Cardiorespiratory fitness and metabolic risk in Chinese population: evidence from a prospective cohort study.

Background: Studies on the association between estimated cardiorespiratory fitness (CRF) and changes in metabolic risk in the Chinese population are limited. This study aims to examine the associations between CRF and changes in metabolic risk.

Subjects And Methods: We included 4,862 and 2,700 participants recruited from 28 provinces in the China Health and Retirement Longitudinal Study (CHARLS) in the baseline (Wave 1) and follow-up (Wave 4) analyses, respectively.

Estimated cardiorespiratory fitness and incident risk of cardiovascular disease in China.

Background: Limited evidence is available on the association between estimated cardiorespiratory fitness (e-CRF) and incidence of cardiovascular disease (CVD) in Chinese population.

Methods: A total of 10,507 adults including 5084 men (48.4%) and 5423 (51.

F···Br and F···S Heterohalogen-Bond-Directed 2D Self-Assemblies of a Benzothiadiazole Derivative.

Halogen bonding (XB) is of great importance in fabricating a two-dimensional (2D) self-assembly for its adaptive directionality. However, the XBs involving fluorine (F) have barely been studied due to the absence of an σ-hole on F. Here, 2D self-assemblies of a F-substituted 4,7-bis(5-bromo-4-dodecylthiophen-2-yl)-5,6-difluorobenzo[c][1,2,5]thiadiazole (BTZ-BrF) molecule on graphite were investigated using scanning tunneling microscopy (STM) and density functional theory (DFT) calculations.

CD14 dictates differential activation of mesenchymal stromal cells through AKT, NF-κB and P38 signals.

Mesenchymal stromal cells (MSCs) widely exist in many tissues and have multiple differentiation potential and immunomodulatory capacities. Recently, MSCs have become promising tools for the treatment of various degenerative disorders and autoimmune diseases. The properties of MSCs could be modified in different microenvironments.

[In vitro effect of combined traditional Chinese medicine (Changqing capsule) on the tachyzoites of Toxoplasma gondii].

Objective: To detect the in vitro effect of the traditional Chinese medicine on the tachyzoites of Toxoplasma gondii.

Methods: Supernatant (1.5 ml) of different doses of the traditional Chinese medicine (Changqing capsule) was collected by normal saline immersion and 2.

[Expressions of Cx43 and Skp2 in epithelial ovarian tumor and their clinical significances].

Background & Objective: Connexin 43 (Cx43), an important member of connexins family, is frequently down-regulated in neoplastic cells. It has been shown to have gap junction-dependent anti-tumor effect on various tumor cell lines. Recently, it was reported that Cx43 could inhibit tumor growth via down-regulating the expression of S-phase kinase associated protein 2 (Skp2).

[Expression of cellular FLICE inhibitory protein (cFLIP) in endometrial adenocarcinoma].

Background & Objective: Cellular FLICE inhibitory protein (cFLIP) is a new-found member of the inhibitors of apoptosis. It has been reported to be overexpressed in various human cancers. We investigated the expression of cFLIP in endometrial adenocarcinoma and its association with clinicopathological features and proliferating cell nuclear antigen-labeling index (PCNA-LI).