A randomized, multicenter and noninferiority study of amoxicillin plus berberine vs tetracycline plus furazolidone in quadruple therapy for Helicobacter pylori rescue treatment.

Objective: Helicobacter pylori (H. pylori) infection is closely associated with gastric ulcers and gastric adenocarcinomas. We aimed to assess the efficacy and safety of a quadruple regimen with amoxicillin plus berberine vs tetracycline plus furazolidone in rescue therapy for H.

Overexpression of NAD(P)H: Quinone Oxidoreductase 1 Inhibits Hepatocellular Carcinoma Cell Proliferation and Induced Apoptosis by Activating AMPK/PGC-1α Pathway.

Hepatocellular carcinoma (HCC) is the most common lethal malignancy and a leading cause of malignancy-associated death in many countries, but mainly in Asia. Expression of the NAD(P)H:quinone oxidoreductase 1 (NQO1) protein is involved in the growth of various human cancers, including HCC. NQO1 is considered an inhibitor of cancers.

[Relationship between cyclooxysenase 2 and serious hepatitis].

Aim: To study the cytokines regulated downstream effecter cyclooxygenase (COX-2's) function in the progression of serious hepatitis.

Methods: Samples from 75 patients with hepatitis B virus (HBV)-associated serious liver disease with well-characterised clincal profiles and 30 HBV-infected patients were assessed by ELISA.

Results: Compared with the general HBV-infected patients, serum TXB2 and 6-keto-PG1α level were uniformly elevated in all serious hepatitis patients (acute serious hepatitis patients vs general HBV-infected patients (P < 0.

[Expression and significance of glypican-3 in colorectal cancer].

Objective: To investigate the expression and significance of Glypican-3 in colorectal cancer.

Methods: Immunohistochemistry was used to detect the expression of Glypican-3 in 200 specimens of colorectal cancer and adjacent non-cancerous tissues resected during operation.

Results: Glypican-3 immunoreactivity was recognized in both the cytoplasm and cellular membrane.