With the development of national economy, the output of waste is also increasing. People's living standards are constantly improving, and the problem of garbage pollution is increasingly serious, which has a great impact on the environment. Garbage classification and processing has become the focus of today.
View Article and Find Full Text PDFGastric cancer is a common malignant tumor of the digestive system. Its occurrence and development are the result of a combination of genetic, environmental, and microbial factors. infection is a chronic infection that is closely related to the occurrence of gastric tumorigenesis.
View Article and Find Full Text PDFSimilar to DNA epigenetic modifications, multiple reversible chemical modifications on RNAs have been uncovered in a new layer of epigenetic modification. N6-methyladenosine (mA), a modification that occurs in ~30% transcripts, is dynamically regulated by writer complex (methylase) and eraser (RNA demethylase) proteins, and is recognized by reader (mA-binding) proteins. The effects of mA modification are reflected in the functional modulation of mRNA splicing, export, localization, translation, and stability by regulating RNA structure and interactions between RNA and RNA-binding proteins.
View Article and Find Full Text PDFThe human genome contains thousands of noncoding RNAs (ncRNAs), which are thought to lack open reading frames (ORFs) and cannot be translated. Some ncRNAs reportedly have important functions, including epigenetic regulation, chromatin remolding, protein modification, and RNA degradation, but the functions of most ncRNAs remain elusive. Through the application and development of ribosome profiling and sequencing technologies, an increasing number of studies have discovered the translation of ncRNAs.
View Article and Find Full Text PDF