Publications by authors named "YuLu Bao"

Article Synopsis
  • Stem cell therapies show great potential for treating chronic wounds, but issues like limited lifespan and poor delivery systems complicate their use in clinical settings.
  • This study introduces a new delivery system using a photo-crosslinking collagen hydrogel to effectively transport human adipose-derived stem cells (hADSCs) to wound sites, enhancing diabetic wound healing.
  • The hADSCs encapsulated in the hydrogel maintain their viability and function for up to three weeks, leading to improved healing outcomes in diabetic mouse models by promoting new blood vessel formation and tissue repair.
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With the development of national economy, the output of waste is also increasing. People's living standards are constantly improving, and the problem of garbage pollution is increasingly serious, which has a great impact on the environment. Garbage classification and processing has become the focus of today.

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Gastric cancer is a common malignant tumor of the digestive system. Its occurrence and development are the result of a combination of genetic, environmental, and microbial factors. infection is a chronic infection that is closely related to the occurrence of gastric tumorigenesis.

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Similar to DNA epigenetic modifications, multiple reversible chemical modifications on RNAs have been uncovered in a new layer of epigenetic modification. N6-methyladenosine (mA), a modification that occurs in ~30% transcripts, is dynamically regulated by writer complex (methylase) and eraser (RNA demethylase) proteins, and is recognized by reader (mA-binding) proteins. The effects of mA modification are reflected in the functional modulation of mRNA splicing, export, localization, translation, and stability by regulating RNA structure and interactions between RNA and RNA-binding proteins.

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The human genome contains thousands of noncoding RNAs (ncRNAs), which are thought to lack open reading frames (ORFs) and cannot be translated. Some ncRNAs reportedly have important functions, including epigenetic regulation, chromatin remolding, protein modification, and RNA degradation, but the functions of most ncRNAs remain elusive. Through the application and development of ribosome profiling and sequencing technologies, an increasing number of studies have discovered the translation of ncRNAs.

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