Prevalence and distribution of ultrasound-detected hand synovial abnormalities in a middle-aged and older population.

Objective: Synovial abnormalities are modifiable targets for hand pain and osteoarthritis. We examined the prevalence and distribution of ultrasound-detected hand synovial abnormalities in a community-derived sample of older people in China.

Methods: Within the Xiangya Osteoarthritis Study, a community-based study, we assessed synovial hypertrophy (SH), joint effusion, and Power Doppler signal (PDS) on all fingers and thumbs of both hands using standardized ultrasound examinations (score: 0-3).

Early postsurgical lethal outcome due to splenic littoral cell angioma: A case report.

Background: Littoral cell angioma (LCA) is a rare benign vascular tumor of the spleen. Given its rarity, standard diagnostic and therapeutic recommendations have yet to be developed for reported cases. Splenectomy is the only method of obtaining a pathological diagnosis and providing treatment to obtain a favorable prognosis.

Ferric Chloride Controls Citrus Anthracnose by Inducing the Autophagy Activity of .

causes citrus anthracnose, which seriously endangers the pre-harvest production and post-harvest storage of citrus due to its devastating effects on fruit quality, shelf life, and profits. However, although some chemical agents have been proven to effectively control this plant disease, little to no efforts have been made to identify effective and safe anti-anthracnose alternatives. Therefore, this study assessed and verified the inhibitory effect of ferric chloride (FeCl) against .

Stage-Specific Transcriptomes of the Mussel Reveals the Developmental Program for the Planktonic to Benthic Transition.

Many marine invertebrate larvae undergo complex morphological and physiological changes during the planktonic-benthic transition (a.k.a.

Self-recovery of chiral microphase separation in an achiral diblock copolymer system.

Macroscopic regulation of chiral supramolecular nanostructures in liquid-crystalline block copolymers is of great significance in photonics and nanotechnology. Although fabricating helical phase structures chiral doping and microphase separation has been widely reported, the chiral memory and self-recovery capacity of asymmetric phase structures are the major challenge and still deeply rely on the presence of chiral additives. Herein, we demonstrate the first controllable chiral microphase separation in an achiral amphiphilic block copolymer consisting of poly(ethylene oxide) and azobenzene (Azo) groups.

Epidemiological and clinical characteristics of human rhinovirus caused bronchiolitis in children in Southeast China.

Background: Human rhinovirus (hRV) is a critical viral pathogen implicated in bronchiolitis in children. However, there is no study on hRV bronchiolitis in children from Southeast China. The aim of this study was to determine the incidence and clinical features of hRV bronchiolitis in Southeast China.

Molecular responses to salinity stress in (Koidz) females and males.

Sexual dimorphism has commonly been found in many species. The phenotypes of females and males are different under salinity stress. An F population was selected to compare the differences between males and females.

Promoting Angiogenesis Using Immune Cells for Tissue-Engineered Vascular Grafts.

Implantable tissue-engineered vascular grafts (TEVGs) usually trigger the host reaction which is inextricably linked with the immune system, including blood-material interaction, protein absorption, inflammation, foreign body reaction, and so on. With remarkable progress, the immune response is no longer considered to be entirely harmful to TEVGs, but its therapeutic and impaired effects on angiogenesis and tissue regeneration are parallel. Although the implicated immune mechanisms remain elusive, it is certainly worthwhile to gain detailed knowledge about the function of the individual immune components during angiogenesis and vascular remodeling.

Effectiveness of Virtual Reality in Symptom Management of Cancer Patients: A Systematic Review and Meta-Analysis.

Context: Although the survival rate of cancer patients has been increasing, such patients often experience severe physical and psychological burdens due to the effects of the disease and therapy. Multiple virtual reality (VR)-based interventions have been used to help improve physical and psychological symptoms and quality of life in cancer patients.

Objective: This study aimed to assess the effects of VR-based interventions on anxiety, pain, depression, fear, distress, and quality of life in cancer patients.

Paraben exposure and couple fecundity: a preconception cohort study.

Study Question: Is pre-conception exposure to parabens associated with fecundity in couples of childbearing age?

Summary Answer: Paraben exposure in female partners was associated with reduced couple fecundity and anti-Müllerian hormone (AMH) might be one of the possible mediators.

What Is Known Already: The reproductive toxicity of parabens, a class of widely used preservatives, has been suggested but evidence regarding their effects on couple fecundity is scarce.

Study Design, Size, Duration: In this couple-based prospective cohort study, a total of 884 pre-conception couples who participated in the Shanghai Birth Cohort between 2013 and 2015 were included.

Association between maternal polycystic ovary syndrome and attention-deficit/hyperactivity disorder in offspring aged 3-6 years: A Chinese population-based study.

Background: Maternal polycystic ovary syndrome (PCOS) may increase the risk of attention-deficit/hyperactivity disorder (ADHD) in offspring; however, their association remains unexplored in Asian populations. Hence, this study aimed to investigate the association between maternal PCOS and ADHD in offspring aged 3-6 years and whether it differed by offspring sex.

Methods: This was a district-wide population-based study of 87,081 preschoolers from 234 kindergartens in Longhua District, Shenzhen, China.

Robust Carbon Nitride Homojunction Photoelectrode for Solar-Driven Water Splitting.

Achieving intimate particle-to-particle and particle-to-substrate contacts is the first priority for fabricating high-quality photoelectrodes to ensure sufficient visible light absorption and efficient charge separation/transport. To achieve this goal, a seeding strategy is designed to construct a robust carbon nitride (CN) homojunction photoelectrode, in which vaporized precursors are condensed into a compact seeding layer at low temperatures, inducing the further deposition of the top layer. This optimized photoelectrode displays an excellent photocurrent density of 320 μA cm in 0.

Dysbiosis of gut microbiota, a potential mediator of bile acid compositions, and prevalence of hand synovitis: a community-based study.

Objectives: Hand synovitis, a potentially modifiable pathological lesion, is common and associated with pain and hand OA; nevertheless, its pathogenesis remains uncertain. This study investigated the relationship between gut microbiota dysbiosis and hand synovitis prevalence and evaluated whether bile acids mediate the association.

Methods: Participants were derived from a community-based observational study.

Study on spatio-temporal variation and hydrological connectivity of tidal creek evolution in Yancheng coastal wetlands.

The ecological changes have attracted extensive international attention at Jiangsu Yancheng coastal wetland on the west coast of the Pacific Ocean in recent decades. Tidal creek is an important channel for material exchange between sea and land and plays an important role in the connectivity of water in coastal wetlands. The tidal flats from Sheyang Port to Liangduo Estuary in Jiangsu Province were selected and divided into five sub-study areas using each port as a split point.

The immunolocalization of cluster of differentiation 31, phalloidin and alpha smooth muscle actin on vascular network of normal and ischemic rat brain.

Cluster of differentiation 31 (CD31), phalloidin and alpha smooth muscle actin (α-SMA) have been widely applied to label the cerebral blood vessels in the past years. Although CD31 is mainly used as endothelial marker in determining the cerebral capillaries, it seems likely that its labeling efficiency is closely correlated with the antibodies from the polyclonal or monoclonal one, as well as the conditions of blood vessels. In order to test this phenomenon, we compared the labeling characteristics of goat polyclonal anti-CD31 (gP-CD31) and mouse monoclonal anti-CD31 (mM-CD31) with those of phalloidin and α-SMA on the rat brain in health and ischemia/reperfusion (I/R) with the middle cerebral artery occlusion.

Consumption-driven freight turnover of interprovincial trade and related air pollution emissions in China from 2007 to 2012.

Freight transport has become increasingly important regarding CO and air pollutant emissions in China but has rarely been assessed using consumption-based methods. Based on the multi-regional input-output tables of China, in this work, we use structural path analysis (SPA) to link interprovincial trade-related freight turnover to responsible sectors of final consumption. We find that from 2007 to 2012, the interprovincial trade turnover in China increased by 39% and reached 3.

Assessment of Fish Diversity in the Ma'an Archipelago Special Protected Area Using Environmental DNA.

This study aimed to investigate the practical validity of the environmental DNA (eDNA) method for evaluating fish composition and diversity in different habitats. We evaluated the fish composition and diversity characteristics of seven different habitats in the Ma'an Archipelago Special Protected Area in April 2020. The results showed that a total of twenty-seven species of fishes belonging to six orders, eighteen families, and twenty-three genera of the Actinopterygii were detected in the marine waters of the Ma'an Archipelago Special Protected Area.

The CARDS toxin of induces a positive feedback loop of type 1 immune response.

Background: Within the past 3-5 years, has become a major pathogen of community-acquired pneumonia in children. The pathogenic mechanisms involved in infection have not been fully elucidated.

Methods: Previous protein microarray studies have shown a differential expression of CXCL9 after infection.

A bio-orthogonally functionalized chitosan scaffold with esterase-activatable release for nerve regeneration.

Developing nerve conduits with biological cues is a promising approach for repairing peripheral nerve injuries. Although most biological cues incorporated into conduits generally exert their biological functions at the surface, they could not be released into the on-demand regeneration sites under physiological conditions. Herein, we firstly report a bio-orthogonally functionalized chitosan scaffold with esterase-activatable release for peripheral nerve regeneration.

Evolving landscape of PD-L2: bring new light to checkpoint immunotherapy.

Immune checkpoint blockade therapy targeting programmed cell death protein 1 (PD-1) has revolutionized the landscape of multiple human cancer types, including head and neck squamous carcinoma (HNSCC). Programmed death ligand-2 (PD-L2), a PD-1 ligand, mediates cancer cell immune escape (or tolerance independent of PD-L1) and predicts poor prognosis of patients with HNSCC. Therefore, an in-depth understanding of the regulatory process of PD-L2 expression may stratify patients with HNSCC to benefit from anti-PD-1 immunotherapy.