Blood coagulation dynamic testing sensor based on electromagnetic vibration.

Rapid detection techniques and methods of blood coagulation have attracted wide attention in academia and the business community in the presence of the increased demands for rapid assessment (point-of-care testing) of patients from surgery, intensive care unit, and other departments. The differential equation of vibration system composed of elastic support and electromagnetic induction devices was set up using the principle of damping vibration and establishing the dynamics model; meanwhile, the harmonic response analysis and vibration fatigue coupling analysis were carried out, the analysis results were optimized, and the experimental device of the electromagnetic induction testing sensor was established. In addition, the experimental device with blood coagulation reagent was assorted to establish the standard point-of-care testing rapid blood coagulation detection curve, and to compare the testing curve with that of the imported point-of-care testing blood coagulation instrument.

Phosphorescent quantum dots/ethidium bromide nanohybrids based on photoinduced electron transfer for DNA detection.

Mercaptopropionic acid-capped Mn-doped ZnS quantum dots/ethidium bromide (EB) nanohybrids were constructed for photoinduced electron transfer (PIET) and then used as a room-temperature phosphorescence (RTP) probe for DNA detection. EB could quench the RTP of Mn-doped ZnS QDs by PIET, thereby forming Mn-doped ZnS QDs/EB nanohybrids and storing RTP. Meanwhile, EB could be inserted into DNA and EB could be competitively desorbed from the surface of Mn-doped ZnS QDs by DNA, thereby releasing the RTP of Mn-doped ZnS QDs.

Toxicity of sodium fluoride to Caenorhabditis elegans.

Objective: To investigate the toxic effect of sodium fluoride (NaF) on the nematode Caenorhabditis elegans (C. elegans).

Methods: Adult C.