17q21 locus rs7216389 polymorphism and childhood asthma risk: a meta-analysis.

Introduction: Recently, a genome-wide association study (GWAS) indicated that rs7216389 polymorphism on chromosome 17q21 was associated with paediatric asthma risk. However, the results remained controversial. Therefore, a meta-analysis was performed.

[Detection of Angiostrongylus cantonensis larvae with a high resolution melt PCR assay].

Objective: To develop a detection method of the third-stage larvae of Angiostrongylus cantonensis by real-time PCR and high-resolution melt curve analysis.

Methods: A pair of specific primers was designed based on the internal transcribed spacer 1 (ITS1) region of the nuclear ribosomal DNA of A. cantonensis.

[Autopsy study for maxillary nerve and its artery supply].

Objective: To observe the travel, divisions, and the lengths, diameters, branches, artery supplies of the main segments of maxillary nerve.

Methods: Fifty formalin-preserved adult half-head specimens with intravascular injection of red color emulsion were used for the gross and microanatomical studies of maxillary nerve. The lengths, diameters, branches and artery supplies of four main segments of maxillary nerve were observed.

[New compound NL-608 (a nutlin analog) induces apoptosis in human breast cancer MCF-7 cells].

Objective: To observe the effect of NL-608 (a nutlin analog) on apoptosis induction in human breast cancer MCF-7 cells in vitro, and investigate the relevant molecular mechanism.

Methods: The effect of NL-608 on proliferation of MCF-7 cells was determined by MTT assay. The apoptosis in MCF-7 cells was determined by flow cytometry with annexin V-FITC and PI.

[Application of separating brachial plexus block combined with preoperative analgesia by patient controlled intravenous analgesia in tendon repair].

Objective: To investigate whether the separating brachial plexus block combined with preoperative analgesia by patient controlled analgesia (PCA) can be applied in tendon repair and postoperative active or passive functional exercise.

Methods: Two hundred and ten cases with tendon injury were randomly divided into 3 groups and all of the patients were administered Bupivacaine (0.25%), Papaverine (0.