Bacterial outer membrane vesicles-cloaked modified zein nanoparticles for oral delivery of paclitaxel.

To improve the aqueous solubility and oral bioavailability of paclitaxel (PTX), a biomimetic system for oral administration of PTX was efficiently developed as an outer membrane vesicle (OMVs) of sodium caseinate (CAS) modified zein nanoparticles (OMVs-Zein-CAS-PTX-NPs) by . To verify their structure and properties, the designed nanostructures were thoroughly characterized using various characterization techniques. The results indicated that hydrogen bonds and van der Waals forces mainly drove the interaction between PTX and Zein, but the complex is unstable.

Chemical Composition of Essential Oils from Three Rhododendron Species and Their Repellent, Insecticidal and Fumigant Activities.

In order to assess the repellent, contact, and fumigant properties of three essential oils (EOs) from Rhododendron species in China against adults of Tribolium castaneum, Lasioderma serricorne, Sitophilus oryzae, this study analyzed their chemical components. The three EOs were extracted by hydrodistillation from leaves of Rhododendron species, including R. davidsonianum, R.

Membrane-cloaked polydopamine modified mesoporous silica nanoparticles for cancer therapy.

To improve the shortcomings of narrow therapeutic range and low bioavailability of traditional preparations, a composite drug carrier that combines the advantages of biological carriers and synthetic carriers was prepared in this project. The biomimetic nano-delivery system outer membrane vesicles-polydopamine-mesoporous silica nanoparticle (OMVs-PDA-MSN-DOX) for oral administration is composed of OMVs ofas shell and doxorubicin-loaded MSN modified by PDA as core. Several characterization techniques thoroughly examined the nano-drug delivery system to confirm its surface morphology and chemical property.

Study on Gas Chromatographic Fingerprint of Essential Oil from Flowers and Its Repellent Activities against Three Stored Product Insects.

The objective of this study was to establish the chromatographic fingerprints of the essential oil (EO) from flowers collected from various natural sites by gas chromatography (GC) combined with chemometric methods. The EO was obtained by hydrodistillation, and its chemical composition was analyzed by gas chromatography-mass spectrometry (GC-MS). Most components were identified as ketones and the relatively high-content components were fitone (38.

Contact toxicity and repellence of essential oil from and its major components against three stored product insects.

The objective of this work was to investigate the chemical compositions of the essential oil (EO) extracted from by hydrodistillation and their insecticidal activities against , and . The chemical profile of the EO were analyzed by gas chromatography-mass spectrometry (GC-MS), and 20 compounds were identified which accounted for 88.03% of the total EO.

Chemical composition of essential oils from four Rhododendron species and their repellent activity against three stored-product insects.

The objective of this work was to analyze four essential oils (EOs) from Rhododendron species in China and evaluate their repellent activity against Tribolium castaneum, Lasioderma serricorne, and Liposcelis bostrychophila adults. These four EOs from Rhododendron species, including R. capitatum, R.

Toxic and Repellent Effects of Volatile Phenylpropenes from on and .

Toxic and repellent effects of the essential oil from Fr. Schmidt var. mandshuricum (Maxim.

Supercritical carbon dioxide extract of Cinnamomum cassia bark: toxicity and repellency against two stored-product beetle species.

The extract from Cinnamomum cassia Presl bark was obtained with supercritical CO fluid extraction (SFE). Chemical components of the SFE extract were characterized by GC-MS spectrometry. The repellency and contact toxicity of the SFE extract were evaluated against the adults of Tribolium castaneum and Lasioderma serricorne along with those of its two main compounds.

3-(2,4-Dichloro-phen-yl)-5-(4-fluoro-phen-yl)-2-phenyl-7-(trifluoro-meth-yl)pyrazolo-[1,5-a]pyrimidine.

In the title compound, C(25)H(13)Cl(2)F(4)N(3), there are four planar systems, viz. three benzene rings and a pyrazolo-[1,5-a]pyrim-idine system [r.m.

[Constituents and bioactivities of Lamiophlomis rotata].

Objective: To investigate the chemical constituents from Lamiophlomis rotata and the bioactivities of 8-epideoxyloganic acid.

Method: The constituents were isolated by using a combination of various chromatographic techniques including column chromatography over ployamide, silica gel and Sephadex LH-20. Structures of the isolates were identified by spectroscopic data analysis.