Publications by authors named "YuQi Sun"

In cold environments, such as polar regions and high latitudes, the freezing of aqueous solutions plays a crucial role in releasing and transforming nutrients, organic compounds, and trace gases. Freezing processes typically affect biogeochemical cycles and environmental processes by reducing the rate of chemical reactions. However, substantial studies have found that some chemical reactions may accelerate unexpectedly under freezing conditions.

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Background: Laparoscopic gastrectomy lacks hand-direct tactile sense and has a limited surgical field compared to laparotomy. Apart from textbook classification, there are anatomical variations in the gastric arteries. Laparoscopic gastrectomy presents technical difficulties and necessitates a more comprehensive comprehension of regional anatomy than open surgical procedures.

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Background: Population ageing and cancer burden are important global public health problems that pose unprecedented threats to health systems worldwide. Frailty is a common health problem among elderly patients with cancer. In recent years, the use of prehabilitation to improve frailty has received widespread attention.

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In this study, a novel polyacrylate-co-vinyl imidazole hydrogel-supported palladium (Pd) catalyst (P(AA-co-VI)@Pd) was prepared through heat-initiated polymerization, starting with the formation of a complex between vinyl imidazole and palladium chloride, followed by the addition of 75% neutralized acrylic acid (AA), crosslinking agent, and initiator. The structure and morphology of the catalyst were characterized using ICP-OES, SEM, EDX, Mapping, FT-IR, TGA, XRD, XPS and TEM techniques. It was confirmed that the catalyst exhibited excellent compatibility with water solvent and uniform distribution of Pd.

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Article Synopsis
  • The regulation of the bone microenvironment, including pH levels and metal ions, is crucial for the functions of osteoblasts and osteoclasts, which play a key role in bone regeneration.
  • A newly designed resorbable bone regeneration membrane (PCL/DEX@Ca-Zol) combines a drug-loaded metal-organic framework to address challenges in enhancing osteogenesis effectively.
  • The membrane releases calcium ions, zoledronic acid, and dexamethasone in response to acidic conditions at bone defects, helping to normalize pH, promote bone cell differentiation, and inhibit bone resorption, leading to improved bone regeneration with fewer side effects.
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  • - The study aimed to evaluate the effectiveness and safety of ivarmacitinib, a JAK 1 inhibitor, in patients with moderate-to-severe rheumatoid arthritis (RA) who did not respond adequately to standard treatments.
  • - Participants were divided into three groups to receive either placebo, ivarmacitinib 4 mg, or 8 mg once daily, with primary outcomes measured after 24 weeks based on 20% improvement in RA symptoms (ACR20).
  • - Results showed significantly higher improvement rates in those taking ivarmacitinib compared to placebo, with manageable safety concerns, indicating it could be a promising option for this patient population.
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  • The article by Koizumi examines therapeutic targets for fibrosis in alcohol-related liver disease (ALD) and highlights elafibranor (EFN) as a dual agonist for PPARα and PPARδ.
  • EFN, currently in phase III trials for other liver diseases, shows promise in reducing hepatic steatosis and fibrosis in ALD by activating PPARα and promoting fat metabolism.
  • Additionally, EFN improves the gut-liver axis and intestinal barrier function, alleviating inflammation and contributing to overall liver health.
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Introduction: Gastric cancer patients receiving neoadjuvant chemotherapy (NACT) are more vulnerable to perioperative stress. Enhanced recovery after surgery (ERAS) is widely used in surgical patients aiming at reducing stress responses. However, whether this approach is safe and feasible for gastric cancer patients received minimally invasive radical gastrectomy after NACT remained determined.

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Aberration-corrected gratings are widely applied in spectral analysis owing to their dispersion and convergence properties. However, the phase distribution error of the exposure interference field reduces the accuracy of the groove density distribution, making it difficult to satisfy the needs of high-precision spectral instruments. Therefore, this paper establishes an error model for the phase distribution of the spherical wave exposure interference field, describing the relationship between the phase distribution error and the recording parameter error.

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  • PRDX1 is an antioxidant protein with chaperone activity, found to promote colorectal cancer (CRC) progression by inhibiting the degradation of NRF2, which is crucial for cellular defense.
  • When PRDX1 is knocked out, there’s a significant reduction in CRC development, indicating its role in cancer promotion through the regulation of NRF2 and GPX4.
  • The study suggests that targeting PRDX1, especially its Cys83 residue, could provide a new therapeutic strategy for CRC by enhancing NRF2 activity and preventing cell death pathways associated with cancer.
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Cesium-formamidinium lead triiodide perovskite quantum dot (CsFAPbI PQD) is very promising for photovoltaic applications due to its good phase stability and outstanding optoelectronic properties. However, achieving the CsFAPbI PQDs with tunable compositions and robust surface matrix remains a challenge. Here, the surface matrix-mediated cation exchange of PQDs is proposed, in which a bi-functional molecule, tetrafluoroborate methylammonium (FABF), is applied for the cation exchange and stabilizing surface matrix of PQDs.

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The treatment of elderly patients diagnosed with acute myeloid leukemia (AML) poses significant challenges. Currently, one promising strategy in therapeutic interventions for geriatric individuals revolves around the utilization of small molecule targeted drugs either independently or in conjunction with demethylating agents. In this report, we present the successful attainment of complete remission in an elderly female patient with relapsed AML, the patient underwent treatment with a combination of Selinexor, decitabine, and a half-dose CAG regimen for two cycles.

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Discharge of improperly treated sulfamethoxazole (SMX) wastewater seriously threats environmental security and public health. Anaerobic dynamic membrane bioreactors (AnDMBRs) technology would be cost-effective for SMX wastewater treatment, considering its low cost and satisfactory treatment efficiency. The performance of AnDMBR, though demonstrated to be excellent in treating many types of wastewaters, was for the first time investigated for treating SMX wastewater.

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Gametogenesis, the intricate developmental process responsible for the generation of germ cells (gametes), serves as a fundamental prerequisite for the perpetuation of the reproductive cycle across diverse organisms. The enzyme is a putative ubiquitin E3 ligase implicated in the intricate regulatory mechanisms underlying cellular proliferation and division processes. The present study delves into the function of G2/M phase-specific E3 ubiquitin protein ligase () in gametogenesis in Chinese Tongue Sole ().

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Background: Obesity, characterized by excessive adiposity, is associated with brain structural abnormalities. Nevertheless, the relationships between altered structural nodes of default mode network (DMN), body mass index (BMI), general cognitive ability remained unclear in young adults.

Methods: In this study, we divided a large sample of young adults into three BMI-based groups.

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The controlled regulation of A-site in rare earth manganate perovskites can orderly arrange the electronic states, leading to the emergence of unique transport properties. However, it is challenging to balance crystal structure stability and property variations during the multi-ion doping. In this study, a series of multivalent manganate perovskites are synthesized by hydrothermal method through the A-site multielement doping, which enables the manganese atoms with varying valence states to orderly arrange at the B site.

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Objective: Post-stroke dysphagia (PSD) is a common complication of stroke. Acupuncture as one of the traditional therapies in traditional Chinese medicine (TCM), can change the excitability of cerebral cortical nerve cells, and promote the recovery of neurological and swallowing functions. Several clinical primary studies (including RCTs, cohort studies, etc.

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Exploring new high-performance anode materials is of great significance for next generation renewable energy technologies. Two-dimensional (2D) transition metal borides, named as MBenes, are receiving increasing attention in energy storage fields due to their structure-and-composition diversities and high electrical conductivities. Expanding the family of hexagonal MBenes to non-transition metal borides, we report two hexagonal IIA metal MB-typed MBenes and demonstrate the feasibility of exfoliation and application as anode materials for Li-ion batteries (LIBs) and Na-ion batteries (SIBs) using calculations.

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Next-generation light-emitting applications such as displays and optical communications require judicious control over emitted light, including intensity and angular dispersion. To date, this remains a challenge as conventional methods require cumbersome optics. Here, we report highly directional and enhanced electroluminescence from a solution-processed quasi-2-dimensional halide perovskite light-emitting diode by building a device architecture to exploit hybrid plasmonic-photonic Tamm plasmon modes.

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Light-emitting diodes (LEDs) based on metal halide perovskites (PeLEDs) with high colour quality and facile solution processing are promising candidates for full-colour and high-definition displays. Despite the great success achieved in green PeLEDs with lead bromide perovskites, it is still challenging to realize pure-red (620-650 nm) LEDs using iodine-based counterparts, as they are constrained by the low intrinsic bandgap. Here we report efficient and colour-stable PeLEDs across the entire pure-red region, with a peak external quantum efficiency reaching 28.

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We propose a spatial heterodyne Raman spectrometer (SHRS) based on a field-widened grating-echelle (FWGE). A normal grating is combined with an echelle grating in a conventional spatial heterodyne spectrometer to eliminate ghost images without using masks, and prevents interference among the spatial frequencies of different diffraction orders. Mathematical expressions and derivation processes are given for the spectral parameters in the FWGE-SHRS and a verification breadboard system is fabricated.

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We propose a high-resolution, broad-spectral-range spatial heterodyne Raman spectrometer (SHRS) having separate filters and multi-gratings (SFMG). A prototype of the SFMG-SHRS is built using multi-gratings with four sub-gratings having groove densities of 320, 298, 276, and 254 gr/mm and separate filters with filter bands corresponding to the sub-gratings. We use the SFMG-SHRS to measure the Raman spectra of inorganic and organic compounds with various integration times, laser power, and transparent containers, compare measurements of microplastics with and without the separate filters, and measure mixtures of inorganic powders and organic solutions.

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Article Synopsis
  • The study focuses on the role of Hmga2, a transcriptional activator, in hematopoietic stem cells (HSCs) under stress conditions, such as chemotherapy and inflammation.
  • Overexpressing Hmga2 helps HSCs expand during stress, while knocking it out leads to a decrease in HSC and megakaryocyte progenitor cell numbers.
  • The research identifies a mechanism involving CK2-induced phosphorylation of Hmga2 that enhances its binding to chromatin and activates anti-inflammatory genes, revealing a key regulatory axis that may also be relevant in human myelodysplastic syndrome.
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