The effect of dexmedetomidine on acute kidney injury after elective major abdominal surgery : a retrospective single-center propensity score matched study.

Background: Major abdominal surgery is a kind of high-risk surgery type for postoperative acute kidney injury (AKI) among non-cardiac surgeries. Despite dexmedetomidine exerts significant renal protective effects in cardiac surgeries and animal studies, whether it is associated with a lower incidence of AKI in major abdominal surgeries remains unclear.

Methods: From January 2019 to July 2021, patients undergoing elective major abdominal surgery in West China Hospital were enrolled.

Modified Method of Scalp Fixation Promotes Survival of Complete Scalp Avulsion Replantation.

A complete scalp avulsion injury is rare but extremely challenging to treat. Because of the dense blood vessel bundles in the scalp, replantation failure may occur if there is a subcutaneous hematoma. The method of scalp fixation is crucial for replantation to be successful.

[Unilateral biportal endoscopic posterior cervical foraminotomy for cervical radiculopathy].

Objective: To investigate the clinical efficacy of posterior unilateral biportal endoscopic(UBE) cervical discectomy for cervical radiculopathy under general anesthesia.

Methods: A retrospective analysis of 35 patients with cervical disc herniation uderwent posterior UBE cervical discectomy under general anesthesia from March 2021 to March 2023 was performed, including 17 males and 18 females, with an average age of (56.00±7.

Mapping Biodiversity Conservation Priorities for Protected Areas for Spatial Optimization: A Case Study in the Songnen Plain, China.

The decline in biodiversity poses a serious threat to natural ecosystems and has become one of the most pressing global environmental issues. Establishing conservation priorities for protected areas (PAs) is one of the most direct and effective biodiversity conservation measures. However, conservation gaps arise as a result of existing problems in spatial layout of PAs, including overlapping protection scopes, artificial fragmentation of natural ecological regions, as well as "over-protection" and "over-exploitation.

Insight into the Antibacterial Activities of Pyridinium-Based Cationic Pillar[5]arene with Controllable Hydrophobic Chain Lengths against .

The increasing number of infections caused by pathogenic bacteria has severely affected human society. More and more deaths were originated from Gram-positive methicillin-resistant (MRSA) infection each year. The potential and excellent bacteriostatic activity and resistance to biofilm formation of pillar[5]arene with different functional groups attract important attention to further study the relationship between antimicrobial activity and cytotoxicity by varying the length of the hydrophobic chain, the number of positive charges, and the hydrophobic/hydrophilic balance of the molecule.

Digital light printing of zirconia/resin composite material with biomimetic graded design for dental application.

Objective: Stress concentration and excessive wear on the opposite jaw teeth are the main problems that lead to the failure of all-ceramic crown restoration. The objectives of this study were to: (1) Synthesize the biomimetic gradient zirconia/resin composites. (2) Control the porosity and structure so that the mechanical properties of the biomimetic gradient zirconia/resin composites are close to enamel and dentin.

Flexomagnetoelectric Effect in Sr_{2}IrO_{4} Thin Films.

Symmetry engineering is explicitly effective to manipulate and even create phases and orderings in strongly correlated materials. Flexural stress is universally practical to break the space-inversion or time-reversal symmetry. Here, by introducing strain gradient in a centrosymmetric antiferromagnet Sr_{2}IrO_{4}, the space-inversion symmetry is broken accompanying a nonequivalent O p-Ir d orbital hybridization along the z axis.

Detection of biological loads in sewage using the automated robot-driven photoelectrochemical biosensing platform.

Real-time polymerase chain reaction (RT-PCR) remains the most prevalent molecular detection technology for sewage analysis but is plagued with numerous disadvantages, such as time consumption, high manpower requirements, and susceptibility to false negatives. In this study, an automated robot-driven photoelectrochemical (PEC) biosensing platform is constructed, that utilizes the CRISPR/Cas12a system to achieve fast, ultrasensitive, high specificity detection of biological loads in sewage. The Shennong-1 robot integrates several functional modules, involving sewage sampling and pretreatment to streamline the sewage monitoring.

The evolutionary advantage of artemisinin production by Artemisia annua.

Artemisinin, a potent antimalarial compound, is predominantly derived from Artemisia annua. The uniqueness of artemisinin production in A. annua lies in its complex biochemical pathways and genetic composition, distinguishing it from other plant species, even within the Asteraceae family.

Integrated ubiquitomics characterization of hepatocellular carcinomas.

Background And Aims: Patients with aggressive HCC have limited therapeutic options. Therefore, a better understanding of HCC pathogenesis is needed to improve treatment. Genomic studies of HCC have improved our understanding of cancer biology.

Alcohol drinking triggered decrease of oxidative balance score is associated with high all-cause and cardiovascular mortality in hypertensive individuals: findings from NHANES 1999-2014.

Background: Oxidative stress is closely associated with hypertensive outcomes. The oxidative balance score (OBS) measures oxidative stress exposure from dietary and lifestyle elements. The objective of this study was to investigate the association between OBS and mortality in hypertensive patients.

New Family of Benzimidazole-Based Chitosan Derivatives against .

is the major fungus that causes blue mold and produces patulin, threatening human health. Due to health and environmental pollution concerns, chitosan (CS) has attracted more and more attention as a safer alternative to synthetic fungicides for the control of blue mold. In the present study, four different benzimidazole groups were introduced onto CS by the acylation reaction to obtain benzimidazole-based chitosan derivatives (R1b-R4b).

Type 2 diabetes mellitus modifies and mediates the association between the visceral adiposity index and depression: A cross-sectional study using NHANES 2005-2018 data.

Background: The objective of this investigation was to explore the correlation between the visceral adiposity index (VAI) and depression, and to analyze how type 2 diabetes mellitus (T2DM) may influence this relationship.

Methods: This study included data of 12,378 participants sourced from the National Health and Nutrition Examination Survey (NHANES) 2005-2018. Utilizing multivariate logistic regression and restricted cubic spline (RCS) regression, we examined the correlation between VAI and depression.

Carrier-phonon decoupling in perovskite thermoelectrics via entropy engineering.

Thermoelectrics converting heat and electricity directly attract broad attentions. To enhance the thermoelectric figure of merit, zT, one of the key points is to decouple the carrier-phonon transport. Here, we propose an entropy engineering strategy to realize the carrier-phonon decoupling in the typical SrTiO-based perovskite thermoelectrics.

Solid pseudopapillary neoplasms of the pancreas (SPNs): diagnostic accuracy of CT and CT imaging features.

Purpose: To summarize the abdominal computed tomography (CT) imaging and clinicopathological data of patients with SPNs of the pancreas and analyze the accuracy of preoperative CT diagnosis and features.

Materials And Methods: Between June 2006 and June 2023, CT images of 120 histopathologically proven SPNs in the pancreas were retrospectively reviewed. Fifteen features, including age, sex, and CT-determined features, were included in a multiple stepwise regression analysis.

Non-invasive diagnosis of pulmonary nodules by circulating tumor DNA methylation: A prospective multicenter study.

Background: With the popularization of computed tomography, more and more pulmonary nodules (PNs) are being detected. Risk stratification of PNs is essential for detecting early-stage lung cancer while minimizing the overdiagnosis of benign nodules. This study aimed to develop a circulating tumor DNA (ctDNA) methylation-based, non-invasive model for the risk stratification of PNs.

Comparative Study of the Antibacterial Effects of S-Nitroso-N-acetylcysteine and Sodium Nitrite against and Their Application in Beef Sausages.

This study investigated the antibacterial effects of S-nitroso-N-acetylcysteine (SNAC) and sodium nitrite (NaNO) against and their application in beef sausages. Both SNAC and NaNO demonstrated pH-responsive antibacterial activity, with SNAC showing greater efficacy than NaNO ( < 0.05) at the same pH (3, 5, and 7).

Gui Qi Zhuang Jin Decoction ameliorates mitochondrial dysfunction in sarcopenia mice via AMPK/PGC-1α/Nrf2 axis revealed by a metabolomics approach.

Objective: Sarcopenia, as a condition of muscle mass loss and functional decline typically diagnosed in elderly individuals, severely affects human physical activity, metabolic homeostasis, and quality of life. Gui Qi Zhuang Jin Decoction (GQZJD), an approved hospital-based prescription with years of clinical application, has been demonstrated to have a notable therapeutic effect on sarcopenia. However, its potential mechanism of action in the treatment of sarcopenia remains uncertain.

Trends and Directions in Oats Research under Drought and Salt Stresses: A Bibliometric Analysis (1993-2023).

With global climate change leading to increasing intensity and frequency of droughts, as well as the growing problem of soil salinization, these factors significantly affect crop growth, yield, and resilience to adversity. Oats are a cereal widely grown in temperate regions and are rich in nutritive value; however, the scientific literature on the response of oat to drought and salt stress has not yet been analyzed in detail. This study comprehensively analyzed the response of oat to drought stress and salt stress using data from the Web of Science core database and bibliometric methods with R (version4.