Publications by authors named "Yuan-qi Xiao"
[Epidemiological investigation on major depressive disorder in the most heavily damaged areas from Wenchuan earthquake in 2008].
Zhonghua Liu Xing Bing Xue Za Zhi
February 2010
Article Synopsis
- A study conducted in the aftermath of the 2008 Wenchuan earthquake aimed to understand the prevalence of major depressive disorder (MDD) among residents, finding a point prevalence of 1.27% and a lifetime prevalence of 1.36% among the 14,503 participants.
- Key risk factors for MDD included being female, suffering from other physical health issues, experiencing significant property loss, and the trauma of injury or loss of family members during the earthquake.
- Having a job emerged as a protective factor against developing MDD, highlighting the need for ongoing support and mental health care in disaster-affected communities.
Background & Aims: Molecular misreading of the ubiquitin B gene has been documented in the cerebral cortex of patients with Alzheimer's disease and Down syndrome. This novel process consists of the unfaithful conversion of genomic information into aberrant transcripts and its subsequent translation into +1 proteins.
Methods: Because Mallory bodies (MBs) also contain ubiquitinated proteins, we stained 11 autopsied and 6 biopsied MB-containing livers from patients with steatohepatitis with an antibody to ubiquitin(+1) to look for the presence of mutant (ubiquitin(+1)) protein.