Childhood and adult socioeconomic status influence on late-life healthy longevity: evidence from the Chinese longitudinal healthy longevity survey.

Background: Older people in low- and middle-income countries are more susceptible to the impact of childhood experiences. This study comprehensively examines how childhood socioeconomic status (SES) and adult SES collectively influence late-life healthy longevity from a life course perspective, providing insights for shaping health-related policies.

Methods: This study analyzed data from the Chinese Longitudinal Healthy Longevity Survey (1998-2018) with 37,264 individuals aged 65 and above.

Analysis of Cross-Regional Transfer of Food Safety Risks and Its Influencing Factors-An Empirical Study of Five Provinces in East China.

The cross-regional transfer of food safety risks has become more prominent, bringing new challenges to food safety regulation. This study used a social network analysis to delve into the nuanced features and determinants of the cross-regional transfer of food safety risks based on the food safety inspection data of five provinces in East China from 2016 to 2020, thus contributing to the establishment of effective cross-regional cooperation in food safety regulation. The main findings are as follows: First, the cross-regional transfer of unqualified products accounts for 36.

microRNA signature and expression of Dicer and Drosha can predict prognosis and delineate risk groups in neuroblastoma.

Neuroblastoma is a common childhood tumor and accounts for 15% of pediatric cancer deaths. To investigate the microRNA (miRNA) profile and role of Dicer and Drosha in neuroblastoma, we assessed the expression of 162 human miRNAs, Dicer and Drosha in 66 neuroblastoma tumors by using real-time PCR methods. We found global downregulation of miRNA expression in advanced neuroblastoma and identified 27 miRNAs that can clearly distinguish low- from high-risk patients.

Observation of peptide differences between cancer and control in gastric juice.

Biomarkers for various diseases have been extensively searched for the past 5 years. Nevertheless, most efforts were focused on the search for protein biomarkers from serum samples. In this work, we tried to look for peptide biomarkers from gastric juice samples with MALDI-TOF-MS.