Publications by authors named "Yuan-Jie Hao"
Acute myocardial infarction (AMI) is a leading cause of heart failure, often accompanied by myocardial fibrosis (MF), characterized by excessive extracellular matrix accumulation. Endothelial-to-mesenchymal transition (EndMT) plays a key role in MF progression post-AMI. Neuregulin-1 (NRG-1), a growth factor with cardioprotective properties, has emerged as a potential therapeutic target.
View Article and Find Full Text PDFEarly detection of multiple endocrine neoplasia type 1: A case report.
World J Gastroenterol
July 2024
Article Synopsis
- * A case study highlighted a middle-aged male who experienced recurrent abdominal pain and diarrhea, leading to the early detection of MEN1 through blood tests that indicated hypercalcemia and hypophosphatemia, as well as imaging studies.
- * The diagnosis was confirmed through surgery, showing a parathyroid adenoma and a neuroendocrine tumor, emphasizing the need for clinicians to consider MEN1 in patients with gastrointestinal symptoms and abnormal calcium levels.*
Objective: To investigate the potential role of Tongxinluo (TXL) in attenuating myocardial fibrosis after myocardial ischemia-reperfusion injury (MIRI) in mice.
Methods: A MIRI mouse model was established by left anterior descending coronary artery ligation for 45 min. According to a random number table, 66 mice were randomly divided into 6 groups (n=11 per group): the sham group, the model group, the LY-294002 group, the TXL group, the TXL+LY-294002 group and the benazepril (BNPL) group.
Impaired intestinal barrier function in type 2 diabetic patients measured by serum LPS, Zonulin, and IFABP.
J Diabetes Complications
February 2021
Introduction: The epithelial tight junctions of intestine were impaired in murine model of type 2 diabetes mellitus (T2DM). The aim of this work was to investigate the alteration of intestinal barrier in T2DM patients.
Methods: 90 patients with T2DM and 28 healthy controls were recruited.