Publications by Yuan-jun Ruan

Publications by authors named "Yuan-jun Ruan"

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[Protective effects of estrogen on mitochondria in human umbilical vascular endothelial cells].

Guo-dong Chen Sai-zhu Wu Yuan-jun Ruan Hui-ru Peng Xiao-wen Xing

Nan Fang Yi Ke Da Xue Xue Bao

July 2008

Objective: To investigate the protective effects of estrogen on the mitochondria in human umbilical vascular endothelial cells (HUVECs).

Methods: HUVECs were exposed to H2O2 at 250 micromol/L for 4 h with or without pretreatment with 17-estradiol (E2) and ICI182780. Complex IV activity of the cells was measured with chromometry, and 2, 7-dichlorofluorescein diacetate (DCFH-DA) was used to determine intracellular reactive oxygen species (ROS).

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