Publications by authors named "Yuanhang Kong"

saponins (PNS) have been reported to have good anti-inflammatory effects. However, the anti-inflammatory effect mechanism in rheumatoid arthritis (RA) remains unknown. The focus of this research was to investigate the molecular mechanism of PNS in the treatment of RA.

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Article Synopsis
  • Silicate-substituted calcium phosphate (Si-CaP) ceramics are effective materials for bone grafts due to their favorable biological properties but suffer from weak mechanical strength and poor structure control.
  • * Researchers developed a new porous 3D printed Si-CaP scaffold using digital light processing (DLP) technology, which improved its mechanical properties, structural uniformity, and internal permeability.
  • * The 3D printed Si-CaP scaffold enhanced bone cell activity and mineralization while enabling sustained release of essential ions, making it a promising option for better bone tissue engineering and regeneration.
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Silicon-substituted calcium phosphate (Si-CaP) is a promising bioactive material for bone tissue engineering. The mechanism of Si-CaP regulates osteogenic-angiogenic coupling during bone regeneration has not been fully elucidated. In this study, we screened the targets of Si-CaP and osteogenic-angiogenic coupling.

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Recent studies have shown that the differentiation of bone marrow mesenchymal stem cells (BMSCs) into osteogenic lineages can promotes bone formation and maintains bone homeostasis, which has become a promising therapeutic strategy for skeletal diseases such as osteoporosis. Fructus Ligustri Lucidi (FLL) has been widely used for the treatment of osteoporosis and other orthopedic diseases for thousands of years. However, whether FLL plays an anti-osteoporosis role in promoting the osteogenic differentiation of BMSCs, as well as its active components, targets, and specific molecular mechanisms, has not been fully elucidated.

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Background: During minimally invasive spine surgery, nerve root decompression is challenging due to the anatomical division and uncertainty in lumbar lateral recess (LLR).

Objectives: To evaluate the outcome and safety of foraminoplasty using percutaneous transforaminal endoscopic decompression (PTED) (performed with an aid of a trephine) in the treatment of lumbar lateral recess stenosis (LLRS).

Material And Methods: All operations were performed under local anesthesia and in prone position.

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