Change in late sodium current of atrial myocytes in spontaneously hypertensive rats with allocryptopine treatment.

Aim: We aimed to study the effect of allocryptopine (All) on the late sodium current (I) of atrial myocytes in spontaneously hypertensive rats (SHR).

Methods: The enzyme digestion method was used to separate single atrial myocytes from SHR and Wistar-Kyoto (WKY) rats. I was recorded using the patch-clamp technique, and the effect of All was evaluated on the current.