Periodontitis and the Risk of Heart Failure:a Meta-analysis and Mendelian Randomisation Study.

Purpose: Periodontitis and heart failure (HF) impact millions of individuals globally with heavy social and economic burden. Prior research has indicated a connection between them. However, the conclusions have been somewhat inconsistent.

High-yield synthesis of FeNC as support of PtFe nanoparticles for the oxygen reduction reaction by a green ball milling method.

Enhancing catalytic activity, durability and reducing costs are major challenges in commercialization of proton exchange membrane fuel cells (PEMFCs). Non-precious metal catalysts face durability challenges when applied to PEMFCs, while platinum (Pt)-based catalysts are hampered by their high costs and weak interactions with carbon supports, limiting their application in PEMFCs. Combining Pt-based catalysts with iron-nitrogen-carbon (FeNC) supports can improve the oxygen reduction reaction performance.

Clinical and Prognostic Implications of an Alternative Splicing-related Risk Model Based on TP53 Status in Breast Cancer.

Background: Breast Cancer (BRCA) is one of the most common cancers worldwide. Abnormal Alternative Splicing (AS) is frequently observed in cancers. Understanding the intricate relationship between gene mutations and abnormal AS is vital for developing novel diagnostic and therapeutic strategies to effectively target cancer.

Identification of novel serum lipid metabolism potential markers and metabolic pathways for oral cancer: a population-based study.

Objective: This study aims to identify potential lipid biomarkers and metabolic pathways associated with oral cancer (OC). Then to establish and evaluate disease classification models capable of distinguishing OC patients from healthy controls.

Methods: A total of 41 OC patients and 41 controls were recruited from a hospital in Southeast China to examine the serum lipidomics by Ultra-high Performance Liquid Chromatography Q Exactive Mass Spectrometry (UHPLC-QE-MS).

Iron-Catalyzed Cross-Dehydrogenative Coupling.

This review highlights significant advances in iron-catalyzed cross-dehydrogenative coupling (CDC), a method pivotal for forming carbon-carbon (C-C) bonds directly from C-H bonds. This technique uses iron-a naturally abundant, inexpensive, and environmentally benign transition metal-as a catalyst to facilitate the coupling of two unfunctionalized C-H bonds. This method stands out for avoiding pre-functionalized substrates, reducing both waste and cost in organic synthesis.

Lycopene Alleviates Depression-Like Behavior in Chronic Social Defeat Stress-Induced Mice by Promoting Synaptic Plasticity via the BDNF-TrkB Pathway.

Lycopene is a natural plant extract widely studied for its powerful antioxidant and neuroprotective effects. Emerging evidence suggests that it also possesses potential antidepressant properties. Compared to commonly used clinical antidepressants, lycopene offers higher safety; however, its underlying mechanisms remain unclear.

L1CAM extracellular vesicles derived from the serum of adolescents with major depressive disorder induce depression-like phenotypes in adolescent mice.

Background: It has been reported that L1 cell adhesion molecule (L1CAM) antibody can capture neuron-derived extracellular vesicles (NDEVs) derived from peripheral blood. This antibody is significantly associated with occurrence of adult psychiatric disorders. However, the role and mechanism of L1CAM EVs (L1 EVs) in adolescent with major depressive disorder (AMDD) is not well understood.

Streptococcus agalactiae infection of a reconstructed human respiratory epithelium revealed infection and host response characteristics by different serotypes.

Background: Streptococcus agalactiae poses a significant threat to neonatal health, causing morbidity and mortality when transmitted from the maternal vagina to the newborn's respiratory tract. Among its various strains, serotype III is predominant in severe neonatal infections in Asia. However, the mechanisms of pathogenesis and host responses underlying serotype-specific disease outcomes remain poorly understood.

Relationship Between Fear of Childbirth and Oral Health-Related Quality of Life in Pregnant Women: The Mediating Effect of Pregnancy Anxiety.

Background: Psychosocial health affects oral health-related quality of life. Pregnancy, as a special time for women, produces significant psychological changes. However, the relationship between mental health during pregnancy and oral health-related quality of life is unclear.

Multidimensional stress and self-harm in Chinese preadolescents: A cross-sectional study.

Background: Limited research has been conducted on self-harm among preadolescents in China. This study investigated the influence of multidimensional stress on high levels of self-harm behavior in preadolescents.

Method: This large-scale cross-sectional study of 7-14-year-old primary school students in grades 3-6 was conducted in Southwest China between September and December 2020.

Multimodal Ultrasound Imaging in the Diagnosis of Primary Giant Cell Tumor of the Breast: A Case Report and Literature Review.

Giant cell tumor of soft tissue (GCT-ST) is an extremely rare phenomenon in the breast. Herein, a case involving a 75-year-old female with a painless lump and bloody discharge from the nipple of her left breast is reported. A diagnosis of malignant tumor was arrived at by observing the location of the tumor, interior echo, margins, vascular distribution, hardness, and microvascular density on preoperative multimodal ultrasonography.

JointLIME: An interpretation method for machine learning survival models with endogenous time-varying covariates in credit scoring.

In this work, we introduce JointLIME, a novel interpretation method for explaining black-box survival (BBS) models with endogenous time-varying covariates (TVCs). Existing interpretation methods, like SurvLIME, are limited to BBS models only with time-invariant covariates. To fill this gap, JointLIME leverages the Local Interpretable Model-agnostic Explanations (LIME) framework to apply the joint model to approximate the survival functions predicted by the BBS model in a local area around a new individual.

Bidirectional Association Between Parental Pressure to Eat and Children's Satiety Responsiveness: The Moderating Effect of Children's Temperament.

This study aimed to examine the directionality of the relationship between children's satiety responsiveness and parental pressure to eat and to explore how children's temperament moderates this relationship. Parents of preschoolers (n = 482, M = 3.66, SD = 0.

Parental Feeding Practices, Weight Perception, and Children's Appetitive Traits Are Associated with Weight Trajectories in Preschoolers: A Longitudinal Study in China.

Objective: This study aimed to examine the trajectories of body mass index-for-age z-score (BAZ) in preschoolers and its association with parental feeding practices, weight perception, and children's appetitive traits.

Methods: A total of 433 preschoolers and their parents from eight public kindergartens in Shanghai were assessed annually over two years. A group-based trajectory model was employed to identify distinct BAZ patterns.

Single-crystalline High-κ GdOCl dielectric for two-dimensional field-effect transistors.

Two-dimensional (2D) dielectrics, integrated with high-mobility semiconductors, show great promise to overcome the scaling limits in miniaturized integrated circuits. However, the 2D dielectrics explored to date still face the challenges of low crystallinity, diminished dielectric constant, and the lack of effective synthesis methods. Here, we report the controllable synthesis of ultra-thin gadolinium oxychloride (GdOCl) nanosheets via a chloride hydrate-assisted chemical vapor deposition (CVD) method.

Versatile Hydrogel Based on a Controlled Microphase-Separation Strategy for Both Liquid- and Solid-Phase 3D Printing.

Hydrogels are considered indispensable materials for fabricating flexible devices with their excellent flexibility and workability. To efficiently transform hydrogels into flexible devices, three-dimensional printing technology offers a powerful approach. However, hydrogels suitable for a single printing strategy have proven inadequate for fabricating flexible integrated devices.

Wrinkled Rhenium Disulfide for Anisotropic Nonvolatile Memory and Multiple Artificial Neuromorphic Synapses.

Two-dimensional materials are emerging as potential solutions for high-density nonvolatile memory and efficient neuromorphic computing. However, integrating multidimensional memory and an ideal linear weight updating synapse in a simple device configuration to achieve versatile biomimetic neuromorphic systems remains challenging. Here, we introduce a wrinkled rhenium disulfide (ReS) transistor, where the wrinkled structure facilitates the carrier trapping/detrapping at the dielectric interface, thus enabling the fusion of nonvolatile memory and both electronic and optoelectronic synaptic functionalities.

Textile Bandwidth-Enhanced Half-Mode Substrate-Integrated Cavity Antenna Based on Embroidered Shorting Vias.

A textile bandwidth-enhanced half-mode substrate-integrated cavity (HMSIC) antenna based on embroidered shorting vias is designed. Based on the simulated results of the basic HMSIC antenna, two embroidered hollow posts with square cross-sections are added as shorting vias at the intersections of the zero-E traces of the TM210HM and TM020HM modes to shift the TM010HM-mode band to merge with the bands of the higher-order modes for bandwidth enhancement. A prototype is practically fabricated based on computerized embroidery techniques.

Relationship between illness perception and self-management behaviors among women with gestational diabetes mellitus in China during the COVID-19 pandemic: A mediating role of depression.

Objective: Describe the current status of illness perception, depression, and self-management behaviors among women with gestational diabetes mellitus (GDM) during the COVID-19 pandemic, and explore the role of depression in the relationship between illness perception and self-management behaviors among women with GDM.

Methods: Pregnant women diagnosed with GDM were recruited at the obstetrics clinic of a Grade-A tertiary hospital in Wuhan, through convenience sampling. Self-reported questionnaires including basic information, illness perception, depression, and self-management behaviors were used to collect data from April 2021 to February 2022.

Investigating vertical distributions and photochemical indications of formaldehyde, glyoxal, and NO from MAX-DOAS observations in four typical cities of China.

Formaldehyde (HCHO), glyoxal (CHOCHO), and nitrogen dioxide (NO) are crucial in atmospheric photochemical processes at both surface and elevated altitudes. This study presents synchronous multi-axis differential optical absorption spectroscopy (MAX-DOAS) measurements of the vertical distributions of summertime HCHO, CHOCHO and NO in four representative megacities within the Beijing-Tianjin-Hebei (BTH), Yangtze River Delta (YRD), Sichuan Basin (SB), and Pearl River Delta (PRD) regions of China. The vertical distributions of HCHO and CHOCHO tended to occur at higher altitudes compared to NO, influenced by both primary emissions near the ground and photochemical oxidation processes at elevated altitudes.

Effects and mechanisms of Polygonati Rhizoma polysaccharide on potassium oxonate and hypoxanthine-induced hyperuricemia in mice.

Hyperuricemia, a prevalent metabolic disturbance intricately linked to gout and chronic kidney disease (CKD), may be relieved by traditional Chinese medicine Polygonati Rhizoma. It is derived from the rhizomes of Polygonatum sibiricum, Polygonatum kingianum, and Polygonatum cyrtonema, which are rich in polysaccharides and are effective hyperuricemia alleviators. This study investigated the potential of Polygonatum sibiricum polysaccharide (PSP) in managing hyperuricemia.