Portable electronic bronchoscopy for clinical application: a multi-institutional randomized instrument validation study.

Objective: Electronic bronchoscopy is routinely used for the diagnosis and treatment of lung and bronchial disorders. However, the devices used are normally large and costly. Here, we evaluated the clinical effectiveness of a portable electronic bronchoscope produced by Zhejiang UE Medical Corp.

Migration of ingested sharp foreign body into the bronchus: a case report and review of the literature.

Background: Foreign body ingestion is a common emergence in gastroenterology. Foreign bodies are most likely to be embedded in the esophagus. The sharp ones may penetrate the esophageal wall and lead to serious complications.

Validation of novel automatic ultra-wideband radar for sleep apnea detection.

Background: To validate the accuracy of ultra-wideband (UWB) wireless radar for the screening diagnosis of sleep apnea.

Methods: One hundred and seventy-six qualified participants were successfully recruited. Apnea-hypopnea index (AHI) results from polysomnography (PSG) were reviewed by physicians, while the radar device automatically calculated AHI values with an embedded chip.

Serum levels of IGFBP7 are elevated during acute exacerbation in COPD patients.

Objective: The purpose of this study was to explore the insulin-like growth factor binding protein 7 (IGFBP7) level in the serum of chronic obstructive pulmonary disease (COPD) patients during acute exacerbation (AE).

Methods: The study population consisted of 47 AECOPD patients, including 25 patients enrolled between January 2011 and February 2011 (the first group) and 22 patients enrolled from December 2011 to August 2012 (the second group) and 29 healthy controls. Chemiluminescence-linked immunoassay was used to detect serum IGFBP7 levels.

[Determination of volatile organic compounds in lung cancer cell lines and lung cancer tissue].

Objective: To identify the volatile organic compounds (VOCs) in lung cancer tissue and lung cancer cell lines.

Methods: The lung cancer tissue samples from 18 patients were cultured and 4 lung cell lines (A549, NCI-H446, SK-MES-1, BEAS-2B) were also included in the study. Air samples in the headspace of culture flasks were analyzed for VOCs with solid-phase micro-extraction and gas chromatography-mass spectroscopy technique (SPME-GC/MS).

[Measurement of exhaled volatile organic compounds in lung cancer patients].

Objective: to study the characteristics of volatile organic compounds (VOCs) in exhaled breath of lung cancer patients, and therefore to explore its use in the diagnosis of the disease.

Methods: from February 2007 to September 2009, 55 patients with lung cancer, 21 patients with benign lung diseases and 30 healthy controls were enrolled in our study. The VOCs in exhaled breath were detected by the SPME (solid phase microextraction)-GC (gas chromatography) system.