Synchrotron radiation (SR) diffraction enhanced imaging (DEI) of chronic glomerulonephritis (CGN) mode.

Objective: The aim of this study is to investigate microstructural changes in chronic glomerulonephritis (CGN) rabbit model under diffraction enhanced imaging (DEI) technology of synchrotron radiation (SR).

Materials And Methods: The chronic glomerulonephritis (CGN) models were obtained within two months after 5 New Zealand white rabbits were treated with doxorubicin hydrochloride. Blood exams, urine tests and kidney histological studies were carried out after the 5 rabbits were humanely sacrificed by hyperanesthesia.

Visualising liver fibrosis by phase-contrast X-ray imaging in common bile duct ligated mice.

Objectives: To determine whether phase-contrast X-ray imaging can be used to visualise directly the accumulated extracellular matrix proteins associated with liver fibrosis in common bile duct ligated mice.

Methods: Twenty-six-week-old C57BL female mice were randomised into three groups. In groups 1 (n = 5) and 2 (n = 10), common bile duct ligation was conducted to produce secondary biliary cirrhosis.

Diffraction-enhanced radiography of various mouse organs.

Objective: The purposes of this study were to evaluate whether a novel radiographic technique, diffraction-enhanced radiographic imaging, would render high-contrast images of mouse livers, hearts, and kidneys and to determine whether blood vessels and bile ducts can be differentiated on images of mouse livers.

Materials And Methods: For imaging of the bile ducts, mouse livers were excised 20 or 35 days after ligation of the common bile duct. Livers, hearts, and kidneys of control mice also were excised for imaging.

Mouse blood vessel imaging by in-line x-ray phase-contrast imaging.

It is virtually impossible to observe blood vessels by conventional x-ray imaging techniques without using contrast agents. In addition, such x-ray systems are typically incapable of detecting vessels with diameters less than 200 microm. Here we show that vessels as small as 30 microm could be detected using in-line phase-contrast x-ray imaging without the use of contrast agents.

Strategy of extraction methods and reconstruction algorithms in computed tomography of diffraction enhanced imaging.

Computed tomography of diffraction enhanced imaging (DEI-CT) is a novel x-ray phase-contrast computed tomography which is applied to inspect weakly absorbing low-Z samples. Refraction-angle images which are extracted from a series of raw DEI images measured in different positions of the rocking curve of the analyser can be regarded as projections of DEI-CT. Based on them, the distribution of refractive index decrement in the sample can be reconstructed according to the principles of CT.