[Network visual data mining and analysis of literature on electroacupuncture treatment of post-stroke sequelae].

Objective: To analyze the optimum stimulating parameters and acupoint combination law of electroacupuncture (EA) treatment of post-stroke sequelae (PSS) through the network visual data mining and analysis of the literature，so as to provide reference for clinical application.

Methods: The related articles of acupuncture treatment of PSS patients published from January 1, 2005 to December 31, 2021 were collected from databases of CNKI, Wanfang, Weipu（VIP), SinoMed, CHAOXING, DUXIU, PubMed, Ovid, Embase and Cochrane Library. After the articles were screened according to our formulated inclusion and exclusion criteria, a "Clinical Literature Database of EA Treatment of PSS" was established.

[Research status and thinking of auricular acupuncture theory].

In this paper, the articles of auricular acupuncture in recent 20 years are sorted out and analyzed, and the theory and mechanism of auricular acupuncture in different schools are summarized and compared. Eight theories are included totally, i.e.

[Characteristics of clinical application of electroacupuncture therapy for peripheral neuropathy based on data mining].

Objective: To investigate the application characteristics of electroacupuncture (EA) in the treatment of peripheral neuropathy, so as to provide a basis for clinical use of EA therapy.

Methods: Keywords of "electroacupuncture""peripheral neuropathy" "facial paralysis" "trigeminal neuralgia" "sciatica" "common peroneal nerve injury" "diabetic peripheral neuropathy" "intercostal neuralgia" "gluteal epithelial neuritis" "ulnar nerve injury" "median nerve paralysis" "postherpetic neuralgia", and "great occipital neuralgia" were used to search articles in both English and Chinese published from 1999 to 2019 in databases of CNKI, Wanfang, VIP, CBM, Ovid, PubMed and Embase and related books such as electroacupuncture, and neurology, followed by establishing a database of "Electroacupuncture Treatment of Peripheral Neuropathy". Then, the collected articles were put into statistical analysis after sorting, screening, input, checking, and data extracting by using data mining technology and statistical software EpiData.

[Application characteristics of abdominal acupuncture based on data mining technique].

Objective: To investigate the disease spectrum and predominant diseases treated by abdominal acupuncture by data mining and analysis of journal articles on abdominal acupuncture, and to provide a reference for clinical diagnosis and treatment.

Methods: Based on the database of abdominal acupuncture established by the research group, the data mining technique was used for the analysis and extraction of the articles on abdominal acupuncture included in this study.

Results: A total of 788 original journal articles were included.

[Exploration of dominant diseases and clinical application characteristics of wrist-ankle acupuncture therapy based on data mining technology].

Objective: To analyze the literature regarding wrist-ankle acupuncture therapy by data mining technology, and the dominant diseases of wrist-ankle acupuncture therapy were summarized to provide reference for evaluation of specificity effect of wrist-ankle acupuncture therapy.

Methods: The journal articles regarding wrist-ankle acupuncture therapy from the CNKI, WANFANG, and VIP since January 1, 1975 to December 31, 2017, and the medical cases regarding wrist-ankle acupuncture therapy in - and were retrieved. Based on the disease types of wrist-ankle acupuncture therapy in the journal articles and medical cases, the association rules method of data mining technology was applied to calculate frequent itemsets.

[Effect of Manual Acupuncture, Electroacupuncture and Moxibustion on Intestinal Motility and Expression of Enteric Nervous Activity Related Proteins in Functional Constipation Rats].

Objective: To compare the effect of manual acupuncture (MA), electroacupuncture (EA) and moxibustion interventions on intestinal motility and expression of enteric nervous activity related proteins calcitonin gene related peptide (CGRP), transient receptor potential vanilloid 1 (TRPV 1) and proteinase activated receptor-4 (PAR-4) in colon tissue of rats with functional constipation (FC), so as to select a better intervention method for FC.

Methods: Sixty male SD rats were randomly divided into blank control (=8), model (=11), medication (=8), MA (=11), EA (=11), and moxibustion (=11) groups. The FC model was established by gavage of suspension of loperamide hydrochlorid for 6 days.

[Research of Characteristics of Stimulation Methods and Application of Acupoint in Auricular Needle Therapy Based on Data Mining].

In the present paper, using data mining technology,the authors downloaded information from databases on auricular needle therapy, and obtained data samples from journals and academic dissertations involving the application of auricular needle therapy to treat diseases, and then screened, audited, and extracted the data and performed a statistical analysis. The authors extracted data on the application of auricular needle therapy in the stimulation methods of medicine (needling instrument), selection of the side of ear to treat disease and the number of times the ear was pressed per day and the compression time. In the stimulation methods, the needling instrument varied, the seeds of cowherb were applied in 60.

[Rule of Clinical Application of Auricular Acupuncture Based on Data Mining].

Objective: To explore the rule of clinical application of auricular acupuncture therapy by data mining in order to guide clinical practice.

Methods: The data base about single auricular acupuncture therapy for different clinical diseases was established by collection, sorting, screening, recording, collation, data extraction, statistic analysis on data samples from journals, academic theses dissertations published in near 60 years. The application rules of auricular therapy including its predominant diseases, stimulus modality, therapeutic effect, and angle of needling were summarized by data mining technique.

[Effects of Different Acupuncture and Moxibustion Methods on Plasma NO, NOS and VIP Contents and the Expression of Colonic VIP Protein in Functional Constipation Rats].

Objective: To compare the effects of filiform needling, electroacupuncture, and moxibustion on functional constipation in rats, and to explore the possible mechanism of these three different methods.

Methods: Male SD rats were randomly divided into blank control group (=8), model group (=11), medication group (=8), filiform needling group (=11), electroacupuncture group (=11), and moxibustion group (=11). Functional constipation model was established by intragastric administration with the suspension of loperamide hydrochloride, daily for six days in a week.

[Basic Regularities and Characteristics of Compound Reinforcing--reducing Manipulation of Acu- puncture Revealed by Data Mining].

Objective: To explore the regularities and features of compound reinforcing-reducing manipulation of acupuncture filiform needles in the treatment of clinical conditions or diseases by using data mining technique, so as to guide clinical practice.

Methods: At first, the data base about the reinforcing-reducing manipulation (CRRM) of filiform needles for different clinical problems was established by collection, sorting, screening, recording, collation, data extraction of the related original papers published in journals and conferences and related academic dissertations from Jan. 1 of 1950 to Jan.

[Basic Characteristics of Simplex Reinforcing and Reducing Manipulations of Filiform Acupuncture Needle in Clinical Practice Based upon Data Mining].

Objective: To explore the regularities and features of clinical application of simplex reinforcing or reducing manipulation of filiform acupuncture needles by data mining in order to guide clinical decision in a better way.

Methods: A database about simplex reinforcing and reducing manipulations of filiform acupuncture needle was established first after collection, sorting, screening, type-in, and collation of the related papers, academic dissertations and theses of academic conferences published from January 1st of 1950 to January 31 of 2015 by using key word "acupuncture" "acupuncture and moxibustion" "needle manipulation" and "filiform needle" from database of China National Knowledge Infrastructure (CNKI, a full-text database of Chinese journals), followed by data extraction and statistical analysis.

Results: A total of 1 304 articles were found to meet the standards formulated in the present study.

[Analysis of Therapeutic Regularities and Characteristics of Blood-letting Therapy for Acne Patients Based on Data Mining].

Objective: To analyze the therapeutic regularities and characteristics of blood-letting therapy for acne in the past clinical practice by using data mining.

Methods: Original papers about acne treated by pricking blood therapy were searched and screened from common databases as Chinese National Knowledge Infrastructure Database (CNKI), WanFang Data, SinoMed, Ovid, ScienceDirect, Socolar, SciFinder, Foreign Medical Journal Full-Text Service (FMJS) and PubMed using keywords of acne+bleeding therapy, acne+blood-letting, acne+ pricking blood, followed by establishing a data plateform to conduct a data mining using Online Analytical Processing (OLAP).

Results: A total of 230 original journal articles about acne treated by pricking blood therapy were collected.

[A meta-analysis on pricking blood therapy for migraine].

Objective: To evaluate the therapeutic effect of pricking blood therapy for migraine.

Methods: We searched all the original papers about pricking blood therapy for migraine in common databases as the Chinese National Knowledge Infrastructure Database (CNKI), Chinese Biomedical Library (CBM), Ovid, Science Direct, Socolar, and Sci Finder (1949 -2012), Wanfang Data (1998-2012) and Foreign Medical Journal Service (FMJS, 1990-2012). The original articles were searched in accordance with a pre-defined standards (simple pricking blood treatment, or the pricking blood therapy was the principal approach), while those about other diseases (such as cerebrovascular disease, cervical spondylosis, etc.

[Research of bleeding volume and method in blood-letting acupuncture therapy based on data mining].

Through computer-based technology and data mining method, with treatment in cases of bloodletting acupuncture therapy in collected literature as sample data, the association rule in data mining was applied. According to self-built database platform, the data was input, arranged and summarized, and eventually required data was acquired to perform the data mining of bleeding volume and method in blood-letting acupuncture therapy, which summarized its application rules and clinical values to provide better guide for clinical practice. There were 9 kinds of blood-letting tools in the literature, in which the frequency of three-edge needle was the highest, accounting for 84.

[Exploration on the application characteristics of bloodletting therapy for the diseases relevant with soft tissue infection by data mining technology].

Objective: Using the data mining technology to analyze the application law of bloodletting therapy for the diseases relevant with soft tissue infection and explore the effect specificity of bloodletting therapy.

Methods: The variety of diseases treated with bloodletting therapy was taken as the sample data by collecting the reports from the periodical literatures. The network database of bloodletting literature was set up.