[Quantitative Assessment of Skin Thickness using High Frequency Ultrasound in Systemic Sclerosis].

Objective: To investigate the performance of high frequency ultrasound in the assessment of skin thickness in patients with systemic sclerosis (SSc).

Methods: The study included 82 SSc (SSc group) and 67 healthy volunteers (control group) from 2014 to 2016. The skin thickness at bilateral middle fingers and forearms,anterior chest and abdominal wall was measured using high frequency ultrasound.

[Ultrasonic Features of Enthesitis: a Comparison Between Patients with Psoriasis Vulgaris and Patients with Psoriatic Arthritis].

Objective: To compare the ultrasonic features of enthesitis between psoriatic arthritis and psoriasis vulgaris.

Methods: A total of 39 patients with psoriatic arthritis (PsA group), 60 with psoriasis vulgaris (non-PsA group) and 60 healthy people (control group) participated in this study. They were examined by two-dimensional and color Doppler ultrasound on the entheses of bilateral femoral quadriceps tendons, patella tendons, Achilles tendons, plantar fasciae, common flexor tendons and common extensor tendons.

[The Value of High Frequency Color Doppler Ultrasonography in the Diagnosis of Solid Skin Tumorsa-a Preliminary Study].

Objectives: To explore the value of high frequency color doppler ultrasonography in differentiating benign and malignant skin solid tumors.

Methods: Clinical and ultrasonic data of cutaneous solid tumors confirmed by pathology in our hospital were collected. The differences in clinical and sonographic features between benign and malignant tumors were statistically analyzed.

[Correlation between quantitative results of contrast-enhanced ultrasonography and clinical and laboratory indexes for synovium of patients with rheumatoid arthritis ].

Objective: To determine the correlation between quantitative results of contrast enhanced ultrasound and clinical and laboratory index for synovium of patients with rheumatoid arthritis (RA).

Methods: Thirty five RA patients participated in this study, with ten normal adults serving as controls. They were given a score of DAS28 and underwent laboratory tests, including erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP).

[Enhanced local gene transfection in rats with injured achilles tendons and granulation tissues using ultrasound and microbubble].

Objective: To identify best local ukrasound transfection conditions in rats with injured achilles tendons and granulation tissues.

Methods: Rat models with bilateral injured achilles tendons were established. A mixture of microbubbles and enhanced green fluorescent protein (EGFP) plasmids were injected into the achilles tendons.

[Diagnostic value of ultrasound imaging in chronic gouty arthritis].

Objective: To determine the diagnostic value of ultrasound imaging in chronic gouty arthritis.

Methods: Ultrasound imaging of 32 patients with chronic gouty arthritis were compared with those of 36 patients with non-gouty joint diseases. A logistic model was obtained to establish the associations between ultrasound appereances and gouty arthritis.

[Study on the parameter optimization for therapeutic ultrasound mediated microbubble destruction enhancs gene transfection in rat muscle in vivo].

Objective: To search for the most suitable gene transfection conditions for rat muscle in vivo by therapertic ultrasound-mediated microbubble destruction (UMMD).

Methods: A mixture of microbubbles and enhanced green flurescence protein (EGFP) plasmids was injected into rat tibialis anterior muscle and the muscels treated with ultrasound irradiation by different output intensity, duty cycle and irradiation time of therapeutic ultrasound. The transfection efficiency was demonstrated by the EGFP expression results under fluorescent staining and immunohistochemical staining.