MiR-217 is involved in the carcinogenesis of gastric cancer by down-regulating CDH1 expression.

GC is one of the most leading malignancies all over the world, and is also the leading cause of cancer-related mortalities. At present, GC remains difficult to diagnose at an early stage. In this study, we first detected the expression of 9 selected miRNAs in the exosomes from 67 GC patients' circular exosomes and found 4 miRNAs level was significantly altered.

Crohn Disease of the Vulva without Gastrointestinal Manifestations in a 16-Year-Old Girl.

Background: Crohn disease of the vulva is a rare disease that is difficult to diagnose. There are limited reports describing treatment of this condition.

Objective: To describe the diagnosis and treatment of a 16-year-old girl with Crohn disease of the vulva, without onset of intestinal symptoms.

Endoscopic stenting and concurrent chemoradiotherapy for advanced esophageal cancer: a case-control study.

Aim: To evaluate the role of endoscopic stenting with or without concurrent 3-dimensional conformal chemoradiotherapy (3D-CRT) in patients with inoperable esophageal cancer.

Methods: Advanced esophageal cancer patients indicated for esophagectomy received esophageal stents. A part of patients completed 3D-CRT after stenting.