The Impact of Titanium Hydroxyapatite Doping on the Mechanical and Biological Properties of Photocured Resin.

Photocured resin materials are widely used in various fields, such as 3D printing, medical applications, and dentistry. However, the strength, wear resistance, and antibacterial properties of photocured resin are relatively limited, rendering it susceptible to potential failures. In this recent study, photocured composite resins incorporating titanium-doped hydroxyapatite (Ti-HAp) were fabricated to investigate their mechanical and biological properties.

Prediction of mechanical ventilation outcome by early abdominal-visceral-blood-flow-and-function score in critically ill patients after cardiopulmonary bypass in the ICU: A prospective observational study.

Background: Abdominal organs are important organs that sense and respond to ischemia and hypoxia, but there are few evaluation methods.We use ultrasonography to evaluate abdominal organ function and blood flow in patients with mechanical ventilation (MV) after cardiopulmonary bypass and to obtain a semiquantitative score for abdominal organ function and blood flow.

Methods: Patients with cardiopulmonary bypass in the Critical Care Department of Peking Union Medical College Hospital in China from March to July 2021 were enrolled in this prospective observational study.

The level of partial pressure of carbon dioxide affects respiratory effort in COVID-19 patients undergoing pressure support ventilation with extracorporeal membrane oxygenation.

Background: Patients with COVID-19 undergoing pressure support ventilation (PSV) with extracorporeal membrane oxygenation (ECMO) commonly had high respiratory drive, which could cause self-inflicted lung injury. The aim of this study was to evaluate the influence of different levels of partial pressure of carbon dioxide(PaCO) on respiratory effort in COVID-19 patients undergoing PSV with ECMO.

Methods: ECMO gas flow was downregulated from baseline (respiratory rate < 25 bpm, peak airway pressure < 25 cm HO, tidal volume < 6 mL/kg, PaCO < 40 mmHg) until PaCO increased by 5 - 10 mmHg.

Atomistic Insight into Grain Boundary Deformation Induced Strengthening in Layer-Grained Nanocrystalline Al.

The brittle nature of nanocrystalline metals presents a significant challenge to their widespread application. Extensive efforts have been undertaken to develop materials with high strength and good ductility. In this study, we have discovered a new type of nanocrystalline metal, namely, layer-grained Al, which exhibits both high strength and good ductility owing to its enhanced strain hardening ability as revealed by molecular dynamics simulation.

Elevation of the head of bed reduces splanchnic blood flow in patients with intra-abdominal hypertension.

Background: Elevation of the head of bed (HOB) increases intra-abdominal pressure (IAP), but the effect of body position on abdominal splanchnic perfusion is not clear. The current study aimed to evaluate the effect of body position on the superior mesenteric artery (SMA) and the celiac artery (CA) blood flow by Doppler ultrasound in mechanically ventilated patients with intra-abdominal hypertension (IAH).

Methods: This prospective cohort study included 53 mechanically ventilated patients with IAH.

High respiratory effort decreases splanchnic and peripheral perfusion in patients with respiratory failure during mechanical ventilation.

Purpose: This study aimed to evaluate the effects of high respiratory effort(HRE) on spleen, kidney, intestine, and peripheral perfusion in patients with respiratory failure during mechanical ventilation.

Methods: HRE was defined as a pressure muscle index (PMI) > 6 cmHO and airway pressure swing during occlusion (ΔPOCC) > 10 cmHO. Capillary refill time(CRT) and peripheral perfusion index (PPI) were determined when HRE occurred.

Elevated pulsatility index of the superior mesenteric artery indicated prolonged mechanical ventilation in patients after cardiac valve surgery.

Purpose: This study examined whether alterations in Doppler parameters of superior mesenteric artery (SMA) are associated with prolonged mechanical ventilation (PMV) in patients who underwent cardiac valve surgery.

Methods: Hemodynamic and SMA Doppler parameters were collected at intensive care unit(ICU) admission. The duration of mechanical ventilation was monitored.

Effect of Annealing Time on the Cyclic Characteristics of Ceramic Oxide Thin Film Thermocouples.

Oxide thin film thermocouples (TFTCs) are widely used in high-temperature environment measurements and have the advantages of good stability and high thermoelectric voltage. However, different annealing processes affect the performance of TFTCs. This paper studied the impact of different annealing times on the cyclic characteristics of ceramic oxide thin film thermocouples.

Resistance Index of the Superior Mesenteric Artery: Correlation With Lactate Concentration and Kinetics Prediction After Cardiac Surgery.

This study aimed to measure blood flow changes in the superior mesenteric artery (SMA), using Doppler ultrasound, in post-cardiac surgery patients, to evaluate the correlation between the SMA resistance index (SMA-RI) and lactate concentrations. The patients' basic hemodynamics, blood gas parameters and lactate concentration were collected at admission. Simultaneously, the SMA blood flow parameters were collected using Doppler ultrasound with the patients in the supine position.

Acute hyperventilation increases oxygen consumption and decreases peripheral tissue perfusion in critically ill patients.

Purpose: This study aimed to evaluate the effects of acute hyperventilation on central venous-to-arterial carbon dioxide tension difference (Pv-aCO), central venous oxygen saturation (ScvO), central venous-to-arterial CO difference/arterial-central venous O difference ratio (COGAP-Ratio), and peripheral perfusion index (PI) in hemodynamically stable critically ill patients.

Methods: Fifty-four mechanically ventilated patients were evaluated. The cardiac index, Pv-aCO, ScvO, COGAP-Ratio, PI, and arterial and venous blood gas parameters were measured in the first set of measurements.

Nanogenerator-based self-powered sensors for data collection.

Self-powered sensors can provide energy and environmental data for applications regarding the Internet of Things, big data, and artificial intelligence. Nanogenerators provide excellent material compatibility, which also leads to a rich variety of nanogenerator-based self-powered sensors. This article reviews the development of nanogenerator-based self-powered sensors for the collection of human physiological data and external environmental data.

Cross-sectional study for the clinical application of extracorporeal membrane oxygenation in Mainland China, 2018.

Background: To investigate the epidemiology and in-hospital mortality of veno-venous (VV) and veno-arterial (VA) extracorporeal membrane oxygenation (ECMO) in Mainland China throughout 2018.

Methods: Patients supported by ECMO from 1700 tertiary hospitals in 31 provinces from January 1 to December 31, 2018, were selected from the National Clinical Improvement System database.

Results: The 1700 included hospitals had 2073 cases of ECMO in 2018, including 714 VV and 1359 VA ECMOs.

Total pancreatic necrosis after organophosphate intoxication.

Cases of acute pancreatitis induced by organophosphate intoxication are encountered occasionally in clinics, but very few of them develop into severe pancreas necrosis and irreversible pancreatic function impairment. Here, we report a 47-year-old female organophosphate poisoning case after ingestion of massive insecticides; she was considered to have total necrosis and function failure of the pancreas via serum amylase test, glucose level test, and CT imaging. The patient exhibited no relief under the regular medicine treatment, which included sandostatin, antibiotics, intravenous atropine, and pralidoxime methiodide.