Introduction: This study observed the effectiveness of ustekinumab and reactivation risk of concurrent latent tuberculosis infection (LTBI) and inactive hepatitis B virus (HBV) infection in Chinese mainland psoriasis patients on ustekinumab treatment.
Methods: This retrospective, multicenter, observational study was conducted in three centers in China. Adult patients with moderate to severe plaque psoriasis were treated with ustekinumab for 28 weeks.
MiRNAs were involved in the various biological process through mediating the posttranscriptional gene silencing. The abnormal expression of miRNAs is also involved in various disorders. Our previous study showed that miRNA-27a (miR-27a) was upregulated after ultraviolet B (UVB) irradiation.
View Article and Find Full Text PDFBy collecting water and sediment samples from Yangzonghai Lake and analyzing the total amount and speciation of arsenic, the spatial distribution of arsenic in surface water and sediments was analyzed, the current status of arsenic pollution were estimated, the anthropogenic contribution rate and the arsenic reserve in the lake were calculated respectively. Meanwhile, the sources of arsenic were investigated. The results indicated that the total arsenic content in Yangzonghai Lake was 71.
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