Publications by authors named "Yuanshun Huang"
Article Synopsis
- The study aimed to identify risk factors for empyema related to pulmonary abscesses by analyzing clinical data and CT imaging of 101 patients.
- The analysis revealed that 24.8% of patients with pulmonary abscesses developed empyema, with factors like male gender, diabetes, and large abscess size being significant.
- Key independent risk factors for empyema included transpulmonary fissure abscesses, diabetes, abscesses larger than 5 cm, and pleuritic symptoms.
Purpose: Reporting of adverse events (AEs) in clinical trials is critical to understanding treatment safety, but data on AE accuracy are limited. This study sought to determine the accuracy of AE reporting for pediatric acute myeloid leukemia clinical trials and to test whether an external electronic data source can improve reporting.
Methods: Reported AEs were evaluated on two trials, Children's Oncology Group AAML03P1 and AAML0531 arm B, with identical chemotherapy regimens but with different toxicity reporting requirements.
While most children receive acute myeloid leukemia (AML) chemotherapy as inpatients, there is variability in timing of discharge after chemotherapy completion. This study compared treatment-related morbidity, mortality and cumulative hospitalization in children with AML who were discharged after chemotherapy completion (early discharge) and those who remained hospitalized. Chart abstraction data for 153 early discharge-eligible patients enrolled on a Children's Oncology Group trial were compared by discharge strategy.
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