Modulation of methamphetamine memory reconsolidation by neural projection from basolateral amygdala to nucleus accumbens.

Drug-associated conditioned cues promote subjects to recall drug reward memory, resulting in drug-seeking and reinstatement. A consolidated memory becomes unstable after recall, such that the amnestic agent can disrupt the memory during the reconsolidation stage, which implicates a potential therapeutic strategy for weakening maladaptive memories. The basolateral amygdala (BLA) involves the association of conditioned cues with reward and aversive valences and projects the information to the nucleus accumbens (NAc) that mediates reward-seeking.

[Studies on sodium dodecyl sulphate-polyacrylamide gel electrophoresis atlas of protein in precious animal TCM].

Objective: To offer scientific basis of distinguish p recious animal TCM.

Method: Molecular weights of the proteins were measured by modified sodium dodecyl sulphate-polyaerylamide gel eleetrophoresis (SDS-PAGE).

Results: The bands were always quite distinct.