Publications by authors named "Yuanhong Zhu"

Article Synopsis
  • - Bacillus thuringiensis (Bt) produces insecticidal proteins, but these proteins can lose potency when exposed to UV radiation, which is a challenge for microbial insecticides.
  • - Researchers deleted the mclX gene in the Bt strain KN11, leading to better UV resistance and preserved insecticidal activity without negatively affecting protein production.
  • - The study highlights a successful genetic modification method that helps to protect insecticidal crystals in Bt strains, enhancing their effectiveness in commercial applications.
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Antimicrobial acroautophagy/autophagy plays a vital role in degrading intracellular pathogens or microbial molecules in host-microbe interactions. However, microbes evolved various mechanisms to hijack or modulate autophagy to escape elimination. Vector-transmitted phloem-limited bacteria, Liberibacter (.

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This study investigated the reversible and irreversible membrane fouling behavior of micro polluted water by ozone/powdered activated carbon (PAC)/ultrafiltration treatment. The results indicated that PAC mainly adsorbed low-molecular weight organics and reduced the irreversible fouling resistance in ultrafiltration, while there existed a threshold PAC dosage for total and reversible fouling resistance alleviation. Ozone at low doses exerted little effect on membrane fouling alleviation, while higher doses controlled total and reversible fouling by reducing macromolecular biopolymers and humic-like substances.

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This study investigated the ultrafiltration (UF) membrane fouling mechanism of intracellular organic matter (IOM) from Chlorella vulgaris (CV) and Microcystis aeruginosa (MA). Both CV- and MA-IOM caused severe membrane fouling during UF; however, there were significant differences in the membrane fouling by these two materials. Neutral hydrophilic (N-HPI) compounds were the organics that caused the most severe membrane fouling during CV-IOM filtration, whereas the MA-IOM membrane fouling was induced by mainly hydrophobic (HPO) organics.

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Plant pathogens deliver virulence effectors into plant cells to modulate plant immunity and facilitate infection. Although species-specific virulence effector screening approaches have been developed for several pathogens, these assays do not apply to pathogens that cannot be cultured and/or transformed outside of their hosts. Here, we established a rapid and parallel screening assay, called the virus-induced virulence effector (VIVE) assay, to identify putative effectors in various plant pathogens, including unculturable pathogens, using a virus-based expression vector.

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Gastrointestinal (GI) diffuse large B-cell lymphoma (DLBCL) is one of the frequently reported histologic subtypes of non-Hodgkin lymphoma (NHL) that occur in the GI tract. However, the presentation of quite different clinical manifestations, morphologic characteristics, immunophenotypes, and molecular biologic features is challenging for its diagnosis. Herein, we describe a rare case of primary colorectal DLBCL that occurred in a 59-year-old immunocompetent Chinese female who attended our respiratory clinic for the third time with an asymptomatic pleural effusion and pleural thickening.

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Descending necrotizing mediastinitis is a severe infection of the mediastinum. This syndrome manifests as fever and chest pain following cough and sputum production. A 49-year-old woman presented with fever and a 14-day history of pneumonia.

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Eco-agricultural systems aim to reduce the use of chemical fertilizers in order to improve sustainable production and maintain a healthy ecosystem. The aim of this study was to explore the effects of rice-frog farming on the bacterial community and N-cycling microbes in paddy rhizosphere soil. This experiment involved three rice cultivation patterns: Conventionally cultivated rice (CR), green rice-frog farming (GR), and organic rice-frog farming (OR).

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Lung cancer is one of the most common malignant tumors and also the leading cause of cancer-related deaths in the world. Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKI), such as gefitinib, have been used in the therapy of lung cancer. However, the acquisition of drug resistance is a major limitation in the clinical efficiency of EGFR-TKIs.

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Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR‑TKI) have been used as a standard therapy for patients with lung cancer with EGFR‑activating mutations. Epithelial‑mesenchymal transition (EMT) has been reported to be associated with the development of EGFR‑TKI resistance, which limits the clinical efficacy of EGFR‑TKI. Therefore, investigating the resistance‑associated mechanism is required in order to elucidate an effective therapeutic approach to enhance the sensitivity of lung cancer to EGFR‑TKI.

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Asthma is a heterogeneous disease characterized by symptoms of chronic inflammation and airway structural and functional changes. It affects about 300 million people worldwide and causes 250 000 deaths annually, but its symptoms can be greatly relieved by regular use of inhaled glucocorticoids (GCs). GCs exert their function through interacting with glucocorticoid receptors (GRs).

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Objective: To establish the microfold (M)-like cell model in vitro and identify M-like cells through detecting the capacity of transporting fluorescent beads and the levels of the associated genes, and to observe the effects of lymphocyte culture supernatants stimulated by concanavalin A (Con A) from different lymphoid tissues on the differentiation of Caco2 cells into M-like cells.

Methods: The isolated lymphocytes of Peyer's patch (PP), mesenteric lymph node (MLN) and spleen (Sp) were incubated with 3 μg/mL Con A for 3 days. The culture supernatants were collected and co-cultured with Caco2 cells.

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Objective: To explore the effect of qidong huoxue decoction (QHD) on inflammatory factors and Toll-like receptor (TLR4) mRNA expressions in acute lung injury (ALI) rats.

Methods: Totally 50 healthy male SD rats were randomly divided into the blank control group, the lipopolysaccharide (LPS) model group, low, middle, high dose QHD groups according to body weight, 10 rats in each group. Rats in low, middle, high dose QHD groups were intragastrically administered with QHD at 4, 8, and 16 mL/kg 24, 12 h before modeling and 12 h after modeling, respectively.

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Objective: To investigate the amounts of extractable organic nitrogen (EON), and the relationships between EON and total extractable nitrogen (TEN), especially the amino acids (AAs) adsorbed by soils, and a series of other hydrolyzed soil nitrogen indices in typical land use soil types from southeast China. Under traditional agricultural planting conditions, the functions of EON, especially AAs in the rhizosphere and in bulk soil zones were also investigated.

Methods: Pot experiments were conducted using plants of pakchoi (Brassica chinensis L.

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Regression models for predicting total streamflow (TSF), baseflow (TBF), and storm runoff (TRO) are needed for water resource planning and management. This study used 54 streams with >20 years of streamflow gaging station records during the period October 1971 to September 2001 in Pennsylvania and partitioned TSF into TBF and TRO. TBF was considered a surrogate of groundwater recharge for basins.

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