Assessing different models to predict the growth and development of pepper plants under water deficits.

To construct pepper development simulation models under drought, experiments of water capacities of 45-55%, 55-65%, 65-75% or 75-85% and exposure (2, 4, 6 or 8 d) (Exp. 1 & 2), of 50-60%, 60-70% or 70-80% and exposure (3, 5, and 7 d) (Exp. 3) were conducted with "Sanying" pepper.

The impact of intra-annual temperature fluctuations on agricultural temperature extreme events and attribution analysis in mainland China.

Daily temperature variations, which tend to exhibit non-constant and non-linear patterns, are often characterized by intra-annual fluctuations that cause severe and frequent extreme temperature events that have an enormous impact on agricultural production. However, the quantitative relationship between intra-annual temperature fluctuations and extreme agricultural temperatures remains unclear. We aimed to investigate intra-annual temperature fluctuation changes based on daily meteorological data in nine agricultural regions across China from 1960 to 2022 and quantify the impact of temperature fluctuations on extreme agricultural temperatures during crop growth periods.

Prediction Value of Initial Serum Levels of SERPINA3 in Intracranial Pressure and Long-Term Neurological Outcomes in Traumatic Brain Injury.

Traumatic brain injury (TBI) is a severe neurological condition characterized by inflammation in the central nervous system. SERPINA3 has garnered attention as a potential biomarker for assessing this inflammation. Our study aimed to explore the predictive value of postoperative serum SERPINA3 levels in identifying the risk of cerebral edema and its prognostic implications in TBI.

Correlation of iron deficiency indexes with Eradication and Recurrence of Helicobacter Pylori Infection in Children.

Objective: To explore the correlation of iron deficiency (ID) indexes with eradication and recurrence of Helicobacter pylori (Hp) infection in children.

Methods: This is a clinical comparative study. One hundred and twenty-six children who were first diagnosed as Hp infection in Baoding Children's Hospital (Hp infection group); and the control group included 200 children without Helicobacter Pylori infection (negative stool Hp antigen test and/or 13C-urea breath test) in local region at the same time from January 2020 to January 2022.

Highly precise timing alignment of multi-wavelength interleaved cavity-less pulse sources with FROG.

Strictly uniform time interval between adjacent channels is a crucial requirement for the multi-wavelength interleaved (MWI) pulse sources, which difficult alignment can be easily solved by what we believe to be our novel method based on frequency-resolved optical gating (FROG). By utilizing highly precise measurements from FROG, which provide fully two-dimensional information of the pulses in time and frequency domain, we can intuitively identify the time mismatches between different channels in the MWI pulse sources. This enables us to directly align the timing of each channel with sub-picosecond resolution at the first time.

Role of METTL3 in Aerobic Glycolysis of Glioma by Regulating m6A/miR-27b-3p/PDK1.

Methyltransferase like 3 (METTL3) has been reported to be dysregulated in glioma. However, its role in aerobic glycolysis of glioma remains unknown. This study was conducted to explore the molecular mechanism by which METTL3 regulates aerobic glycolysis of glioma and provide novel targets for the treatment of glioma.

Netrin-1 upregulates GPX4 and prevents ferroptosis after traumatic brain injury via the UNC5B/Nrf2 signaling pathway.

Aim: We aimed to investigate the regulatory role of Netrin-1 (NTN1) in ferroptosis after traumatic brain injury (TBI) in mice.

Methods: We assessed the expression pattern of NTN1 by RT-PCR, western blot, and immunofluorescence after establishing the TBI model in mice. After treatment with NTN1 shRNA or recombinant NTN1, we determined the biochemical and morphological changes associated with ferroptosis and netrin-1-related pathways.

Effects of inflammatory cytokines on eradication and recurrence of Helicobacter pylori infection in children.

Objectives: To study the correlation of eradication and recurrence with IL-1 β, IL-6 and TNF-α levels in children with Helicobacter pylori (Hp) infection.

Methods: Children confirmed with Hp infection (n = 153) in our hospital from January to June 2019 and successfully followed up for one year were selected as the study subjects, and 73 healthy children of the same period were selected as the control group. The levels of IL-1 β, IL-6 and TNF-α in children confirmed with Hp infection and healthy children were detected, respectively.

The Prognostic Value of Deleted in Colorectal Cancer (DCC) Receptor and Serum Netrin-1 in Severe Traumatic Brain Injury.

Traumatic brain injury (TBI) is a common neurological disease. Netrin-1 and deleted in colorectal cancer (DCC) receptor are potential biomarkers associated with nerve regeneration and immune regulation. We aimed to investigate the ability of the DCC receptor and Netrin-1 to predict a high ICP level after operation in severe traumatic brain injury and their prognostic significance.

Effects of lymphocyte, C-reactive protein and prealbumin levels on clinical typing and course of disease in children infected with novel coronavirus.

Objectives: To investigate the effects of lymphocyte (LY), C-reactive protein (CRP) and prealbumin (PA) levels on the clinical typing and course of disease in children infected with novel coronavirus (2019-nCoV) at the early stage.

Methods: A total of 140 children with 2019-nCoV infection diagnosed in Shijiazhuang People's Hospital and Hebei Provincial Chest Hospital from January 2021 to February 2021 were selected for this study. According to the clinical symptoms, laboratory results and imaging examination, the children were divided into asymptomatic infection group, mild infection group and common infection group.

Correlation between helicobacter pylori infection and iron deficiency in children.

Objectives: To investigate the correlation between Helicobacter pylori (Hp) infection and Iron deficiency (ID) in children.

Methods: This cross-sectional study was conducted at Baoding Children's Hospital from January 2018 to December 2019. A total of one thousand children who came to our hospital for physical examination and met the inclusion criteria were continuously included in this study.

Effect of Anti-Hp treatment on nutritional status of children with Helicobacter Pylori-Positive Gastritis and its clinical significance.

Objectives: To evaluate the outcome of anti-HP treatment on the nutritional status of children with Helicobacter pylori-positive gastritis.

Methods: Sixty children with Helicobacter pylori-positive gastritis admitted to our hospital from June 2018 to June 2020 were selected as the experimental group, and 60 healthy normal people (Hp negative) were selected as the control group. The experimental group were given anti-HP treatment, and the improvement of their clinical symptoms after treatment and the changes of nutritional indexes such as hemoglobin and serum ferritin were observed one year after treatment.

Mutation and Copy Number Alterations Analysis of KIF23 in Glioma.

In glioma, kinesin family member 23 (KIF23) is up-regulated and plays a vital role in oncogenesis. However, the mechanism underlying KIF23 overexpression in malignant glioma remains to be elucidated. This study aims to find potential causes of KIF23 high expression at genome level.

Curative effect of Omeprazole under different treatment courses in treatment of children with PU and HP infection and its influence on inflammatory factors.

Objective: To compare curative effect and safety of omeprazole under different treatment courses in treatment of children with peptic ulcer (PU, diameter≤1.0cm) and helicobacter pylori (HP) infection and its influence on inflammatory cytokines.

Methods: The study was a randomized controlled study and conducted at Baoding children's hospital from June 2015 to June 2018.

Effectiveness of gamma globulin combined with methylprednisolone sodium succinate in severe hand foot mouth disease - Baoding Children's Hospital, China.

Objective: To determine the curative effect of gamma globulin combined with methylprednisolone sodium succinate on paediatric patients with severe hand-foot-mouth disease and analyse its influence on cardio-pulmonary functions.

Methodology: Eighty paediatric patients with severe hand-foot-mouth diseases (HFMD) treated in Baoding Children's Hospital, Key Laboratory of Clinical Research on Respiratory Digestive Disease from January 2015 to January 2017 were selected. This study was designed as a case control study with equally dividing patients into test and control groups through random digital method.

Analysis of Eradication, Recurrence and Levels of 25-hydroxyvitamin D and Interleukin-1β in paediatric patients with Helicobacter Pylori Infection-related Gastritis.

Objective: To study whether the levels of 25-hydroxyvitamin D (25-(OH)D) and Interleukin-1β (IL-1β) are correlated to the eradication and recurrence of helicobacter pylori (Hp) in paediatric patients with Hp infection-related gastritis.

Methods: A total of 142 paediatric patients with Hp infection-related gastritis from November 2017 to March 2018 in Baoding Children's Hospital were selected as study subjectswere selected as study subjects and were followed up for one year. Paediatric patients were grouped and analyzed according to the effect of follow-up treatment and recurrence.

Relationship between myocardial enzyme levels, hepatic function and metabolic acidosis in children with rotavirus infection diarrhea.

Objective: To investigate the relationship between myocardial enzymes, liver function and metabolic acidosis in children with rotavirus infection diarrhea.

Methods: The data of 70 children with infectious diarrhea treated in Baoding Children's Hospital, China, from October 2017 to April 2018 were retrospectively studied. The antigen of rotavirus in feces was positive by colloidal gold method.

Risk factors for recurrence of Helicobacter pylori infection after successful eradication in Chinese children: A prospective, nested case-control study.

Background: Limited research has been published on the recurrence of Helicobacter pylori infection and risk factors in Chinese children. Our study aimed to identify risk factors for Helicobacter pylori infection recurrence after successful eradication in children.

Materials And Methods: A prospective, nested case-control study was performed.

Significance of Serum NT-proBNP and Endogenous H₂S for Predicting Coronary Artery Lesions in Pediatric Kawasaki Disease.

Objective: To determine the expression levels and clinical significance of serum N-terminal pro-brain natriuretic peptide (NT-proBNP), hydrogen sulfide (H₂S) and interleukin-6 (IL-6) in children with Kawasaki disease (KD).

Study Design: Descriptive comparative study.

Place And Duration Of Study: Department of Pediatric Medicine, Baoding Children's Hospital, from July 2017 to July 2018.

[Changes in 25-hydroxyvitamin D3 level in children with Henoch-Schönlein purpura].

Objective: To examine the changes in 25-hydroxyvitamin D [25-(OH)D] level in children with Henoch-Schönlein purpura (HSP) and its clinical significance.

Methods: A total of 92 HSP children were included in this study, and were divided into HSP nephritis (HSPN) group (31 cases) and HSP group (61 cases) based on the presence or absence of HSPN. Alternatively, the patients were divided into purpura alone group (22 cases), purpura with joint symptoms group (joint symptom group, 24 cases), purpura with gastrointestinal symptoms group (gastrointestinal symptom group, 20 cases), and purpura with joint and gastrointestinal symptoms (mixed group, 26 cases) based on their clinical symptoms.

Effects of early enteral nutrition on the gastrointestinal motility and intestinal mucosal barrier of patients with burn-induced invasive fungal infection.

Objective: To evaluate the effects of early enteral nutrition on the gastrointestinal motility and intestinal mucosal barrier of patients with burn-induced invasive fungal infection.

Methods: A total of 120 patients with burn-induced invasive fungal infection were randomly divided into an early enteral nutrition (EN) group and a parenteral nutrition (PN) group (n=60). The patients were given nutritional support intervention for 14 days, and the expression levels of serum transferrin, albumin, total protein, endotoxin, D-lactic acid and inflammatory cytokines were detected on the 1st, 7th and 14th days respectively.

Finely engineered slow light photonic crystal waveguides for efficient wideband wavelength-independent higher-order temporal solitons.

By orthogonally dual-shifting the air-hole rows in the triangular photonic crystal waveguide, a novel finely engineered slow light silicon photonic crystal waveguide is designed for higher-order temporal solitons and ultrashort temporal pulse compression with a large fabrication tolerance. The engineering of dispersion provides the waveguide with a wide wavelength range with only low anomalous dispersion covering, which makes the compression ratio wavelength-independent and stable even under ultralow input pulse energy. The simulation results are based on nonlinear Schrödinger equation modeling, which demonstrates that the input picosecond pulses in the broad wavelength range with ultralow pJ pulse energy can be stably compressed by a factor of 6 to higher-order temporal solitons in a 250 μm short waveguide.

[Changes in 25-hydroxyvitamin D3 level and its significance in children with Kawasaki disease].

Objective: To investigate the changes in the serum level of 25-hydroxyvitamin D3 [25-(OH)D3] and its significance in children with Kawasaki disease (KD).

Methods: The clinical data of 242 KD children were collected. According to the presence or absence of coronary artery lesion (CAL), these children were classified into CAL group (63 children) and non-CAL (NCAL) group (179 children).

[Serum hydrogen sulfide levels in children with benign infantile convulsions associated with mild gastroenteritis].

Objective: To study the changes and significance of serum hydrogen sulfide (H2S) levels in children with benign infantile convulsions associated with mild gastroenteritis (BICE).

Methods: Forty-two hospitalized children diagnosed with BICE were recruited to the observation group, and 46 children admitted due to acute gastroenteritis alone were recruited to the control group. Serum H2S levels were measured by a spectrophotometer.

Cross-correlation frequency-resolved optical gating and dynamics of temporal solitons in silicon nanowire waveguides.

We demonstrate the evolution of picosecond pulses in silicon nanowire waveguides by sum frequency generation cross-correlation frequency-resolved optical gating (SFG-XFROG) and nonlinear Schrödinger equation (NLSE) modeling. Due to the unambiguous temporal direction and ultrahigh sensitivity of the SFG-XFROG, which enable observation of the pulse accelerations, the captured pulses' temporal and spectral characteristics showed remarkable agreement with NLSE predictions. The temporal intensity redistribution of the pulses through the silicon nanowire waveguide for various input pulse energies is analyzed experimentally and numerically to demonstrate the nonlinear contributions of self-phase modulation, two-photon absorption, and free carriers.