Publications by authors named "Yuan-zhen Qu"

Aims: This study aimed to investigate the associations among retinal vessel density (RVD), neuroimaging features and cognitive impairment in patients with sporadic cerebral small vessel disease (CSVD).

Methods: This was a prospective observational study. A total of forty-nine patients with CSVD were recruited.

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Article Synopsis
  • The study focuses on the relationship between retinal nerve fiber layer (RNFL) thickness, measured via optical coherence tomography (OCT), and clinical symptoms in Alzheimer's disease (AD) patients.
  • Out of 96 patients, 54.4% showed reduced RNFL thickness, which was significantly correlated with poorer performance in cognitive functions like memory, language, and attention.
  • Lower RNFL thickness also indicated a decline in activities of daily living, suggesting that RNFL thickness could serve as a potential indicator of cognitive decline in AD patients, warranting further research.
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Objectives: To analyze the differences and correlation between the ganglion cell complex (GCC), peripapillary retinal nerve fiber layer (pRNFL) and mean deviation (MD), mean sensitivity (MS) of saddle area tumor patients, and to evaluate the feasibility of using OCT to diagnose the visual pathway damage of saddle area tumor patients.

Methods: It was a case-control study. One hundred and eighty-eight normal persons and 279 saddle area tumor patients treated in Beijing Tiantan hospital, from November 2010 to June 2011, were recruited; the saddle area tumor patients were diagnosed by surgical sample pathological analysis.

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