Publications by authors named "Yuan-peng Huang"

Background: Benign prostatic hyperplasia (BPH) affects 30% of men worldwide, folate is essential for life. However, few studies have investigated the relationship between folate levels and BPH. The present study aims to explore the relationship between red blood cell (RBC) folate, a better indicator of long-term folate intake, and BPH in United States (US) men.

View Article and Find Full Text PDF

Background: Benign prostatic hyperplasia (BPH) is a common disease in older men worldwide. However, there is currently no effective treatment for BPH. Bushen Tongluo Formula (Kidney-supplementing and collaterals-unblocking formula [KCF]) is a traditional Chinese medicine formula commonly used to ameliorate the symptoms of BPH, although the specific molecular mechanisms remain unclear.

View Article and Find Full Text PDF

Objective: To investigate the effect of Kangquan Recipe (, KQR) on bone morphogenetic protein and activin membrane-bound inhibitor (BAMBI) expression and its mechanism in rats with benign prostatic hyperplasia (BPH).

Methods: Forty-eight male Sprague-Dawley rats were divided into 6 groups using a random number table, with 8 in each group: the normal group (normal saline 10 mL/kg), the model group (normal saline 10 mL/kg), the finasteride group (0.5 mg/kg), the low-dose KQR group (3.

View Article and Find Full Text PDF

Four new rearranged eudesmane sesquiterpenoids, Lyciiterpenoids A-D (), together with four known compounds () were isolated from the aqueous extract of Lycii Cortex. Their structures were elucidated by spectroscopic analysis, and the absolute configurations of compounds were determined by the quantum chemical ECD calculations. The absolute configuration of was further confirmed by X-ray crystallographic data analysis.

View Article and Find Full Text PDF

Acupuncture and moxibustion proved to be very effective in chronic atrophic gastritis (CAG). According to the Chinese traditional medicine theory, chronic diseases have an influence on the function of liver and kidney. However, there is little research to demonstrate this theory.

View Article and Find Full Text PDF

Three new lignanamides, that is, a new lignanamide (), and a pair of enantiomers ( and ) were isolated from the EtOAc-soluble fraction of an EtOH extract of the root of . The structures of these new compounds, including their absolute configuration, were established on the basis of HR-ESI-MS, NMR spectroscopic data and quantum chemical ECD calculations. Compound showed significant anti-inflammatory activity in LPS-induced RAW 264.

View Article and Find Full Text PDF

A new lignanamide (), lyciumamide K, together with four known analogues (-), was isolated from the root of Kuang. Based on HR-ESI-MS, NMR spectral data and quantum chemistry ECD calculations, the structure of this new compound was confirmed, including its absolute configuration. Evaluation of the antioxidant activity of compounds - in the oxygen radical absorption capacity (ORAC) assay showed that they all exhibited significant antioxidant activities.

View Article and Find Full Text PDF

Objective: To observe the effectiveness and safety of Kangquan Recipe (康泉方, KQR) for benign prostatic hyperplasia (BPH) patients.

Methods: One hundred and six BPH patients were randomly assigned to the treatment group (53 cases) and the control group (53 cases) according to a random number table. The treatment group was given KQR orally; the control group was given cernilton orally.

View Article and Find Full Text PDF

A cell rotation method by using optoelectronic tweezers (OET) is reported. The binary image of a typical OET device, whose light and dark sides act as two sets of parallel plates with different ac voltages, was used to create a rotating electric field. Its feasibility for application to electrorotation of cells was demonstrated by rotating Ramos and yeast cells in their pitch axes.

View Article and Find Full Text PDF

Objective: To investigate the effects of Kangquan Recipe (KQR) on sex steroids and cell proliferation in an experimental benign prostatic hyperplasia (BPH) model in rats.

Methods: Seventy-two SD rats were randomly divided into six groups: the normal group, the model group, the finasteride group, and the low-, middle-, and high-dose KQR groups, 12 in each group. Except those in the normal group, the rats were injected with testosterone after castration for the establishment of BPH model and then given respectively with normal saline, finasteride, and low-, middle-, and high-dose of KQR for 30 days.

View Article and Find Full Text PDF

Objective: To investigate the effect of Kangquan Recipe (KQR) on basic fibroblast growth factor (bFGF) in prostatic tissue of rats.

Methods: Benign prostatic hyperplasia model rat was established by injecting testosterone after castration. After being administered with KQR by gastrogavage for 30 days, the model rats were killed and their abdominal lobe prostate glands were taken for determining the protein and mRNA expressions of bFGF using immunohistochemical method and RT-polymerase chain reaction (RT-PCR) respectively.

View Article and Find Full Text PDF

Objective: To investigate the effect of Kangquan Recipe (KQR) on apoptosis regulatory genes bax and bcl-2 mRNA in prostate of rats.

Methods: Benign prostatic hyperplasia model rat was established by injecting testosterone after castration. The model rats were killed and prostate glands were removed for examination after being treated with administration of KQR by gastrogavage for 30 days.

View Article and Find Full Text PDF