Synopsis of recent research by authors named "Yuan-Zhao Lin"
- Yuan-Zhao Lin's research primarily focuses on the genetic and epigenetic factors associated with autoimmune diseases such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), examining gene polymorphisms, methylation patterns, and immune responses in affected patients.
- Recent studies have highlighted significant associations between specific gene polymorphisms (e.g., NLRP3, CD209, and OSMR) and the susceptibility or severity of autoimmune conditions, demonstrating the role of these genetic variations in disease progression.
- Lin's investigations into the methylome and transcriptome of peripheral blood mononuclear cells have revealed distinct methylation signatures and alterations in gene expression that may contribute to the pathogenesis of RA and SLE, indicating potential biomarkers and therapeutic targets.