Publications by authors named "Yu-qin Xu"

Article Synopsis
  • The study investigates the potential of gut microbiota as predictive biomarkers for patients with postpartum depressive disorder (PPD) undergoing acupuncture treatment.
  • About 79 PPD patients were analyzed, with 55 receiving acupuncture and 24 not receiving any treatment; nearly half of those treated showed a positive response.
  • Results indicated that certain gut microbiota species were more prevalent in acupuncture responders, suggesting they could help predict treatment efficacy, but further research is necessary for validation.
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Article Synopsis
  • The study investigates the connection between immune responses and the effectiveness of acupuncture in treating postpartum depression (PPD), particularly focusing on inflammatory cytokine levels.
  • Among the 121 women with PPD, significant reductions in depression scores were observed after 8 weeks of acupuncture, yet changes in cytokine levels did not significantly differ between those who responded well to treatment and those who did not.
  • Results indicate that responders showed lower levels of certain inflammatory cytokines like IL-6 and IL-10, while non-responders had higher levels of pro-inflammatory cytokines, suggesting acupuncture may help alleviate PPD by modulating the body's inflammatory response.
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Objective: To assess the methodological quality, report quality and evidence quality of the Meta-analysis and systematic reviews of acupuncture and moxibustion for children with cerebral palsy, aiming to provide decision-making basis for clinical treatment.

Methods: The systematic reviews and Meta-analysis of acupuncture and moxibustion for children with cerebral palsy were searched in CNKI, Wanfang, VIP, SinoMed, Cochrane Library, PubMed and EMbase. The retrieval time was from the database establishment to June 30th, 2022.

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Background: Acupuncture may become a treatment for postpartum depression (PPD). Currently, little is known about the use of acupuncture in the treatment of PPD from the point of view of practitioners. The aim of this study was to explore practitioners' perspectives on the treatment of PPD with acupuncture and provide suggestions for future improvement.

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miR-30b, which is encoded by the gene located on chromosome 8q24.22, plays an important role in a variety of diseases. In most types of tumors, miR-30b significantly inhibits the proliferation, migration, and invasion of cancer cells through the regulation of target genes.

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Background: Hypopharyngeal cancer (HPC) is associated with a poor prognosis and a high recurrence rate. Immune escape is one of the reasons for the poor prognosis of malignant tumors. Programmed cell death ligand 1 (PD-L1) and programmed cell death-1 (PD-1) have been shown to play important roles in immune escape.

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Results: Results showed the overall structure of gut microbiome has no significant difference between experimental and control groups. In the genus level, the abundance of and is higher in the experiment group than in the control, whereas that of is less. The 16S KEGG function prediction suggested that Parkinson disease, retinol metabolism, and arachidonic acid metabolism could explain the biological function of different gut microbiome.

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In order to guarantee and improve the quality of acupuncture service, the developments of the control of acupuncture service quality in the World Health Organization (WHO) and various countries were summarized. A number of normative documents that could improve acupuncture service security and effectiveness have been developed in WHO and many countries, in which, acupuncture training, safety manipulation and the guidelines for clinical practice of disease have been included. There are great differences in the qualification authentication and management of acupuncture practitioners among different countries.

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Objective: To study the alkaloids from the fruit of Macleaya cordata.

Methods: The alkaloids were isolated and purified by silica gel column chromatography and preparative high performance liquid chromatography,and the structures were elucidated based on the spectral data.

Results: Eight alkaloids were obtained from the fraction of ethanol extract and identified as 6-cyanodihydrosanguinarine( 1),6-acetonyldihydrosanguinarine( 2),6-acetonyldihydrochelerythrine( 3),chelerythrine( 4),dihydrochelerythrine( 5),13,14-dehydrogen-N-methyl-coptisine( 6),N-methyl-canadine( 7) and berberine( 8).

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Two new alkaloids, named 2,3-methylenedioxy-7,10-dimethyl-7,8,9,10-tetrahydro-benzoquinoline (1) and 2,3-methylenedioxy-7,10-dimethyl-8-carboxyl-benzoquinoline (2), were detected primarily from the fruits of Macleaya cordata by their different fragmentation pathways. And then isolation of the two compounds was performed by column chromatography and preparative HPLC under the guiding of mass spectrometry. Finally, their structures were determined by spectroscopic analysis.

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