Allicin inhibits the invasion of lung adenocarcinoma cells by altering tissue inhibitor of metalloproteinase/matrix metalloproteinase balance via reducing the activity of phosphoinositide 3-kinase/AKT signaling.

Allicin, the main active principle associated with chemistry, has various antitumor activities. However, to the best of our knowledge, there is no available information to address the anti-invasive effect and associated mechanism in lung adenocarcinoma. In the present study, cell viability assay, cell adhesion assay, western blot analysis, Transwell migration and invasion assays and reverse transcription-quantitative polymerase chain reaction were performed.

Time evolution and energy deposition for ion clusters injected into magnetized two-component plasmas.

A two-dimensional particle-in-cell simulation model is proposed to study the time evolution and energy deposition for ion clusters injected into magnetized two-component plasmas. The injection of an isolated ion cluster is studied in the case of weak and strong magnetic fields. For strong magnetic fields, the ions tend to deposit their energy smoothly along the trajectory of the cluster, due to the confinement by the strong magnetic fields.

Wake effect and stopping power for a charged ion moving in magnetized two-component plasmas: two-dimensional particle-in-cell simulation.

A two-dimensional particle-in-cell (PIC) model is proposed to study the wake field and stopping power induced by a nonrelativistic charged particle moving perpendicular to the external magnetic field in two-component plasmas. The effects of the magnetic field on the wake potential and the stopping due to the polarization of both the plasma ions and electrons are discussed. The velocity fields of plasma ions and electrons are investigated, respectively, in the weak and strong magnetic field cases.

Simulation of dust particles in dual-frequency capacitively coupled silane discharges.

The behavior of nanoparticles in dual-frequency capacitively coupled silane discharges is investigated by employing a one-dimensional self-consistent fluid model. The numerical simulation tries to trace the formation, charging, growth, and transport of dust particles during the discharge, under the influences of the high- and low-frequency electric sources, as well as the gas pressure. The effects of the presence of the nanoparticles and larger anions on the plasma properties are also discussed, especially, for the bulk potential, electron temperature, and densities of various particles.

Dynamic polarization and energy dissipation for charged particles moving in magnetized two-component plasmas.

Energy losses of test particles in magnetized two-component plasmas are investigated within the framework of the linearized Vlasov-Poisson theory, taking into account the dynamic polarization effects of both the plasma ions and electrons. General expressions of the potential and stopping power are obtained and calculations are performed for protons in a magnetized hydrogen plasma. The influences of the magnetic field, the angle between the proton velocity and magnetic field, and certain plasma parameters on the stopping power are studied.