Publications by authors named "Yuanyu Liu"
Article Synopsis
- The study investigates the best ways to use polymyxins for treating multidrug-resistant gram-negative bacterial pneumonia, focusing on their effectiveness and safety through a network meta-analysis of various treatment regimens.
- It analyzed data from 22 studies, finding that combining intravenous and inhaled polymyxins (IV+IH) significantly reduced overall mortality and improved clinical outcomes compared to just intravenous or inhaled options alone.
- The results indicate that the IV+IH regimen is the most effective, showing higher rates of microbial eradication and clinical success compared to IV and inhaled-only treatments.
ε-poly-L-lysine (ε-PL) is the main secondary metabolite of Streptomyces albulus, and it is widely used in the food industry. Polylysine synthetase (Pls) is the last enzyme in the ε-PL biosynthetic pathway. Our previous study revealed that Pls overexpressed in S.
View Article and Find Full Text PDFEnterovirus (EV) 71 caused episodes of outbreaks in China and Southeast Asia during the last few decades. We have previously reported that EV71 induces reactive oxygen species (ROS). However, the underlying mechanism remains elusive.
View Article and Find Full Text PDF