Effects of Patient-Controlled Epidural Analgesia on Uterine Electromyography During Spontaneous Onset of Labor in Term Nulliparous Women.

Objective: To investigate the effect of patient-controlled epidural analgesia (PCEA) on uterine electromyography (EMG) activity in term pregnant women during labor.

Methods: Nulliparous pregnant women in spontaneous term labor (N = 30) were enrolled (PCEA group, n = 20 and control group, n = 10). Five time periods (30 minutes each) were defined for noninvasive abdominal recordings and analysis of uterine EMG activity, that is, period I: before PCEA treatment with 2-cm cervical dilation; periods II to IV: each period successively at 30, 60, and 120 minutes after PCEA; and period V: second stage of labor with cervix at 10 cm dilation.

PP014. A pioneer explore of PTZ-induced eclampsia in preeclampsia rats.

Introduction: Eclampsia is the most serious state of hypertensive disorder in pregnancy, but the pathogenesis of eclampsia seizures is poorly understood.

Objectives: An eclampsia animal model was developed by PTZ injection on preeclampsia rats.

Method: Rats received endotoxin (1.