A multichannel electromyography dataset for continuous intraoperative neurophysiological monitoring of cranial nerve.

Continuous Intraoperative Neurophysiologic Monitoring (cIONM) is a widely used technology to improve surgical outcomes and prevent cranial nerve injury during skull base surgery. Monitoring of free-running electromyogram (EMG) plays an important role in cIONM, which can be used to identify different discharge patterns, alert the surgeon to potential nerve damage promptly, etc. In this dataset, we collected clinical multichannel EMG signals from 11 independent patients' data using a Neuromaster G1 MEE-2000 system (Nihon Kohden, Inc.

Superpixel-Oriented Label Distribution Learning for Skin Lesion Segmentation.

Lesion segmentation is a critical task in skin cancer analysis and detection. When developing deep learning-based segmentation methods, we need a large number of human-annotated labels to serve as ground truth for model-supervised learning. Due to the complexity of dermatological images and the subjective differences of different dermatologists in decision-making, the labels in the segmentation target boundary region are prone to produce uncertain labels or error labels.

Automatic Detection of Age-Related Macular Degeneration Based on Deep Learning and Local Outlier Factor Algorithm.

Age-related macular degeneration (AMD) is a retinal disorder affecting the elderly, and society's aging population means that the disease is becoming increasingly prevalent. The vision in patients with early AMD is usually unaffected or nearly normal but central vision may be weakened or even lost if timely treatment is not performed. Therefore, early diagnosis is particularly important to prevent the further exacerbation of AMD.

A Novel Wearable Flexible Dry Electrode Based on Cowhide for ECG Measurement.

The electrocardiogram (ECG) electrode, as a sensor, is an important part of the wearable ECG monitoring device. Natural leather is rarely used as the electrode substrate. In this paper, wearable flexible silver electrodes based on cowhide were prepared by sputtering and brush-painting.

[Experimental studies for noninvasive assessment of portal vein pressure based on contrast enhanced subharmonic sonographic imaging].

Portal hypertension (PHT) is a common complication of liver cirrhosis, which could be measured by the means of portal vein pressure (PVP). However, there is no report about an effective and reliable way to achieve noninvasive assessment of PVP so far. In this study, firstly, we collected ultrasound images and echo signals of different ultrasound contrast agent (UCA) concentrations and different pressure ranges in a low-pressure environment based on an simulation device.

Method of calculating porosity based on M44 element images of the Mueller matrix.

As a drug carrier, the porosity of porous electrospun fiber can greatly affect its drug loading ability and stability. In this work, a method to calculate the porosity of porous electrospun fiber with a polarization micrograph is described. Different porosities of porous electrospun fibers were measured by scanning electron microscope images and transmission Mueller matrix M44 element images, respectively.

Mueller matrix imaging of electrospun ultrafine fibers for morphology detection.

In the fields of tissue engineering, drug delivery, and filtering material, electrospun ultrafine fibers with micropores have important applications. A scanning electron microscope (SEM) is typically used to observe the microstructure of ultrafine fibers, but SEM has disadvantages, such as small field of vision, high cost, and ionization damage. Given this, 16 (4×4) full transmission Mueller matrices of electrospun fibers with three different morphologies, i.

[A correction method for calculating resistance of Westerhof 's resistor].

The objective of the mock circulatory system (MCS) is to construct the characteristics of cardiovascular hemodynamics. Westerhof 's resistor that often regarded as the laminar flow resistance in the MCS, is commonly used to simulate the peripheral resistance of the cardiovascular system. However, the theoretical calculation value of fluid resistance of the Westerhof 's resistor shows distinguished difference with the actual needed value.

A Comprehensive Method for Accurate Strain Distribution Measurement of Cell Substrate Subjected to Large Deformation.

Cell mechanical stretching is a fundamental technique commonly used in cardiovascular mechanobiology research. Accordingly, it is crucial to measure the accurate strain field of cell substrate under different strains. Digital image correlation (DIC) is a widely used measurement technique, which is able to obtain the accurate displacement and strain distribution.

A Strain Feedback Compensation Method during Cell Tensile Experiments.

Cell tensile technique is an important and widely used tool in cell mechanical research. However, the strain control condition in traditional tensile experiments is not satisfied and would result in big errors. These strain errors will seriously impact the experimental accuracy and decrease the reliability and comparability of experimental results.

A Strain Feedback Compensation Method during Cell Tensile Experiments.

Cell tensile technique is an important and widely used tool in cell mechanical research. However, the strain control condition in traditional tensile experiments is not satisfied and would result in big errors. These strain errors will seriously impact the experimental accuracy and decrease the reliability and comparability of experimental results.

Fabrication of Aligned Conducting PPy-PLLA Fiber Films and Their Electrically Controlled Guidance and Orientation for Neurites.

Electrically conductive biomaterial scaffolds have great potential in neural tissue regeneration. In this work, an aligned conductive fibrous scaffold was prepared by electrospinning PLLA on rotating collector and chemical oxidation polymerization of pyrrole (PPy) codoped with poly(glutamic acid)/dodecyl benzenesulfonic acid sodium. The characterization results of composition, structure and mechanics of fiber films show that the existence of weak polar van der Waals' force between PPy coating and PLLA fibers.

Fabrication of Eu-doped Gd(OH)3 Nanorods with Enhanced Magnetic- Resonance and Luminescence Imaging.

Background: Multimodal bio-imaging is a new technique with more than one imaging modality. Eu3+ doping can tailor the multi-functions of Gd-based nanorods (NRs) to obtain the resolution the imaging at the cellular level. Silk fibroin with His and Lys can induce to fabricate metal compounds particles.

Physiological pulsatile flow culture conditions to generate functional endothelium on a sulfated silk fibroin nanofibrous scaffold.

Many studies have demonstrated that in vitro shear stress conditioning of endothelial cell-seeded small-diameter vascular grafts can improve cell retention and function. However, the laminar flow and pulsatile flow conditions which are commonly used in vascular tissue engineering and hemodynamic studies are quite different from the actual physiological pulsatile flow which is pulsatile in nature with typical pressure and flow waveforms. The actual physiological pulsatile flow leading to temporal and spatial variations of the wall shear stress may result in different phenotypes and functions of ECs.

Fabrication and neuron cytocompatibility of iron oxide nanoparticles coated with silk-fibroin peptides.

Neuro-cytotoxicity of iron oxide nanoparticles (NPs) need to be considered. In this paper, magnetic Fe3O4 NPs are synthesized via a bio-mineralization process using silk fibroin (SF) as template. The prepared NPs with SF (SF-NPs) have more uniform grain size, better stability in weakly alkaline solution and higher saturation magnetization (about 82 emu/g) than pure NPs.

Synthesis and neuro-cytocompatibility of magnetic Zn-ferrite nanorods via peptide-assisted process.

In order to obtain magnetic nanorods (MNRs) with the neuro-cytocompatibility, silk-fibroin (SF)-coated Zn-ferrite NRs are successfully prepared via a mineralization process, and their saturation magnetization is 32emu g(-)(1). After the mineralization of 2d and 4d in the mixed solution of the concentrations of 15w/w% SF and 0.01M HCl, the lengths of NRs are ∼220nm and ∼2μm, respectively.

Synthesis and cellular compatibility of Co-doped ZnO particles in silk-fibroin peptides.

Co-doped ZnO particles were successfully prepared via a facile biomineralization process in the template of silk-fibroin (SF) peptides at room temperature, and SF peptides were coated onto the surface of particles. The ratio of Zn/Co in reactive solution could substantially influence the morphology of as-prepared particles, and the rough spherical particles including some nanoparticles of 50 nm diameters could be obtained at 4:1 ratio of Zn/Co. The saturation magnetization of SF-coated Co-ZnO particles was 8.

The influence of delayed compressive stress on TGF-β1-induced chondrogenic differentiation of rat BMSCs through Smad-dependent and Smad-independent pathways.

Mechanical stimuli play important roles in regulating chondrogenic differentiation, but seldom studies have focused on when and how mechanical stimuli should be initiated. We have previously shown that Col2α1 mRNA was increased by delayed dynamic compressive stress initiated at the 8th day of chondrogenic culture. The current work is to further study the possibility of using delayed mechanical stress to relay chondrogenesis initiated by exogenous TGF-β1.

Hydrostatic pressures promote initial osteodifferentiation with ERK1/2 not p38 MAPK signaling involved.

Mechanical stress has been considered to be an important factor in bone remodeling and recent publications have shown that mechanical stress can regulate the direction of stem cell differentiation. The exact mechanobiological effects of pressure on initial osteodifferentiation of mesenchymal stem cells (MSCs) have not been determined. These mechanobiological mechanisms may be important both in biological responses during orthodontic tooth movement and in the development of new mechanobiological strategies for bone tissue engineering.

[Facial expression recognition based on feature selection by quadratic mutual information].

To solve the problem of imprecise positioning of feature point and of the feature data redundancy in facial expression recognition by active appearance models (AAM), the automatic adjustment of initial model for AAM fitting is proposed in this paper. The specific aims are to improve the precision of positioning and to more effectively reflect the variation of expressions by acquired features. The problem of feature selection is resolved by adopting quadratic mutual information and reducing the feature dimension.