Epidemiological characteristics of eleven common respiratory viral infections in children.

Background: Lower respiratory tract infections (LRTIs) are one of the leading causes of hospital admissions among children. In this study, we aimed to describe the epidemiological characteristics of viral pathogens associated with LRTIs in hospitalized children in Yan'an; this has yet to be reported in the literature and may guide public health interventions and resource allocation in this region.

Methods: Between June 2021 and May 2023, we conducted a retrospective analysis of the results of viral detection using oral pharyngeal swabs from 4565 children with LRTIs in the Inpatient Department of Yan'an University Affiliated Hospital.

Effect of PFDTS/TiO Coating on Microstructure and Wetting Behavior of Phosphogypsum.

Phosphogypsum (PG) constitutes a form of solid byproduct emanating from the manufacturing process of wet-process phosphoric acid. The fabrication of one metric ton of wet-process phosphoric acid entails the generation of approximately five tons of phosphogypsum, a highly prolific and economically viable waste stream. If we can effectively solve the problem of poor hydrophobicity of phosphogypsum, it is possible to replace cement and other traditional cementitious materials.

Hollow VO microspheres anchored on graphene as advanced cathodes for aqueous zinc-ion batteries.

Vanadium dioxide-based materials have been proved to be promising cathodes for aqueous zinc ion batteries (AZIBs) due to their cost-effectiveness and high theoretical specific capacity; nevertheless, the low electronic conductivity and poor cycle stability restrict their application. Herein, hollow VO microspheres anchored on graphene oxide (H-VO@GO) are synthesized via a facile simple hydrothermal reaction as high-performance cathodes for AZIBs. The hollow micromorphology of the material provides a large specific surface area and effectively alleviates the volume changes during cycling, while the anchoring of VO on graphene oxide greatly improves the electronic conductivity and inhibits the agglomeration and pulverization of the material.

Utilizing symmetrical tetramethyl cucurbit[6]uril-based supramolecular fluorescence probe for detection of paraquat in water.

A supramolecular fluorescence probe has been developed using a symmetrical tetramethyl cucurbit[6]uril (TMeQ[6]) and a styryl derivative (SPy) with a host-guest ratio of 2:1. The introduction of paraquat (PQ) competes with SPy for the TMeQ[6] cavity, resulting in fluorescent quenching. The addition of 17 common herbicides and ions had negligible effects on the fluorescence quenching, indicating that the 2TMeQ[6]/SPy complex exhibits excellent selectivity in detecting PQ.

Molybdenum-optimized electronic structure and micromorphology to boost zinc ions storage properties of vanadium dioxide nanoflowers as an advanced cathode for aqueous zinc-ion batteries.

Recently, vanadium dioxide (VO) has been recognized as one of the most prospective cathodes for aqueous zinc ion batteries (AZIBs) for its high reversible specific capacity; nevertheless, its Zn diffusion kinetics and cycling stability have not yet met expectations. Herein, Mo ions are introduced into VO to optimize the intrinsic electronic structure and micromorphology of VO, achieving significantly enhanced zinc-ion storage. It is found that the substitution of Mo for V narrows the band gap of VO and thus enhances the conductivity of the material, while VO nanorods are transformed into VO nanoflowers which are self-assembled from ultra-thin nanosheets after the introduction of Mo, exposing much more active sites to enhance the migration kinetics of Zn.

Copper Hexacyanoferrate Solid-State Electrolyte Protection Layer on Zn Metal Anode for High-Performance Aqueous Zinc-Ion Batteries.

Zinc (Zn) metal possesses broad prospects as an anode for aqueous zinc-ion batteries (AZIBs) due to its considerable theoretical capacity of 820 mAh g . However, the Zn anode suffers from dendrite growth and side reactions during Zn stripping/plating. Herein, a Prussian blue analog of copper hexacyanoferrate (CuHCF) with a 3D open structure and rich polar groups (CN) is coated on Zn foil as a solid-state electrolyte (SSE) protection layer to protect the Zn anode.

The perspectives of family caregivers of people with Alzheimer´s disease regarding advance care planning in China: a qualitative research.

Objectives: Advance care planning (ACP) enables people to define goals and preferences for future medical treatment and care. Despite universal recognition of the importance of ACP for people with Alzheimer´s disease (AD) internationally, there is little support for its implementation in China. The viewpoint of family caregivers is crucial in making clinical decisions about AD.

In-situ regulation of zinc metal surface for Dendrite-Free Zinc-ion hybrid supercapacitors.

Aqueous Zn-ion hybrid supercapacitors (ZHSCs) combine the high power density of supercapacitors with the high energy density of batteries. However, the growth of dendrite and spontaneous Zn corrosion damage the service life of ZHSCs and further seriously restrict their large-scale application in energy storage fields. Herein, we study the corrosion mechanism of Zn metal in ZnSO solution and report a method for the modification of Zn anode with zeolitic imidazolate framework-8 (ZIF-8) layer grown in-situ.

Molecular epidemiologic study of citrin deficiency by screening for four reported pathogenic SLC25A13 variants in the Shaanxi and Guangdong provinces, China.

Background: Citrin deficiency (CD) is an autosomal recessive disease resulting from biallelic mutations of the gene. This study aimed to investigate the molecular epidemiological features of CD in the Guangdong and Shaanxi provinces of China.

Methods: A total of 3,409 peripheral blood samples from Guangdong and 2,746 such samples from Shaanxi province were collected.

Asthma does not influence the severity of COVID-19: a meta-analysis.

Objective: Previous studies have reported a correlation between coronavirus disease-2019 (COVID-19) and asthma. However, data on whether asthma constitutes a risk factor for COVID-19 and the prevalence of asthma in COVID-19 cases still remain scant. Here, we interrogated and analyzed the association between COVID-19 and asthma.

A comparative study on the accumulation, translocation and transformation of selenite, selenate, and SeNPs in a hydroponic-plant system.

Plants can play important roles in overcoming selenium (Se) deficiency and Se toxicity in various regions of the world. Selenite (SeIV), selenate (SeVI), as well as Se nanoparticles (SeNPs) naturally formed through reduction of SeIV, are the three main Se species in the environment. The bioaccumulation and transformation of these Se species in plants still need more understanding.

Enterovirus 71-induced has-miR-21 contributes to evasion of host immune system by targeting MyD88 and IRAK1.

Enterovirus71(EV71), the etiological agent of hand-foot-and-mouth disease, has increasingly become a public health challenge around the world. Type I interferons (IFNs) are an important family of cytokines that regulate innate and adaptive immune responses to pathogens.These pathways are tightly regulated by the host to prevent an inappropriate cellular response, but viruses can modulate these pathways to proliferate and spread.

LSD1-mediated epigenetic modification contributes to ovarian cancer cell migration and invasion.

Lysine-specific demethylase 1 (LSD1) has been implicated in the process of tumor progression at various steps, but its role in epithelial-messenchymal transition (EMT) and the migration of ovarian cancer cells remains obscure. In this study, we demonstrated the effect of LSD1 on ovarian cancer cell migration and the regulatory role of LSD1 in the expression of EMT markers. Inhibition of LSD1 expression impaired the migration and invasion of HO8910 ovarian cancer cells.

Lysine-specific demethylase 1 mediates epidermal growth factor signaling to promote cell migration in ovarian cancer cells.

Epigenetic abnormalities play a vital role in the progression of ovarian cancer. Lysine-specific demethylase 1 (LSD1/KDM1A) acts as an epigenetic regulator and is overexpressed in ovarian tumors. However, the upstream regulator of LSD1 expression in this cancer remains elusive.