Publications by authors named "Yuan-Bo Liang"
Aim: Normal tension glaucoma (NTG) is a common optic neuropathy that can be challenging to diagnose due to the intraocular pressure remaining within the normal range. Early diagnosis and intervention are crucial for the effective lifelong management of patients.
Methods: This study recruited a total of 225 participants.
Aim: To report a one-year clinical outcomes of low-dose laser cycloplasty (LCP) among malignant glaucoma patients.
Methods: In this prospective, multicenter, non-comparative clinical study, participants with malignant glaucoma were recruited and underwent LCP at eight ophthalmic centers in China. Patients were followed up at 1wk, 1, 3, 6, and 12mo.
Glaucoma is a leading cause of irreversible blindness worldwide and is characterized by progressive retinal ganglion cell (RGC) degeneration and vision loss. Since irreversible neurodegeneration occurs before diagnosable, early diagnosis and effective neuroprotection are critical for glaucoma management. Small extracellular vesicles (sEVs) are demonstrated to be potential novel biomarkers and therapeutics for a variety of diseases.
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- * Among the 300 eyes studied, short eyes had the smallest CACD and white-to-white distance (WTW), while lens thickness (LT) was significantly thicker in short eyes compared to normal and long eyes.
- * The findings suggest that CACD increases with longer axial lengths and is influenced by lens thickness and WTW, with a smaller WTW indicating a more forward-positioned lens and a reduction in CACD.
Article Synopsis
- - The study aimed to evaluate the effectiveness of low-dose laser cycloplasty (LCP) in treating chronic angle-closure glaucoma (CACG), focusing on outcomes like intraocular pressure (IOP) and medication use.
- - Data from 7 CACG patients who underwent LCP revealed significant reductions in mean IOP (from 26.1 to 14.9 mm Hg) and the number of glaucoma medications (from 3.1 to 0.4) over an average follow-up of 27 months.
- - Results indicated improvement in anterior segment parameters, with most patients showing deepening of anterior chamber depth and reopening of the anterior chamber angle, suggesting LCP is a promising and safe treatment for CACG
Significance: This study reported the relationship between intraocular pressure (IOP) and myopia progression, which helps to understand more comprehensively whether IOP can be an important reference factor to intervene in the progression of myopia.
Purpose: This study aimed to investigate the association between IOP and myopia progression as well as axial length elongation in rural Chinese children.
Methods: A total of 598 (598 of 878 [68.
Purpose: To investigate the association between mean ocular perfusion pressure (MOPP), estimated cerebrospinal fluid pressure (CSFP), and changes in diabetic retinopathy (DR) in a Northeastern Chinese population with Type 2 diabetes.
Methods: A total of 1,322 subjects from the Fushun Diabetic Retinopathy Cohort Study were enrolled. Systolic blood pressure (SBP), diastolic blood pressure (DBP), and intraocular pressure (IOP) were recorded.
Aim: To evaluate the trend of glaucoma internal filtration surgeries for inpatients between 2015 and 2021 at the Eye Hospital of Wenzhou Medical University.
Methods: A review of the medical records of inpatients who had been diagnosed with glaucoma and received anti-glaucoma surgery between January 1, 2015 and December 31, 2021 was conducted. The glaucoma diagnosis in this study included primary open angle glaucoma, primary angle-closure glaucoma, secondary glaucoma, and paediatric glaucoma.
Aim: To report the outcomes of penetrating canaloplasty for corticosteroid-induced glaucoma in a case series.
Methods: Penetrating canaloplasty is a bleb-independent filtering surgery unifying canaloplasty and trabeculectomy. In this study, the surgery was performed to restore the natural outflow through surgically expanded Schlemm's canal and generated trabeculum ostium.
Objective: This study aimed to assess the knowledge, attitude, and practice (KAP) of diabetic subjects with diabetic retinopathy (DR) and those without DR (NDR) in an urban community in Northeast China, as well as their risk factors in subjects with DR and NDR.
Methods: A community-based survey involving 1,662 subjects was conducted in Fushun, China, between July 2012 and May 2013. The subjects included diabetics with DR ( = 783) and those NDR ( = 879), and questionnaires were completed to collect information about their sociodemographic and healthcare characteristics.
Purpose: To describe the prevalence and risk factors for refractive errors in a northeastern Chinese population with type 2 diabetes.
Methods: Subjects (age ≥30 years) from a community-based study, the Fushun Diabetic Retinopathy Cohort Study, were enrolled. All subjects underwent comprehensive ocular examinations, including autorefraction.
Aim: To estimate the prevalence of diabetic macular edema (DME) and clinically significant macular edema (CSME), and to assess their risk factors in a population with type 2 diabetic mellitus (T2DM) located in northeast China.
Methods: Patients were included from the Fushun Diabetic Retinopathy Cohort Study (FS-DIRECT), a community-based study conducted in northeast China. The presence of DME and CSME was determined by the Early Treatment Diabetic Retinopathy Study (ETDRS) retinopathy scale of fundus photographs.
Aim: To investigate fluctuation of intraocular pressure (IOP) and seasonal variation of 24-hour IOP during one year in healthy participants.
Methods: Totally 13 young healthy volunteers participated in this study. IOP was measured with Canon TX-20 at about 8:00-9:00 .
Aim: To investigate the association of peripheral anterior synechiae (PAS) with intraocular pressure (IOP) and glaucomatous optic neuropathy (GON) in primary angle closure (PAC) and primary angle-closure glaucoma (PACG).
Methods: Totally 355 eyes (238 PAC and 117 PACG) of 181 patients were included in this retrospective analysis of baseline data from a randomized clinical trial. All patients had undergone a comprehensive ophthalmic examination.
Purpose: To investigate the association between metabolic syndrome (MetS) and diabetic retinopathy (DR), as well as the association between MetS and retinal vessel caliber, among Chinese patients with type 2 diabetes mellitus in north-eastern China.
Study Design: Cross-sectional study.
Patients And Methods: The patients were recruited from a community-based study, the Fushun Diabetic Retinopathy Cohort Study (FS-DIRECT).
Purpose: To assess the distribution and factors related to intraocular pressure (IOP) in a Chinese children population in Northern China.
Methods: 1,238 offspring aged 6 to 18 years, residing in six villages, were recruited for this current study, the Handan Offspring Myopia Study. Participants underwent an interviewer-administered questionnaire and a complete ocular examination, including standardized measurement of IOP with Perkins applanation tonometry.
Aim: To report the progression rate (PR) to primary angle closure (PAC) following laser peripheral iridotomy (LPI) in PAC suspects (PACS).
Methods: Prospective, randomized controlled interventional clinical trial conducted at the Handan Eye Hospital, China. Totally 134 bilateral PACS, defined as non-visibility of the posterior trabecular meshwork for ≥180 degrees on gonioscopy were randomly assigned to undergo LPI in one eye.
Purpose: To examine the association between near work, screen time including TV and outdoor time with myopia in children from the Sunflower Myopia Asian Eye Epidemiology Consortium (AEEC).
Methods: We analysed AEEC cross-sectional data (12 241 children) on risk factors (near work, screen time including TV and outdoor time) and myopia of six population-based studies (China, Hong Kong and Singapore). Cycloplegic refraction and axial length (AL) measurements were included.
Purpose: To evaluate the prevalence and causes of visual impairment in a group of community people with type 2 diabetes mellitus (T2DM) in Northeast China.
Methods: Population-based cross-sectional survey. Patients diagnosed with T2DM residing in 15 communities in Fushun, Northeast China, were enrolled between July 2012 and May 2013.
Purpose: To investigate the impact of eye exercises of acupoints on myopic progression among Chinese urban students.
Methods: The Beijing Myopia Progression Study (BMPS) was a three-year cohort study, with 386 students (aged 6-17 years) enrolled at baseline. These students were invited to be reexamined in the years 2011, 2012, and 2013.
Objective: To evaluate the association between diabetic retinopathy (DR) and mean ocular perfusion pressure (MOPP) in patients with type 2 diabetes mellitus (T2DM).
Methods: Patients from the Fushun Diabetic Retinopathy Cohort Study (FS-DIRECT), a community-based prospective cohort study conducted in northeast China, were included in this study. The presence and severity of DR were determined by grading fundus photographs according to the Early Treatment Diabetic Retinopathy Study (ETDRS) retinopathy scale.
Objectives: This study aimed to assess the association between the corneal biomechanical parameters and visual field (VF) loss in patients with asymmetric primary open-angle glaucoma (POAG).
Methods: A total of 89 POAG patients (50 males, 56.2%) with asymmetric VF loss, aged 65.
Purpose: To investigate the natural change of nearwork-induced transient myopia (NITM), and its association with the progression of refractive error.
Methods: Students of the Beijing Myopia Progression Study were examined at baseline and follow-up examinations, which included cycloplegic autorefraction. Initial NITM and its decay were assessed objectively immediately after binocularly-viewing and performing a sustained 5-minute near task (20 cm).
Purpose: To investigate the association between high myopia and diabetic retinopathy, and its possible mechanism, in a northeastern Chinese population with type 2 diabetic mellitus.
Methods: Patients were included from Fushun Diabetic Retinopathy Cohort Study. High myopia was defined as spherical equivalent of autorefraction less than -5D.
Article Synopsis
- - The study aimed to assess the eye-care knowledge, attitudes, and practices of visually impaired adults in rural Yueqing, identifying factors that influence their behavior toward seeking medical eye care.
- - Out of 2400 people screened, 165 had moderate-to-severe visual impairment, with only 15% receiving regular vision checks; common barriers to care included feeling it was unnecessary and having scheduling conflicts.
- - The findings suggest that increased education about eye care, particularly for older adults and those with less education, is essential, and regular vision checks could improve the likelihood of seeking eye care services.