ASCOD phenotyping of acute vertebrobasilar artery occlusion treated by mechanical thrombectomy: insight from the PERSIST registry.

Objective: Determining the underlying etiology of acute vertebrobasilar artery occlusion (VBAO) is crucial for selecting an appropriate treatment approach. The authors aimed to investigate the distribution of etiology and the association with functional outcomes in patients with acute VBAO who underwent endovascular treatment in which atherosclerosis, small-vessel disease, cardiac pathology, other causes, and dissection (ASCOD) phenotyping was used.

Methods: A retrospective study was conducted at 21 centers in China, involving patients with VBAO who received endovascular treatment within 24 hours of the estimated occlusion time.

Effect of the Early Administration of Selective Serotonin Reuptake Inhibitors on the Time Course of Poststroke Fatigue: A 2-Year Longitudinal Study.

Background: Poststroke fatigue (PSF) is a dynamic process over time. Current evidence for interventions for PSF is limited. Our study investigated the effects of selective serotonin reuptake inhibitors (SSRIs) on the time course of PSF.

Obesity and Poststroke Fatigue: A 2-Year Longitudinal Study.

Introduction: Obesity is associated with fatigue in many diseases, but the correlation between obesity and poststroke fatigue (PSF) is unclear. The study aimed to investigate the relationship between body mass index (BMI) and the occurrence of and recovery from PSF.

Methods: Within 3 days of the onset of ischemic stroke, patients were consecutively recruited.

Influence of procedure time on outcome and hemorrhagic transformation in stroke patients undergoing thrombectomy.

Background And Purpose: Data on procedure time (PT) for mechanical thrombectomy (MT) are scarce. Moreover, the relationship among PT, postprocedural hemorrhagic transformation (HT), and functional outcomes in MT patients remains unclear. We investigated whether postprocedural HT mediated the relationship between PT and functional outcomes in patients with stent-retriever thrombectomy.

Adsorption removal of tetracycline from aqueous solution by anaerobic granular sludge: equilibrium and kinetic studies.

High concentration animal wastewater is often contaminated by tetracycline and an upflow anaerobic sludge bioreactor (UASB) with granular sludge is often used to treat the wastewater. The investigation of the adsorption process of tetracycline on anaerobic granular sludge during anaerobic digestion of animal wastewater will increase the understanding of antibiotics behavior in the UASB reactor. In this study, the effects of initial pH, humic acid concentration, and temperature on the removal of tetracycline by anaerobic granular sludge from aqueous solution were investigated using the batch adsorption technique in 100 mL flasks with 75 mL of work volume.

[Anaerobic digestion of animal manure contaminated by tetracyclines].

Anaerobic digestion of pig manure spiked with tetracycline (TC) and chlortetracycline (CTC) and the degradation of the two antibiotics during the anaerobic digestion at 35 degrees C were investigated. The results indicate that propionate was the main volatile fatty acid produced during the anaerobic digestion followed by acetate. Compared with the CTC addition, TC + CTC addition showed obvious inhibitory effect on the hydrolysis and acidification of easily digestible organic components of pig manure.

Characterization of organic matter degradation during composting of manure-straw mixtures spiked with tetracyclines.

The objective of this study was to investigate humification and mineralization of manure-straw mixtures contaminated by tetracyclines during composting. Hen manure, pig manure and rice straw were used as the raw materials. The manure-straw mixtures were spiked with tetracycline, chlortetracycline, and oxytetracycline at the concentration of 60 mg/kg dry matter.

[The effects of tetrandrine on activity of collagenase derived from human hypertrophic scar].

Objective: To observe the effect of tetrandrine on activity of collagenase derived from human hypertrophic scar for the sake of clarifying the mechanism as tetrandrine acting on scar.

Methods: The experimental concentration was controlled below that of cell proliferation inhibited, SDS-PAGE electrophoresis was adopted to separate collagenase from extracellular matrix, and then activated by trypsin analyzed the activity of collagenase with density scanning apparatus. At the same time quantity of extracellular collagen was measured using improved chloraseptine T oxidizing assay, moreover analyzed correlation between activity of collagenase and quantity of extracellular collagen.