Publications by authors named "Yu-xia Wu"
Article Synopsis
- This study aimed to compare the effectiveness and safety of adalimumab (ADA) with a herbal remedy called Tripterygium wilfordii (TwHF) against ADA combined with methotrexate (MTX) for patients with rheumatoid arthritis (RA) who did not respond well to MTX.
- Conducted with 64 RA patients, the trial included a treatment group (ADA + TwHF) and a control group (ADA + MTX), monitoring outcomes over 24 weeks for low disease activity and remission rates.
- Results showed no significant differences in efficacy or safety between the two treatment options, indicating that TwHF could be a viable alternative for RA patients who cannot
Article Synopsis
- The study investigates the knowledge, attitude, and practices (KAP) regarding medication among residents in Haikou, aiming to identify factors that influence medication errors.
- A cross-sectional survey collected 471 valid responses, revealing that while knowledge of medication was rated "good," attitudes and practices were rated "fair."
- Findings suggest that older age and higher education correlate with better medication knowledge, indicating a need for educational interventions, especially for those with lower educational backgrounds, to promote rational drug use and reduce errors.*
Background: Hyperthyroidism in pregnancy may pose a great threat to maternal and fetal health. The risk of hyperthyroid heart disease (HHD), even heart failure, is significantly elevated in pregnant women.
Aim: To investigate the clinical characteristics, prognosis, and therapy of HHD in pregnant women.
This retrospective cohort study attempts to investigate pregnancy complications and adverse pregnancy outcomes in women of advanced maternal age (AMA). Data were extracted from electronic medical records system at West China Second University Hospital of Sichuan University from January 2013 to July 2016. The study cohort consisted 8 subgroups of women on 4 different age levels (20-29 years, 30-34 years, 35-39 years and ≥40 years) and 2 different parities (primiparity and multiparity).
View Article and Find Full Text PDFObjective And Methods: To analyze the association between global DNA methylation and single-nucleotide polymorphisms (SNPs) in methylenetetrahydrofolate reductase (MTHFR). MTHFR polymorphisms rs1801133 and rs1801131 were detected using the restriction fragment length polymorphism method, and cytokinesis-block micronucleus (MN) frequency and global DNA methylation was measured in workers from 410 shoe factories.
Results: A multilinear regression analysis demonstrated that DNA methylation of the TT variant allele of rs1801133 was lower than that of the CC wild type allele (Exp(β) [95% CI], 0.
[The effect of low-dose hydrocortisone on the expression of glucocorticoid receptor alpha of the septic kidney and its protective effect on kidney in rat].
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue
July 2011
Objective: To investigate the protective effect and mechanism of low dose glucocorticoid(GC) on sepsis induced acute kidney injury(AKI) in rat.
Methods: Eighty healthy Wistar male rats were randomly divided into sham group (n=10), AKI model group (AKI group, n=35)and hydrocortisone treatment group(HC group, n=35),according to random digital table. Septic AKI model was reproduced using cecal ligation and puncture (CLP).
[External validity and its evaluation used in clinical trials].
Zhonghua Liu Xing Bing Xue Za Zhi
May 2011
[Methodological quality assessment of systematic reviews correlated to traditional Chinese medicine published in China].
Zhongguo Zhong Xi Yi Jie He Za Zhi
March 2011
Objective: To assess the methodological quality of systematic reviews or Meta-analysis of traditional Chinese medicine published in China, and to validate the applicability of OQAQ (Overview Quality Assessment Questionnaire) and AMSTAR (a measurement tool to assess systematic reviews) in traditional Chinese medicine (Chinese Medical).
Methods: Comprehensive literature retrieve was performed in CBM, CNKI, VIP as well as hand searching in Chinese Journal of Evidence-Based Medicine. The retrieve was started from January 1, 1999 and terminated by December 2008.
[Preliminary study on polymorphism of GSTM1, CYP2E1 and NQO1 genes and risk factors of children leukemia].
Zhonghua Liu Xing Bing Xue Za Zhi
September 2004