Publications by authors named "Yuanlinhan Zhou"
Front Pharmacol
July 2020
Article Synopsis
- Metformin shows promise in reducing fibrosis and improving outcomes in glaucoma surgery, as observed in a study involving SD rats.
- The drug appears to lower oxidative stress and fibrosis in human conjunctival fibroblasts by influencing macrophage behavior.
- Mechanisms include the involvement of organic cation transporters (OCTs) and the activation of the AMPK/Nrf2 pathway, suggesting a complex anti-fibrotic action of metformin.
