Predicting Clinically Significant Prostate Cancer Using Urine Metabolomics via Liquid Chromatography Mass Spectrometry.

Purpose: Biomarkers predicting clinically significant prostate cancer (sPC) before biopsy are currently lacking. This study aimed to develop a non-invasive urine test to predict sPC in at-risk men using urinary metabolomic profiles.

Materials And Methods: Urine samples from 934 at-risk subjects and 268 treatment-naïve PC patients were subjected to liquid chromatography/mass spectrophotometry (LC-MS)-based metabolomics profiling using both C18 and hydrophilic interaction liquid chromatography (HILIC) column analyses.

Prediction of clinically significant prostate cancer through urine metabolomic signatures: A large-scale validated study.

Purpose: Currently, there are no accurate markers for predicting potentially lethal prostate cancer (PC) before biopsy. This study aimed to develop urine tests to predict clinically significant PC (sPC) in men at risk.

Methods: Urine samples from 928 men, namely, 660 PC patients and 268 benign subjects, were analyzed by gas chromatography/quadrupole time-of-flight mass spectrophotometry (GC/Q-TOF MS) metabolomic profiling to construct four predictive models.

Removal of gaseous polycyclic aromatic hydrocarbons from cooking fumes using an atmospheric plasma reactor.

Plasma technology is becoming increasingly important for treating various environmental pollutants. Treatment of polycyclic aromatic hydrocarbons (PAHs), such as those emitted from electric ovens while roasting pork, using an atmospheric plasma reactor has seldom been studied. This study investigated the characteristics of five PAH species (acenaphthalene (AcPy), acenaphthene (Acp), anthracene (Ant), benzo[a]anthracene (BaA), and benzo(ghi)perylene (BghiP)) in fumes emitted while roasting pork.

Sound characteristics of big-snout croaker, Johnius macrorhynus (Sciaenidae).

The sounds of a big-snout croaker, Johnius macrorhynus, produced under hand-held and voluntary conditions (in a large aquarium and in the field) were compared. Voluntary calls included "purr" and "dual-knocks", only purrs were produced when the fish was hand-held. The purr is composed of pulses in which the first interpulse interval was six to nine times longer than the other interpulse intervals, which were approximate in duration, and is a unique sound type in the coastal water of Taiwan.