Publications by authors named "Yuanpiao Ni"
Article Synopsis
- Ankylosing spondylitis (AS) is a chronic condition characterized by inflammation of the spine and sacroiliac joints, leading to potential delays in diagnosis and treatment due to its non-specific early symptoms, underscoring the need for new biomarkers.
- Two datasets (GSE73754 and GSE25101) were analyzed to identify key genes related to AS, using methods like differential expression analysis and LASSO regression, which resulted in the discovery of five significant genes (ACSL1, SLC40A1, GZMM, TRIB1, XBP1) that showed strong diagnostic potential.
- The study also revealed correlations between these genes and immune cell infiltration as well as clinical indicators, with notable links between
The gut microbiota has been associated with primary Sjogren's syndrome (pSS), yet the biological implications of these associations are often elusive. We analyzed the fecal microbiota through 16S rRNA gene amplification and sequencing in 30 patients with pSS and 20 healthy controls (HCs); At the same time, the fecal metabolome was characterized by ultrahigh-performance liquid chromatography-mass spectrometry. In addition, correlation analyses of microbiota and metabolome data were performed to identify meaningful associations.
View Article and Find Full Text PDFThe aim of this study is to evaluate the clinical efficacy of vitamin D (VitD) supplementation in terms of response to treatment and improvement of disease activity in rheumatoid arthritis (RA). This study analyzed 1180 RA patients' records treated at Mianyang Central Hospital from February 2015 to July 2019. The patients were allocated into VitD group and control group based on their medical regimens.
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