Publications by authors named "Yuan-Sheng Fang"
Background: Lung adenocarcinoma (LUAD) is the most popular type of lung cancer. Sulfotanshinone IIA sodium (STS IIA) has been proven to have an anticancer effect. However, its role in LUAD and its underlying mechanism remain unclear.
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- Sodium tanshinone IIA sulphate (STS) shows potential anti-tumor effects against lung adenocarcinoma (LUAD) by significantly reducing cell viability, migration, invasion, and angiogenesis.
- The study found that STS's effectiveness is partly mediated by miR-874, which targets eEF-2K; downregulation of miR-874 diminishes STS's antitumor impact.
- Overall, the findings suggest that STS could be a promising treatment for lung cancer, especially when combined with traditional chemotherapy, by targeting specific molecular pathways.
Non-invasive and label-free spectral microscopy (spectromicroscopy) techniques can provide quantitative biochemical information complementary to genomic sequencing, transcriptomic profiling, and proteomic analyses. However, spectromicroscopy techniques generate high-dimensional data; acquisition of a single spectral image can range from tens of minutes to hours, depending on the desired spatial resolution and the image size. This substantially limits the timescales of observable transient biological processes.
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