)-encoded miRNA, kshv-miR-K12-1-5p, was detected in patients with DCM. The KSHV DNA load and kshv-miR-K12-1-5p level in plasma from 696 patients with DCM were measured and these patients were followed-up.

A novel conditional survival nomogram for monitoring real-time prognosis of non-metastatic triple-negative breast cancer.

Background: Conditional survival (CS) is defined as the possibility of further survival after patients have survived for several years since diagnosis. This may be highly valuable for real-time prognostic monitoring, especially when considering individualized factors. Such prediction tools were lacking for non-metastatic triple-negative breast cancer (TNBC).

Class-dependent and cross-modal memory network considering sentimental features for video-based captioning.

The video-based commonsense captioning task aims to add multiple commonsense descriptions to video captions to understand video content better. This paper aims to consider the importance of cross-modal mapping. We propose a combined framework called Class-dependent and Cross-modal Memory Network considering SENtimental features (CCMN-SEN) for Video-based Captioning to enhance commonsense caption generation.

Exercise effect on the gut microbiota in young adolescents with subthreshold depression: A randomized psychoeducation-controlled Trial.

This 3-month randomized psychoeducation-controlled trial (RCT) of exercise was undertaken in young adolescents with subthreshold depression to examine the impact on gut microbiota. Participants (aged 12-14 years) were randomly assigned to an exercise or a psychoeducation-controlled group. The exercise intervention arm took moderate-intensity exercise, comprised of 30 min of running per day, 4 days a week for 3 months.

Morphology and Enzyme-Mimicking Activity of Copper Nanoassemblies Regulated by Peptide: Mechanism, Ultrasensitive Assaying of Trypsin, and Screening of Trypsin Inhibitors.

To regulate nanostructure synthesis is of crucial importance for developing various applications, including catalysis, bioanalysis, and optical devices. Herein, the morphology and peroxidase (POD)-mimicking activity of peptide-templated copper nanoassemblies (Cu NAs) are regulable with peptide types. The Cu NAs templated with peptide containing single cysteine are uniform nanoclusters with strong POD-like activity.

Evidence Summary for Nonpharmacological Management of Chemotherapy-Induced Nausea and Vomiting.

Objective: To evaluate and summarize the best evidence for nonpharmacological management of chemotherapy induced nausea and vomiting (CINV). This article aims at serving as a reference for nursing staff to prevent and manage CINV.

Methods: We systematically searched for evidence on CINV in databases such as Cnki and Wanfang, guide websites such as GIN and NZGG, and professional websites such as UICC and ACS.

BMS-202, a PD-1/PD-L1 inhibitor, decelerates the pro-fibrotic effects of fibroblasts derived from scar tissues via ERK and TGFβ1/Smad signaling pathways.

Introduction: Hypertrophic scar (HS), a fibroproliferative disorder of the skin with some tumor-like properties, is closely related to dysregulated inflammation. PD-1/PD-L1 inhibitor is a promising medication for cancer therapy as its potent functions on adaptive immune response; whether it could be a candidate for HS therapy has aroused our interest. This study aimed to explore the effect and the mechanism of BMS-202, a PD-1/PD-L1 inhibitor, in HS.

Intervention effect of encouraging mental and programmed nursing of patients in interventional operating room on their compliance and bad moods.

Background: Patients' lack of correct understanding of cardiovascular disease and interventional therapy is often accompanied by varying degrees of fear, depression and anxiety. Negative emotion will affect the hemodynamic fluctuation of patients undergoing interventional surgery, which is not conducive to the smooth and safe operation of interventional surgery. Therefore, it is very important to implement effective nursing intervention in the operating room.

Compact Slot Microring Resonator for Sensitive and Label-Free Optical Sensing.

A novel all-pass slot microring resonator (SMRR), intended for label-free optical biosensing based on silicon-on-insulator platforms, is proposed. The sensor consists of a bent asymmetric directional coupler and an asymmetric-slot microring waveguide. The appropriate slot width of 140 nm is identified by the three-dimensional finite-difference time-domain (3D-FDTD) method for better light-matter interaction in applications.

Energy consumption in China: Spatial effects of industrial concentration, localization, and diversity.

This paper discusses the effects of industrial agglomeration on electrical energy consumption from a spatial perspective by highlighting multiple agglomeration types. It is argued that different types of industry agglomeration may exert differentiated effects on energy consumption and their possible spatial interactions. With city sector panel data of China's 285 prefecture-level cities for the period 2003-2013, we adopted the Spatial Durbin Model (SDM) with fixed effects to examine the spatial effects of industrial agglomeration types on energy consumption.