Publications by authors named "Yuanying Qian"
Article Synopsis
- DEC205 (CD205) is a key endocytic receptor on dendritic cells used in immune therapies, and it has a specific ability to recognize dead cells via keratins in a pH-dependent way.
- The crystal structure analysis shows that DEC205 is similar to other mannose receptor family members, but has unique features in its individual domains that affect ligand binding.
- Research revealed an XGGGX motif in keratins that DEC205 recognizes, enhancing our understanding of its interactions and the broader ligand specificities within the mannose receptor family.
