Publications by authors named "Yuan-hong Shi"

Background: Major depression disorder (MDD) exhibits a high global incidence; however, its pathogenesis remains elusive. In this prospective study, we employed diffusion kurtosis imaging (DKI) to investigate changes in brain function among patients with MDD both pre- and post-electroconvulsive therapy (ECT).

Methods: We divided a sample of 22 MDD patients into ECT group, which received six treatments over a span of two weeks, and control group (n = 12).

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Background: Acupuncture, a key component of traditional Chinese medicine, is a form of alternative medicine in which thin needles are inserted into the body commonly for pain relief. To date, the role of traditional Chinese acupuncture in mood disorders in the postpartum period is unclear. Thus, this study aimed to review the effectiveness of acupuncture in patients with postpartum depression (PPD).

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Article Synopsis
  • The study aimed to evaluate how effective modified aspiration techniques are compared to traditional ones in treating patients with spontaneous intracerebral hemorrhage (ICH).
  • 159 patients were analyzed, with 66 receiving traditional aspiration and 93 receiving modified aspiration, both paired with thrombolysis; the results showed lower mortality and re-bleeding rates in the modified group.
  • Patients in the modified aspiration group also had better long-term outcomes, as evidenced by significantly higher Barthel Index scores compared to those in the traditional group.
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Objective: To investigate the clinical efficacy of clot aspiration in the treatment of intracerebral hemorrhage (ICH) by reviewing literatures.

Methods: All studies assigned into two groups of hard or soft tunnel aspiration of clots (HTAC or STAC) on the basis of surgical approaches were obtained by searching four major Chinese medical databases. And the surgical outcomes were descriptively analyzed.

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Background: Stroke and traumatic injury to the nerve system may trigger axonal destruction and the formation of scar tissue, cystic cavitations and physical gaps. Olfactory ensheathing cells (OECs) can secrete neurotrophic factors to promote neurite growth and thus act as a prime candidate for autologous transplantation. Biological scaffolds can provide a robust delivery vehicle to injured nerve tissue for neural cell transplantation strategies, owing to the porous three-dimensional structures (3D).

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Objective: To investigate the effects of combined transplantation of neural stem cells (NSC) and olfactory ensheathing cells (OEC) on the motor function of rats with intracerebral hemorrhage.

Methods: In three days after a rat model of caudate nucleus hemorrhage was established, NSCs and OEC, NSC, OEC (from embryos of Wistar rats) or normal saline were injected into hematomas of rats in combined transplantation group, NSC group, OEC group, and control group, respectively. Damage of neural function was scored before and in 3, 7, 14, 30 days after operation.

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Article Synopsis
  • The study developed a model of supratentorial intracerebral hemorrhage (ICH) in piglets to mimic neurological deficits commonly observed in humans.
  • During the experiment, 18 piglets received blood injections after balloon inflation in the brain, with 16 developing a significant hematoma and displaying behavioral deficits like lameness within 24 hours.
  • This model successfully induced brain tissue damage that worsened initially but showed signs of improvement after a week, making it a useful tool for researching ICH treatments and effects.
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